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Origin recognition complex

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Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner (By similarity).

Below are the list of possible Origin recognition complex products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Origin recognition complex subunit 1

 Origin recognition complex subunit 1 ELISA Kit
 Origin recognition complex subunit 1 Recombinant
 Origin recognition complex subunit 1 Antibody
Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner ().
 ORC1 ELISA Kit
 ORC1 Recombinant
 ORC1 Antibody
 KLLA0B05016g ELISA Kit
 KLLA0B05016g Recombinant
 KLLA0B05016g Antibody
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Origin recognition complex subunit 2

 Origin recognition complex subunit 2 ELISA Kit
 Origin recognition complex subunit 2 Recombinant
 Origin recognition complex subunit 2 Antibody
ORC2: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. ORC is composed of six subunits. In human, ORC is cell cycle-dependent regulated: it
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is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with DBF4. Interacts with MCM10. Belongs to the ORC2 family.

Protein type: DNA replication

Cellular Component: centrosome; chromatin; heterochromatin; inner kinetochore of condensed chromosome; membrane; nuclear chromosome, telomeric region; nuclear origin of replication recognition complex; origin recognition complex

Molecular Function: DNA replication origin binding
 Orc2 ELISA Kit
 Orc2 Recombinant
 Orc2 Antibody
 Orc2l ELISA Kit
 Orc2l Recombinant
 Orc2l Antibody
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Origin recognition complex subunit 3

 Origin recognition complex subunit 3 ELISA Kit
 Origin recognition complex subunit 3 Recombinant
 Origin recognition complex subunit 3 Antibody
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (). Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 ().
 ORC3 ELISA Kit
 ORC3 Recombinant
 ORC3 Antibody
 ORC3L ELISA Kit
 ORC3L Recombinant
 ORC3L Antibody
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Origin recognition complex subunit 4

 Origin recognition complex subunit 4 ELISA Kit
 Origin recognition complex subunit 4 Recombinant
 Origin recognition complex subunit 4 Antibody
ORC4L: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Defects in ORC4 are the cause of Meier-Gorlin syndrome type 2 (MGORS2). MGORS2 is a
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syndrome characterized by bilateral microtia, aplasia/hypoplasia of the patellae, and severe intrauterine and postnatal growth retardation with short stature and poor weight gain. Additional clinical findings include anomalies of cranial sutures, microcephaly, apparently low-set and simple ears, microstomia, full lips, highly arched or cleft palate, micrognathia, genitourinary tract anomalies, and various skeletal anomalies. While almost all cases have primordial dwarfism with substantial prenatal and postnatal growth retardation, not all cases have microcephaly, and microtia and absent/hypoplastic patella are absent in some. Despite the presence of microcephaly, intellect is usually normal. Belongs to the ORC4 family.

Cellular Component: actin cytoskeleton; cytoplasm; nuclear chromosome, telomeric region; nuclear origin of replication recognition complex; nucleolus; nucleoplasm; nucleus; origin recognition complex

Molecular Function: DNA replication origin binding; nucleotide binding

Biological Process: DNA replication; DNA replication initiation
 Orc4 ELISA Kit
 Orc4 Recombinant
 Orc4 Antibody
 Orc4l ELISA Kit
 Orc4l Recombinant
 Orc4l Antibody
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Origin recognition complex subunit 5

 Origin recognition complex subunit 5 ELISA Kit
 Origin recognition complex subunit 5 Recombinant
 Origin recognition complex subunit 5 Antibody
ORC5L: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Belongs to the ORC5 family. 2 isoforms of the human protein are produced by alternat
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ive splicing.

Chromosomal Location of Human Ortholog: 7q22.1

Cellular Component: cytoplasm; nuclear chromosome, telomeric region; nuclear origin of replication recognition complex; nucleoplasm; nucleus; origin recognition complex

Molecular Function: DNA replication origin binding; nucleotide binding; protein binding

Biological Process: DNA replication; DNA replication initiation; G1/S transition of mitotic cell cycle
 ORC5 ELISA Kit
 ORC5 Recombinant
 ORC5 Antibody
 ORC5L ELISA Kit
 ORC5L Recombinant
 ORC5L Antibody
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Origin recognition complex subunit 6

 Origin recognition complex subunit 6 ELISA Kit
 Origin recognition complex subunit 6 Recombinant
 Origin recognition complex subunit 6 Antibody
ORC6L: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. ORC is composed of six subunits. In human, ORC is cell cycle-dependent regulated: it
>>>
is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with DBF4. Belongs to the ORC6 family.

Protein type: DNA replication

Chromosomal Location of Human Ortholog: 16q12

Cellular Component: actin cytoskeleton; membrane; nuclear origin of replication recognition complex; nucleoplasm; nucleus; origin recognition complex

Molecular Function: DNA replication origin binding; protein binding

Biological Process: DNA replication; DNA replication initiation; G1/S transition of mitotic cell cycle

Disease: Meier-gorlin Syndrome 3
 ORC6 ELISA Kit
 ORC6 Recombinant
 ORC6 Antibody
 ORC6L ELISA Kit
 ORC6L Recombinant
 ORC6L Antibody
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