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Oligodendrocyte transcription factor

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Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).

Below are the list of possible Oligodendrocyte transcription factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Oligodendrocyte transcription factor 1

 Oligodendrocyte transcription factor 1 ELISA Kit
 Oligodendrocyte transcription factor 1 Recombinant
 Oligodendrocyte transcription factor 1 Antibody
Also known as Oligodendrocyte transcription factor 1 (Oligo1) (Class B basic helix-loop-helix protein 6) (bHLHb6) (Class E basic helix-loop-helix protein 21) (bHLHe21).
OLIG1: Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube.

Protein type: Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 21q22.11

Molecular Function: protein binding
 OLIG1 ELISA Kit
 OLIG1 Recombinant
 OLIG1 Antibody
 BHLHB6 ELISA Kit
 BHLHB6 Recombinant
 BHLHB6 Antibody
 BHLHE21 ELISA Kit
 BHLHE21 Recombinant
 BHLHE21 Antibody
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Oligodendrocyte transcription factor 2

 Oligodendrocyte transcription factor 2 ELISA Kit
 Oligodendrocyte transcription factor 2 Recombinant
 Oligodendrocyte transcription factor 2 Antibody
Also known as Oligodendrocyte transcription factor 2 (Oligo2).
OLIG2: Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development. A chromosomal
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aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA.

Protein type: Oncoprotein; Transcription factor

Cellular Component: cytoplasm; nucleus; transcription factor complex

Molecular Function: protein binding; protein homodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; transcription factor activity

Biological Process: myelination; negative regulation of neuron differentiation; negative regulation of transcription from RNA polymerase II promoter; nervous system development; neuron fate commitment; oligodendrocyte differentiation; positive regulation of oligodendrocyte differentiation; regulation of transcription, DNA-dependent; spinal cord motor neuron differentiation; spinal cord oligodendrocyte cell differentiation; spinal cord oligodendrocyte cell fate specification; thalamus development
 Olig2 ELISA Kit
 Olig2 Recombinant
 Olig2 Antibody
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Oligodendrocyte transcription factor 3

 Oligodendrocyte transcription factor 3 ELISA Kit
 Oligodendrocyte transcription factor 3 Recombinant
 Oligodendrocyte transcription factor 3 Antibody
Also known as Oligodendrocyte transcription factor 3 (Oligo3) (Class B basic helix-loop-helix protein 7) (bHLHb7) (Class E basic helix-loop-helix protein 20) (bHLHe20).
OLIG3: May determine the distinct specification program of class A neurons in the dorsal part of the spinal cord and suppress specification of class B neurons.

Chromosomal Location of Human Ortholog: 6q23.3

Molecular Function: protein binding
 OLIG3 ELISA Kit
 OLIG3 Recombinant
 OLIG3 Antibody
 BHLHB7 ELISA Kit
 BHLHB7 Recombinant
 BHLHB7 Antibody
 BHLHE20 ELISA Kit
 BHLHE20 Recombinant
 BHLHE20 Antibody
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