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Ornithine decarboxylase antizyme

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Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

Below are the list of possible Ornithine decarboxylase antizyme products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Ornithine decarboxylase antizyme

 Ornithine decarboxylase antizyme ELISA Kit
 Ornithine decarboxylase antizyme Recombinant
 Ornithine decarboxylase antizyme Antibody
Mediates the degradation of SPE1 (ornithine decarboxylase) by the proteasome.
 OAZ1 ELISA Kit
 OAZ1 Recombinant
 OAZ1 Antibody
 CAGL0M07403g ELISA Kit
 CAGL0M07403g Recombinant
 CAGL0M07403g Antibody
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Ornithine decarboxylase antizyme 1

 Ornithine decarboxylase antizyme 1 ELISA Kit
 Ornithine decarboxylase antizyme 1 Recombinant
 Ornithine decarboxylase antizyme 1 Antibody
Also known as Ornithine decarboxylase antizyme 1 (ODC antizyme, short form) (ODC-Az-S).
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antiz
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ymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. Several antizyme paralogs have been described in zebrafish. The mRNA for this antizyme is ubiquitously expressed in the embryo and differentially expressed during development from embryo to adult fish. This antizyme shares features in common with mammalian antizyme 1: it negatively regulates intracellular polyamine levels by inhibiting ODC activity and accelerating ODC degradation in vitro; like mammalian antizyme 1 mRNA, this antizyme mRNA contains two potential in-frame translation initiation sites. [provided by RefSeq, Jan 2015]
 oaz1 ELISA Kit
 oaz1 Recombinant
 oaz1 Antibody
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Ornithine decarboxylase antizyme 2

 Ornithine decarboxylase antizyme 2 ELISA Kit
 Ornithine decarboxylase antizyme 2 Recombinant
 Ornithine decarboxylase antizyme 2 Antibody
Also known as Ornithine decarboxylase antizyme 2 (AZ2) (ODC-Az 2).
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamine in cells. Antizymes in turn bind to
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and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis pathway; thus, completing the auto-regulatory circuit. This gene encodes antizyme 2, the second member of the antizyme family. Like antizyme 1, antizyme 2 has broad tissue distribution, inhibits ODC activity and polyamine uptake, and stimulates ODC degradation in vivo, however, it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1, but is evolutionary more conserved, suggesting it likely has an important biological role. Studies also show different subcellular localization of antizymes 1 and 2, indicating specific function for each antizyme in discrete compartments of the cell. [provided by RefSeq, Aug 2014]
 OAZ2 ELISA Kit
 OAZ2 Recombinant
 OAZ2 Antibody
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Ornithine decarboxylase antizyme 3

 Ornithine decarboxylase antizyme 3 ELISA Kit
 Ornithine decarboxylase antizyme 3 Recombinant
 Ornithine decarboxylase antizyme 3 Antibody
Also known as Ornithine decarboxylase antizyme 3 (AZ3) (ODC-Az 3).
OAZ3: Isoform 2: Does not possess antizyme activity. Modulates PPP1CB activity through its interaction with PPP1R16A

Protein type: Inhibitor

Cellular Component: cytoplasm; nucleus

Molecular Function: ornithine decarboxylase inhibitor activity; putrescine transmembrane transporter activity

Biological P
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rocess: positive regulation of protein catabolic process; regulation of phosphoprotein phosphatase activity
 Oaz3 ELISA Kit
 Oaz3 Recombinant
 Oaz3 Antibody
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