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Opiorphin prepropeptide

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Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala-pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection.

Below are the list of possible Opiorphin prepropeptide products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Opiorphin prepropeptide

 Opiorphin prepropeptide ELISA Kit
 Opiorphin prepropeptide Recombinant
 Opiorphin prepropeptide Antibody
Also known as Opiorphin prepropeptide (Basic proline-rich lacrimal protein) (Proline-rich protein 1) (PRL1).
PROL1: Opiorphin is an endogenous inhibitor of neprilysin and aminopeptidase N. Inhibits the breakdown of substance P, Mca-BK2 and Met-enkephalin by neprilysin in vitro with IC(50) values of 29 uM, 33 uM and 33 uM respectively. Inhibits the breakdown of Ala- pNA by aminopeptidase N in vitro with an IC(50) of 65 uM. Has a potent analgesic effect when administered to rats by intravenous injection. Belongs to the PROL1/PROL3 family.

Protein type: Secreted; Secreted, signal peptid
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Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular region; extracellular space

Molecular Function: endopeptidase inhibitor activity; protease inhibitor activity

Biological Process: regulation of sensory perception of pain; retinal homeostasis
 OPRPN ELISA Kit
 OPRPN Recombinant
 OPRPN Antibody
 BPLP ELISA Kit
 BPLP Recombinant
 BPLP Antibody
 PROL1 ELISA Kit
 PROL1 Recombinant
 PROL1 Antibody
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