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Persulfide dioxygenase

Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) gives rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase. Required for normal endosperm development in seed, and thereby also required for normal embryo development.

Below are the list of possible Persulfide dioxygenase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Persulfide dioxygenase ETHE1 homolog

 Persulfide dioxygenase ETHE1 homolog ELISA Kit
 Persulfide dioxygenase ETHE1 homolog Recombinant
 Persulfide dioxygenase ETHE1 homolog Antibody
Also known as Persulfide dioxygenase ETHE1 homolog, mitochondrial (Glyoxalase II) (Glx II) (Sulfur dioxygenase ETHE1).
Mononuclear Fe(II)-containing member of the b-lactamase fold superfamily. ETHE1 is homodimeric in solution, exhibits low-level esterase activity, and specifically binds a single Fe(II) atom in the active site.
 GLY3 Recombinant
 GLY3 Antibody
 At1g53580 ELISA Kit
 At1g53580 Recombinant
 At1g53580 Antibody
 F22G10.9 ELISA Kit
 F22G10.9 Recombinant
 F22G10.9 Antibody
 T3F20.11 ELISA Kit
 T3F20.11 Recombinant
 T3F20.11 Antibody
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Persulfide dioxygenase ETHE1

 Persulfide dioxygenase ETHE1 ELISA Kit
 Persulfide dioxygenase ETHE1 Recombinant
 Persulfide dioxygenase ETHE1 Antibody
Also known as Persulfide dioxygenase ETHE1, mitochondrial (Ethylmalonic encephalopathy protein 1 homolog) (Hepatoma subtracted clone one protein) (Sulfur dioxygenase ETHE1).
ETHE1: Probably plays an important role in metabolic homeostasis in mitochondria. May function as a nuclear-cytoplasmic shuttling protein that binds transcription factor RELA/NFKB3 in the nucleus and exports it to the cytop
lasm. Suppresses p53- induced apoptosis by preventing nuclear localization of RELA. Defects in ETHE1 are a cause of ethylmalonic encephalopathy (EE). EE is an autosomal recessive disorder characterized by neurodevelopmental delay and regression, recurrent petechiae, acrocyanosis, diarrhea, leading to death in the first decade of life. It is also associated with persistent lactic acidemia and ethylmalonic and methylsuccinic aciduria. Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

Protein type: EC; Hydrolase; Mitochondrial

Cellular Component: cytoplasm; mitochondrion; nucleoplasm

Molecular Function: iron ion binding; sulfur dioxygenase activity

Biological Process: glutathione metabolic process
 Ethe1 ELISA Kit
 Ethe1 Recombinant
 Ethe1 Antibody
 Hsco ELISA Kit
 Hsco Recombinant
 Hsco Antibody
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