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Phosphate-regulating neutral endopeptidase

Probably involved in bone and dentin mineralization and renal phosphate reabsorption.

Below are the list of possible Phosphate-regulating neutral endopeptidase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Phosphate-regulating neutral endopeptidase

 Phosphate-regulating neutral endopeptidase ELISA Kit
 Phosphate-regulating neutral endopeptidase Recombinant
 Phosphate-regulating neutral endopeptidase Antibody
Also known as Phosphate-regulating neutral endopeptidase (Metalloendopeptidase homolog PEX) (Vitamin D-resistant hypophosphatemic rickets protein) (X-linked hypophosphatemia protein) (HYP).
PHEX: Probably involved in bone and dentin mineralization and renal phosphate reabsorption. Defects in PHEX are a cause of hypophosphatemic rickets, X-linked dominant (XLHR). XLHR is an X-linked dominant dis
order characterized by impaired phosphate uptake in the kidney, which is likely to be caused by abnormal regulation of sodium phosphate cotransport in the proximal tubules. Clinical manifestations include skeletal deformities, growth failure, craniosynostosis, paravertebral calcifications, pseudofractures in lower extremities, and muscular hypotonia with onset in early childhood. X-linked hypophosphatemic rickets is the most common form of hypophosphatemia with an incidence of 1 in 20000. Belongs to the peptidase M13 family.

Protein type: EC 3.4.24.-; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: Xp22.2-p22.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: zinc ion binding

Biological Process: cell-cell signaling; protein modification process; proteolysis; skeletal development

Disease: Hypophosphatemic Rickets, X-linked Dominant
 PHEX Recombinant
 PHEX Antibody
 PEX Recombinant
 PEX Antibody
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