Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow PC4 and SFRS1-interacting protein  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Paxillin (Ab-178) (PXN) Antibody
 • PAK1-2-3 (Phospho-Ser144-141-139) Antibody
 • HINT1 Antibody
 • OR4C3 Antibody
 • Apolipoprotein M (APOM) ELISA Kit
 • Anthrax Protective Antigen IgG (APA IgG) ELISA Kit
 • Protectin (CD59) ELISA Kit
 • Glucocorticoid Receptor-alpha (GR-alpha) ELISA Kit
 • Phosphorylated Oncogene Protein P190-BCR-ABL (p-OPP190-p-BCR... ELISA Kit
 • beta Enkephalin (beta-ENK) ELISA Kit
 • Intrinsic Factor Antibody (IF) ELISA Kit
 • Second Mitochondrial-Derived Activator of Caspase (SMAC) ELISA Kit
 • Centriole and Centrosome Antibody IgG (ACA-IgG) ELISA Kit
 • Growth Factor Receptor Bound Protein 10 (GRB10) ELISA Kit
 downarrow more ...
separator

PC4 and SFRS1-interacting protein

separator
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Below are the list of possible PC4 and SFRS1-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

PC4 and SFRS1-interacting protein

 PC4 and SFRS1-interacting protein ELISA Kit
 PC4 and SFRS1-interacting protein Recombinant
 PC4 and SFRS1-interacting protein Antibody
Also known as PC4 and SFRS1-interacting protein (CLL-associated antigen KW-7) (Dense fine speckles 70 kDa protein) (DFS 70) (Lens epithelium-derived growth factor) (Transcriptional coactivator p75/p52).
LEDGF: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional
>>>
coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Monomer. Interacts with IFRD1/PC4. Isoform 2 interacts with SFRS1. Isoform 1 interacts POGZ and CDCA7L. Isoform 1 interacts with lentiviral integrase and acts as a chromatin tethering factor to the chromosomal DNA. Isoform 1 interacts in particular with the human HIV-1 integrase protein (HIV-1 IN), determining its nuclear localization, its tight association with chromatin and its protection from the proteasome. Isoform 1 interacts also with HIV-2 IN. Isoform 2 does not interact with HIV-1 IN. Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. Belongs to the HDGF family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 9p22.3

Cellular Component: cytosol; nucleoplasm

Molecular Function: protein binding

Biological Process: nuclear mRNA 5'-splice site recognition; nuclear transport; response to heat; response to oxidative stress
 PSIP1 ELISA Kit
 PSIP1 Recombinant
 PSIP1 Antibody
 DFS70 ELISA Kit
 DFS70 Recombinant
 DFS70 Antibody
 LEDGF ELISA Kit
 LEDGF Recombinant
 LEDGF Antibody
 PSIP2 ELISA Kit
 PSIP2 Recombinant
 PSIP2 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions