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Pericentrin

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Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome.

Below are the list of possible Pericentrin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pericentrin

 Pericentrin ELISA Kit
 Pericentrin Recombinant
 Pericentrin Antibody
PCNT: Integral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inh
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ibiting NEK2 kinase activity at the centrosome. Defects in PCNT are the cause of microcephalic osteodysplastic primordial dwarfism type 2 (MOPD2); also known as osteodysplastic primordial dwarfism type 2. Adults with this rare inherited condition have an average height of 100 centimeters and a brain size comparable to that of a 3-month-old baby, but are of near-normal intelligence. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Cellular Component: centriole; centrosome; cis-Golgi network; intercellular bridge; microtubule organizing center; pericentriolar material

Molecular Function: protein binding

Biological Process: brain morphogenesis; camera-type eye development; cerebellar cortex morphogenesis; embryonic heart tube development; in utero embryonic development; kidney development; limb morphogenesis; mitotic spindle organization and biogenesis; multicellular organism growth; negative regulation of apoptosis; neuron migration; olfactory bulb development; spindle organization and biogenesis; vasculature development
 Pcnt ELISA Kit
 Pcnt Recombinant
 Pcnt Antibody
 Pcnt2 ELISA Kit
 Pcnt2 Recombinant
 Pcnt2 Antibody
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