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PE-PGRS family protein

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Induces maturation and activation of human dendritic cells (DCs), via TLR2-dependent activation of ERK1/2, p38 MAPK, and NF-kappa-B signaling pathways, and enhances the ability of DCs to stimulate CD4(+) T cells. By activating DCs, could potentially contribute to the initiation of innate immune responses during tuberculosis infection and hence regulate the clinical course of tuberculosis .

Below are the list of possible PE-PGRS family protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

PE-PGRS family protein PE_PGRS11

 PE-PGRS family protein PE_PGRS11 ELISA Kit
 PE-PGRS family protein PE_PGRS11 Recombinant
 PE-PGRS family protein PE_PGRS11 Antibody
Also known as PE-PGRS family protein PE_PGRS11 (PE-PGRS phosphoglycerate mutase).
Induces maturation and activation of human dendritic cells (DCs), via TLR2-dependent activation of ERK1/2, p38 MAPK, and NF-kappa-B signaling pathways, and enhances the ability of DCs to stimulate CD4+ T cells. By activating DCs, could potentially contribute to the initiation of innate immune responses during tube
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rculosis infection and hence regulate the clinical course of tuberculosis (PubMed:20176745). Involved in resistance to oxidative stress, via TLR2-dependent activation of the PI3K-ERK1/2-NF-kappa-B signaling pathway and expression of COX-2 and Bcl2. Also abolishes H2O(2)-triggered activation of p38 MAPK (PubMed:20558725).
 PE_PGRS11 ELISA Kit
 PE_PGRS11 Recombinant
 PE_PGRS11 Antibody
 Rv0754 ELISA Kit
 Rv0754 Recombinant
 Rv0754 Antibody
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PE-PGRS family protein PE_PGRS16

 PE-PGRS family protein PE_PGRS16 ELISA Kit
 PE-PGRS family protein PE_PGRS16 Recombinant
 PE-PGRS family protein PE_PGRS16 Antibody
 PE_PGRS16 ELISA Kit
 PE_PGRS16 Recombinant
 PE_PGRS16 Antibody
 Rv0977 ELISA Kit
 Rv0977 Recombinant
 Rv0977 Antibody
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PE-PGRS family protein PE_PGRS17

 PE-PGRS family protein PE_PGRS17 ELISA Kit
 PE-PGRS family protein PE_PGRS17 Recombinant
 PE-PGRS family protein PE_PGRS17 Antibody
Induces maturation and activation of human dendritic cells (DCs), via TLR2-dependent activation of ERK1/2, p38 MAPK, and NF-kappa-B signaling pathways, and enhances the ability of DCs to stimulate CD4+ T cells. By activating DCs, could potentially contribute to the initiation of innate immune responses during tuberculosis infection and hence regulate the clinical course of tuberculosis.
 PE_PGRS17 ELISA Kit
 PE_PGRS17 Recombinant
 PE_PGRS17 Antibody
 Rv0978c ELISA Kit
 Rv0978c Recombinant
 Rv0978c Antibody
 LH57_05330 ELISA Kit
 LH57_05330 Recombinant
 LH57_05330 Antibody
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PE-PGRS family protein PE_PGRS18

 PE-PGRS family protein PE_PGRS18 ELISA Kit
 PE-PGRS family protein PE_PGRS18 Recombinant
 PE-PGRS family protein PE_PGRS18 Antibody
Enzyme and pathway databasesBioCyc Collection of Pathway/Genome Databases<br/><a href='/database/5'>More..</a>BioCyciMTBH37RV:G185E-5137-MONOMER.
 PE_PGRS18 ELISA Kit
 PE_PGRS18 Recombinant
 PE_PGRS18 Antibody
 Rv0980c ELISA Kit
 Rv0980c Recombinant
 Rv0980c Antibody
 LH57_05345 ELISA Kit
 LH57_05345 Recombinant
 LH57_05345 Antibody
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PE-PGRS family protein PE_PGRS26

 PE-PGRS family protein PE_PGRS26 ELISA Kit
 PE-PGRS family protein PE_PGRS26 Recombinant
 PE-PGRS family protein PE_PGRS26 Antibody
Enzyme and pathway databasesBioCyc Collection of Pathway/Genome Databases<br/><a href='/database/5'>More..</a>BioCyciMTBH37RV:G185E-5624-MONOMER.
 PE_PGRS26 ELISA Kit
 PE_PGRS26 Recombinant
 PE_PGRS26 Antibody
 Rv1441c ELISA Kit
 Rv1441c Recombinant
 Rv1441c Antibody
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PE-PGRS family protein PE_PGRS30

 PE-PGRS family protein PE_PGRS30 ELISA Kit
 PE-PGRS family protein PE_PGRS30 Recombinant
 PE-PGRS family protein PE_PGRS30 Antibody
Mediates suppression of proinflammatory immune response in macrophages via modulation of host cytokine response (PubMed:27129781). Required for full virulence. Involved in inhibition of phago-lysosome fusion (PubMed:22050772).
 PE_PGRS30 ELISA Kit
 PE_PGRS30 Recombinant
 PE_PGRS30 Antibody
 Rv1651c ELISA Kit
 Rv1651c Recombinant
 Rv1651c Antibody
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PE-PGRS family protein PE_PGRS33

 PE-PGRS family protein PE_PGRS33 ELISA Kit
 PE-PGRS family protein PE_PGRS33 Recombinant
 PE-PGRS family protein PE_PGRS33 Antibody
Induces TNF-alpha release through human Toll-like receptor 2 (TLR2) signaling pathway, leading to macrophage apoptosis (PubMed:17095513, PubMed:17223373, PubMed:24106104). The signaling pathway involves TLR2-dependent activation of the mitogen-activated protein kinase kinase kinase 5 (ASK1), which activates the p38 and JNK MAPKs, leading to enhanced expression of TNF-alpha and tumor necrosis factor receptor superfamily member 1A (TNFRI) genes. Signals are amplified through classical caspase 8-dependent mitochondrial release of cytochrome c, leading to the activation of caspases 9 and 3 (PubMed
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:17095513). Mediates Ca2+-dependent up-regulation of the anti-inflammatory cytokine IL-10 (PubMed:27483162). Mediates entry into macrophages in a TLR2-dependent mechanism and activates the TLR2-dependent pro-adhesive pathway (PubMed:26978522).
 PE_PGRS33 ELISA Kit
 PE_PGRS33 Recombinant
 PE_PGRS33 Antibody
 Rv1818c ELISA Kit
 Rv1818c Recombinant
 Rv1818c Antibody
 MTCY1A11.25c ELISA Kit
 MTCY1A11.25c Recombinant
 MTCY1A11.25c Antibody
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PE-PGRS family protein PE_PGRS47

 PE-PGRS family protein PE_PGRS47 ELISA Kit
 PE-PGRS family protein PE_PGRS47 Recombinant
 PE-PGRS family protein PE_PGRS47 Antibody
Contributes to evasion of both innate and adaptive immunity. Inhibits autophagy in infected host phagocytes and inhibits major histocompatibility complex (MHC) class II antigen presentation by mycobacteria-infected dendritic cells. Has an important role in the growth and survival of M.tuberculosis, particularly during intracellular growth and in the later chronic phase of infection.
 PE_PGRS47 ELISA Kit
 PE_PGRS47 Recombinant
 PE_PGRS47 Antibody
 Rv2741 ELISA Kit
 Rv2741 Recombinant
 Rv2741 Antibody
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PE-PGRS family protein PE_PGRS60

 PE-PGRS family protein PE_PGRS60 ELISA Kit
 PE-PGRS family protein PE_PGRS60 Recombinant
 PE-PGRS family protein PE_PGRS60 Antibody
Binds fibronectin. May contribute to pathogenicity.
 PE_PGRS60 ELISA Kit
 PE_PGRS60 Recombinant
 PE_PGRS60 Antibody
 Rv3652 ELISA Kit
 Rv3652 Recombinant
 Rv3652 Antibody
 LH57_19900 ELISA Kit
 LH57_19900 Recombinant
 LH57_19900 Antibody
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PE-PGRS family protein PE_PGRS61

 PE-PGRS family protein PE_PGRS61 ELISA Kit
 PE-PGRS family protein PE_PGRS61 Recombinant
 PE-PGRS family protein PE_PGRS61 Antibody
Mediates Ca2+-dependent up-regulation of the anti-inflammatory cytokine IL-10.
 PE_PGRS61 ELISA Kit
 PE_PGRS61 Recombinant
 PE_PGRS61 Antibody
 Rv3653 ELISA Kit
 Rv3653 Recombinant
 Rv3653 Antibody
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PE-PGRS family protein PE_PGRS8

 PE-PGRS family protein PE_PGRS8 ELISA Kit
 PE-PGRS family protein PE_PGRS8 Recombinant
 PE-PGRS family protein PE_PGRS8 Antibody
Enzyme and pathway databasesBioCyc Collection of Pathway/Genome Databases<br/><a href='/database/5'>More..</a>BioCyciMTBH37RV:G185E-4887-MONOMER.
 PE_PGRS8 ELISA Kit
 PE_PGRS8 Recombinant
 PE_PGRS8 Antibody
 Rv0742 ELISA Kit
 Rv0742 Recombinant
 Rv0742 Antibody
 LH57_04020 ELISA Kit
 LH57_04020 Recombinant
 LH57_04020 Antibody
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PE-PGRS family protein PE25

 PE-PGRS family protein PE25 ELISA Kit
 PE-PGRS family protein PE25 Recombinant
 PE-PGRS family protein PE25 Antibody
The PE25/PPE41 dimer induces both a strong humoral and cellular immune response. PE25 protein alone induces low response (PubMed:18974870). The dimer induces necrosis, but not apoptosis, in mouse macrophage cells (PubMed:25379378). It also induces activation and maturation of mouse dendritic cells and drives Th2-biased immune responses (PubMed:26318856).
 PE25 ELISA Kit
 PE25 Recombinant
 PE25 Antibody
 Rv2431c ELISA Kit
 Rv2431c Recombinant
 Rv2431c Antibody
 LH57_13295 ELISA Kit
 LH57_13295 Recombinant
 LH57_13295 Antibody
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Proteins Root Name Listing
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