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PE family protein

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Together with PE9, induces macrophage apoptosis through human Toll-like receptor 4 (TLR4) signaling pathway. Interaction with TLR4 leads to increased levels of phospho-IRF-3, increase in the transcript levels of IFN-beta and pro-apoptotic genes, up-regulation of IL-10, down-regulation of IL-1b and enhanced levels of macrophage apoptosis.

Below are the list of possible PE family protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

PE family protein PE10

 PE family protein PE10 ELISA Kit
 PE family protein PE10 Recombinant
 PE family protein PE10 Antibody
Together with PE9, induces macrophage apoptosis through human Toll-like receptor 4 (TLR4) signaling pathway. Interaction with TLR4 leads to increased levels of phospho-IRF-3, increase in the transcript levels of IFN-beta and pro-apoptotic genes, up-regulation of IL-10, down-regulation of IL-1b and enhanced levels of macrophage apoptosis.
 PE10 ELISA Kit
 PE10 Recombinant
 PE10 Antibody
 Rv1089 ELISA Kit
 Rv1089 Recombinant
 Rv1089 Antibody
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PE family protein PE13

 PE family protein PE13 ELISA Kit
 PE family protein PE13 Recombinant
 PE family protein PE13 Antibody
May play a pivotal role in the interaction between M.tuberculosis and host. Can enhance the survival within macrophages under stress conditions such as H2O2, SDS and low pH. Increases the production of IL-6 and IL-1beta from macrophages, and decreases the secretion of suppressor of cytokine signaling 3 (SOCS-3). These changes probably involve the p38-ERK-NF-kappa-B signaling pathway. Also precipitates the macrophage death.
 PE13 ELISA Kit
 PE13 Recombinant
 PE13 Antibody
 Rv1195 ELISA Kit
 Rv1195 Recombinant
 Rv1195 Antibody
 LH57_06555 ELISA Kit
 LH57_06555 Recombinant
 LH57_06555 Antibody
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PE family protein PE3

 PE family protein PE3 ELISA Kit
 PE family protein PE3 Recombinant
 PE family protein PE3 Antibody
Plays significant roles in mycobacterial persistence during infection and modulates host immune response.
 PE3 ELISA Kit
 PE3 Recombinant
 PE3 Antibody
 Rv0159c ELISA Kit
 Rv0159c Recombinant
 Rv0159c Antibody
 LH57_00895 ELISA Kit
 LH57_00895 Recombinant
 LH57_00895 Antibody
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PE family protein PE9

 PE family protein PE9 ELISA Kit
 PE family protein PE9 Recombinant
 PE family protein PE9 Antibody
Together with PE10, induces macrophage apoptosis through human Toll-like receptor 4 (TLR4) signaling pathway. Interaction with TLR4 leads to increased levels of phospho-IRF-3, increase in the transcript levels of IFN-beta and pro-apoptotic genes, up-regulation of IL-10, down-regulation of IL-1b and enhanced levels of macrophage apoptosis.
 PE9 ELISA Kit
 PE9 Recombinant
 PE9 Antibody
 Rv1088 ELISA Kit
 Rv1088 Recombinant
 Rv1088 Antibody
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