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Paired mesoderm homeobox protein

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May participate in maintenance of mesenchymal cell lineages derived from both mesoderm and the neural crest and in patterning of the limbs and the face.

Below are the list of possible Paired mesoderm homeobox protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Paired mesoderm homeobox protein 1

 Paired mesoderm homeobox protein 1 ELISA Kit
 Paired mesoderm homeobox protein 1 Recombinant
 Paired mesoderm homeobox protein 1 Antibody
Also known as Paired mesoderm homeobox protein 1 (GMHOX) (Homeobox protein MHOX) (Paired-related homeobox protein 1) (PRX-1).
May participate in maintenance of mesenchymal cell lineages derived from both mesoderm and the neural crest and in patterning of the limbs and the face.
 PRRX1 ELISA Kit
 PRRX1 Recombinant
 PRRX1 Antibody
 MHOX ELISA Kit
 MHOX Recombinant
 MHOX Antibody
 PMX1 ELISA Kit
 PMX1 Recombinant
 PMX1 Antibody
 PRX1 ELISA Kit
 PRX1 Recombinant
 PRX1 Antibody
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Paired mesoderm homeobox protein 2

 Paired mesoderm homeobox protein 2 ELISA Kit
 Paired mesoderm homeobox protein 2 Recombinant
 Paired mesoderm homeobox protein 2 Antibody
Also known as Paired mesoderm homeobox protein 2 (Paired-related homeobox protein 2) (PRX-2).
PRRX2: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Belongs to the paired homeobox family.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 9q34.1
 PRRX2 ELISA Kit
 PRRX2 Recombinant
 PRRX2 Antibody
 PMX2 ELISA Kit
 PMX2 Recombinant
 PMX2 Antibody
 PRX2 ELISA Kit
 PRX2 Recombinant
 PRX2 Antibody
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Paired mesoderm homeobox protein 2A

 Paired mesoderm homeobox protein 2A ELISA Kit
 Paired mesoderm homeobox protein 2A Recombinant
 Paired mesoderm homeobox protein 2A Antibody
Also known as Paired mesoderm homeobox protein 2A (Aristaless homeobox protein homolog) (PHOX2A homeodomain protein) (Paired-like homeobox 2A).
PHOX2A: May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype. Defects in PHOX2A are the cause of congenital fibrosis of extraocular muscles type 2 (CFEOM2). CFEOM encompasses several different inherited strabismus syndromes characterized by congenital restrictive ophthalmoplegia affecting extraocular muscles innervated
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by the oculomotor and/or trochlear nerves. CFEOM is characterized clinically by anchoring of the eyes in downward gaze, ptosis, and backward tilt of the head. CFEOM2 may result from the aberrant development of the oculomotor (nIII), trochlear (nIV) and abducens (nVI) cranial nerve nuclei. Belongs to the paired homeobox family.

Protein type: DNA-binding; Transcription factor

Cellular Component: nuclear chromatin; nucleus

Biological Process: locus ceruleus development; midbrain development; oculomotor nerve formation; parasympathetic nervous system development; positive regulation of transcription from RNA polymerase II promoter; regulation of respiratory gaseous exchange; somatic motor neuron differentiation; sympathetic nervous system development; trochlear nerve formation
 Phox2a ELISA Kit
 Phox2a Recombinant
 Phox2a Antibody
 Arix ELISA Kit
 Arix Recombinant
 Arix Antibody
 Phox2 ELISA Kit
 Phox2 Recombinant
 Phox2 Antibody
 Pmx2 ELISA Kit
 Pmx2 Recombinant
 Pmx2 Antibody
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Paired mesoderm homeobox protein 2B

 Paired mesoderm homeobox protein 2B ELISA Kit
 Paired mesoderm homeobox protein 2B Recombinant
 Paired mesoderm homeobox protein 2B Antibody
Also known as Paired mesoderm homeobox protein 2B (Neuroblastoma Phox) (NBPhox) (PHOX2B homeodomain protein) (Paired-like homeobox 2B).
PHOX2B: Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the do
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pamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum- response element. Defects in PHOX2B are a cause of congenital central hypoventilation syndrome (CCHS); also known as congenital failure of autonomic control or Ondine curse. Most mutations consist of 5-10 alanine expansions in the poly-Ala region from amino acids 241-260. CCHS is a rare disorder characterized by abnormal control of respiration in the absence of neuromuscular or lung disease, or an identifiable brain stem lesion. A deficiency in autonomic control of respiration results in inadequate or negligible ventilatory and arousal responses to hypercapnia and hypoxemia. CCHS is frequently complicated with neurocristopathies such as Hirschsprung disease that occurs in about 16% of CCHS cases. Defects in PHOX2B are the cause of susceptibility to neuroblastoma type 2 (NBLST2). A common neoplasm of early childhood arising from embryonic cells that form the primitive neural crest and give rise to the adrenal medulla and the sympathetic nervous system. Belongs to the paired homeobox family.

Protein type: DNA-binding; Transcription regulation

Chromosomal Location of Human Ortholog: 4p12

Cellular Component: nuclear chromatin

Biological Process: autonomic nervous system development; cell differentiation in hindbrain; efferent axon development in a lateral line nerve; enteric nervous system development; glial cell differentiation; hindbrain tangential cell migration; inner ear development; neurological control of breathing; neuron migration; parasympathetic nervous system development; positive regulation of transcription from RNA polymerase II promoter; regulation of gene expression; rhombencephalic reticular formation development; sympathetic nervous system development

Disease: Central Hypoventilation Syndrome, Congenital; Neuroblastoma, Susceptibility To, 2
 PHOX2B ELISA Kit
 PHOX2B Recombinant
 PHOX2B Antibody
 PMX2B ELISA Kit
 PMX2B Recombinant
 PMX2B Antibody
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