| Oxygen-regulated protein 1 ELISA Kit|
Oxygen-regulated protein 1 Recombinant
Oxygen-regulated protein 1 Antibody
|Also known as Oxygen-regulated protein 1 (Retinitis pigmentosa 1 protein) (Retinitis pigmentosa RP1 protein). |
ORP1: Microtubule-associated protein regulating the stability and length of the microtubule-based axoneme of photoreceptors. Required for the differentiation of photoreceptor cells, it plays a role in the organization of the outer segment of rod and cone photoreceptors ensuring the corr
ect orientation and higher-order stacking of outer segment disks along the photoreceptor axoneme. Defects in RP1 are the cause of retinitis pigmentosa type 1 (RP1). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 8q12.1
Cellular Component: axoneme; microtubule associated complex; photoreceptor connecting cilium; photoreceptor inner segment; photoreceptor outer segment
Molecular Function: microtubule binding; protein binding
Biological Process: axoneme biogenesis; photoreceptor cell development; photoreceptor cell maintenance; phototransduction, visible light; retina development in camera-type eye; retinal cone cell development; retinal rod cell development
Disease: Retinitis Pigmentosa 1
| RP1 ELISA Kit|
| ORP1 ELISA Kit|