| Paired immunoglobulin-like type 2 receptor alpha ELISA Kit|
Paired immunoglobulin-like type 2 receptor alpha Recombinant
Paired immunoglobulin-like type 2 receptor alpha Antibody
|Also known as Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha). |
PILRA: Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SH
P-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.
Cellular Component: integral to plasma membrane
Molecular Function: MHC class I protein binding; protein binding
Biological Process: signal transduction; transmembrane receptor protein tyrosine kinase signaling pathway
| Pilra ELISA Kit|