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Pantothenate kinase 4 ELISA Kit Pantothenate kinase 4 Recombinant Pantothenate kinase 4 Antibody | Also known as Pantothenate kinase 4 (hPanK4) (Pantothenic acid kinase 4). PANK4: a pantothenate kinase that catalyzes the first committed step in the biosynthesis of coenzyme A, an essential cofactor in cellular metabolism. PANK4 is ubiquitously expressed but is enriched in muscle. Plays a role in the physiological regulation of the intracellular CoA concentration. Regulated by feedback inhibit >>> ion by CoA and its thioesters. Interacts with M2-type pyruvate kinase (PKM2) and may modulate glucose metabolism through regulating the activity of PKM2. Expression is up-regulated by high glucose concentrations.
Protein type: Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.7.1.33; Kinase, other
Chromosomal Location of Human Ortholog: 1p36.32 |
PANK4 ELISA Kit PANK4 Recombinant PANK4 Antibody |
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