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Pancreas/duodenum homeobox protein

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Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3' (By similarity).

Below are the list of possible Pancreas/duodenum homeobox protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pancreas/duodenum homeobox protein 1

 Pancreas/duodenum homeobox protein 1 ELISA Kit
 Pancreas/duodenum homeobox protein 1 Recombinant
 Pancreas/duodenum homeobox protein 1 Antibody
Also known as Pancreas/duodenum homeobox protein 1 (Homeodomain protein PDX1) (Insulin promoter factor 1) (IPF-1).
Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut.
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As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3' ().
 PDX1 ELISA Kit
 PDX1 Recombinant
 PDX1 Antibody
 IPF1 ELISA Kit
 IPF1 Recombinant
 IPF1 Antibody
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