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P2X purinoceptor

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Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death (By similarity).

Below are the list of possible P2X purinoceptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

P2X purinoceptor 1

 P2X purinoceptor 1 ELISA Kit
 P2X purinoceptor 1 Recombinant
 P2X purinoceptor 1 Antibody
Also known as P2X purinoceptor 1 (P2X1) (ATP receptor) (Purinergic receptor).
P2X1: Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death.
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Belongs to the P2X receptor family.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: integral to nuclear inner membrane; plasma membrane

Molecular Function: cation channel activity; purinergic nucleotide receptor activity

Biological Process: blood coagulation; ion transport; signal transduction; transport

Disease: Bleeding Disorder, Platelet-type, 8
 P2RX1 ELISA Kit
 P2RX1 Recombinant
 P2RX1 Antibody
 P2X1 ELISA Kit
 P2X1 Recombinant
 P2X1 Antibody
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P2X purinoceptor 2

 P2X purinoceptor 2 ELISA Kit
 P2X purinoceptor 2 Recombinant
 P2X purinoceptor 2 Antibody
Also known as P2X purinoceptor 2 (P2X2) (ATP receptor) (Purinergic receptor).
P2X2: Binding of this ligand-gated ion channel to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Belongs to the P2X receptor family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, cation; Channel, ligand-gated; Membrane protein
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, integral; Membrane protein, multi-pass

Cellular Component: apical plasma membrane; cell soma; cell surface; dendritic spine; integral to membrane; integral to nuclear inner membrane; integral to plasma membrane; intracellular; membrane; plasma membrane; postsynaptic density; presynaptic membrane; receptor complex; terminal button

Molecular Function: ATP binding; ATP-gated cation channel activity; cadmium ion binding; cobalt ion binding; copper ion binding; drug binding; identical protein binding; ligand-gated ion channel activity; mercury ion binding; nickel ion binding; phosphoinositide binding; protein binding; purinergic nucleotide receptor activity; zinc ion binding

Biological Process: behavioral response to pain; detection of hypoxic conditions in blood by carotid body chemoreceptors; generation of action potential; neuromuscular junction development; neuromuscular synaptic transmission; peristalsis; protein heterooligomerization; protein homooligomerization; response to ATP; response to carbohydrate stimulus; response to hypoxia; response to organic substance; sensory perception of sound; sensory perception of taste; skeletal muscle fiber development; synaptic transmission; urinary bladder smooth muscle contraction
 P2rx2 ELISA Kit
 P2rx2 Recombinant
 P2rx2 Antibody
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P2X purinoceptor 3

 P2X purinoceptor 3 ELISA Kit
 P2X purinoceptor 3 Recombinant
 P2X purinoceptor 3 Antibody
Also known as P2X purinoceptor 3 (P2X3) (ATP receptor) (Purinergic receptor).
P2X3: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11q12

Cellular Component: integral to nuclear inner membrane; pl
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asma membrane; receptor complex

Molecular Function: purinergic nucleotide receptor activity

Biological Process: blood coagulation; signal transduction; transport
 P2RX3 ELISA Kit
 P2RX3 Recombinant
 P2RX3 Antibody
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P2X purinoceptor 4

 P2X purinoceptor 4 ELISA Kit
 P2X purinoceptor 4 Recombinant
 P2X purinoceptor 4 Antibody
Also known as P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor).
Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin ().
 P2RX4 ELISA Kit
 P2RX4 Recombinant
 P2RX4 Antibody
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P2X purinoceptor 5

 P2X purinoceptor 5 ELISA Kit
 P2X purinoceptor 5 Recombinant
 P2X purinoceptor 5 Antibody
Also known as P2X purinoceptor 5 (P2X5) (ATP receptor) (Purinergic receptor).
P2X5: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 17p13.3

Cellular
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Component: cytoplasm; integral to nuclear inner membrane; plasma membrane

Molecular Function: ATP-gated cation channel activity; ion channel activity; purinergic nucleotide receptor activity; transmembrane receptor activity

Biological Process: blood coagulation; nervous system development; signal transduction; transport
 P2RX5 ELISA Kit
 P2RX5 Recombinant
 P2RX5 Antibody
 P2X5 ELISA Kit
 P2X5 Recombinant
 P2X5 Antibody
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P2X purinoceptor 6

 P2X purinoceptor 6 ELISA Kit
 P2X purinoceptor 6 Recombinant
 P2X purinoceptor 6 Antibody
Also known as P2X purinoceptor 6 (P2X6) (ATP receptor) (P2XM) (Purinergic receptor) (Purinergic receptor P2X-like 1).
acts as an ATP-gated ion channel [RGD, Feb 2006]
 P2rx6 ELISA Kit
 P2rx6 Recombinant
 P2rx6 Antibody
 P2rxl1 ELISA Kit
 P2rxl1 Recombinant
 P2rxl1 Antibody
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P2X purinoceptor 7

 P2X purinoceptor 7 ELISA Kit
 P2X purinoceptor 7 Recombinant
 P2X purinoceptor 7 Antibody
Also known as P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor).
P2X7: a receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis by macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coup
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led to changes in gene expression. Alternatively spliced variants encoding different isoforms have been identified. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. Phosphorylation results in its inactivation.

Protein type: Channel, ligand-gated; Membrane protein, integral; Membrane protein, multi-pass; Receptor, misc.

Chromosomal Location of Human Ortholog: 12q24

Cellular Component: cytoplasm; integral to nuclear inner membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: ATP binding; ATP-gated cation channel activity; lipopolysaccharide binding; protein binding; purinergic nucleotide receptor activity; receptor binding

Biological Process: bleb formation; blood coagulation; cell surface receptor linked signal transduction; membrane depolarization; negative regulation of bone resorption; negative regulation of cell volume; negative regulation of MAPKKK cascade; phospholipid scrambling; pore complex biogenesis; positive regulation of bone mineralization; positive regulation of cytolysis; positive regulation of cytoskeleton organization and biogenesis; positive regulation of glycolysis; positive regulation of interleukin-1 beta secretion; regulation of sodium ion transport; response to ATP; sensory perception of pain

Disease: Leukemia, Chronic Lymphocytic
 P2RX7 ELISA Kit
 P2RX7 Recombinant
 P2RX7 Antibody
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