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Pendrin

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Sodium-independent transporter of chloride and iodide.

Below are the list of possible Pendrin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pendrin

 Pendrin ELISA Kit
 Pendrin Recombinant
 Pendrin Antibody
Also known as Pendrin (Sodium-independent chloride/iodide transporter) (Solute carrier family 26 member 4).
SLC26A4: Sodium-independent transporter of chloride and iodide. Defects in SLC26A4 are a cause of Pendred syndrome (PDS). PDS is an autosomal recessive disorder characterized by congenital sensorineural hearing loss combined with thyroid goiter. The disorder may account for up to 10% of t
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he cases of hereditary deafness. The deafness is most often associated with a Mondini cochlear defect. Defects in SLC26A4 are the cause of deafness autosomal recessive type 4 (DFNB4); also known as vestibular aqueduct syndrome (EVA). DFNB4 is a form of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to the brain, or the area of the brain that receives sound information. DFNB4 is associated with an enlarged vestibular aqueduct. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: apical plasma membrane; brush border membrane; integral to plasma membrane

Molecular Function: anion transmembrane transporter activity; anion:anion antiporter activity; bicarbonate transmembrane transporter activity; chloride channel activity; chloride transmembrane transporter activity; iodide transmembrane transporter activity; oxalate transmembrane transporter activity; sulfate transmembrane transporter activity

Biological Process: bicarbonate transport; inorganic anion transport; organ morphogenesis; regulation of intracellular pH; regulation of membrane potential; regulation of pH; regulation of protein localization
 Slc26a4 ELISA Kit
 Slc26a4 Recombinant
 Slc26a4 Antibody
 Pds ELISA Kit
 Pds Recombinant
 Pds Antibody
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