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Phosphatidate phosphatase

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Mg(2+)-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol. May play a role in vesicular trafficking through its PAP activity at cortical actin patches.

Below are the list of possible Phosphatidate phosphatase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phosphatidate phosphatase APP1

 Phosphatidate phosphatase APP1 ELISA Kit
 Phosphatidate phosphatase APP1 Recombinant
 Phosphatidate phosphatase APP1 Antibody
Also known as Phosphatidate phosphatase APP1 (PAP) (Actin patch protein 1).
Mg2+-dependent phosphatidate (PA) phosphatase which catalyzes the dephosphorylation of PA to yield diacylglycerol. May play a role in vesicular trafficking through its PAP activity at cortical actin patches.
 APP1 ELISA Kit
 APP1 Recombinant
 APP1 Antibody
 YNL094W ELISA Kit
 YNL094W Recombinant
 YNL094W Antibody
 N2219 ELISA Kit
 N2219 Recombinant
 N2219 Antibody
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Phosphatidate phosphatase LPIN1

 Phosphatidate phosphatase LPIN1 ELISA Kit
 Phosphatidate phosphatase LPIN1 Recombinant
 Phosphatidate phosphatase LPIN1 Antibody
Also known as Phosphatidate phosphatase LPIN1 (Fatty liver dystrophy protein) (Lipin-1).
LPIN1: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthe
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sis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression. Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol. Interacts (via LXXIL motif) with PPARA. Interacts with PPARGC1A. Interaction with PPARA and PPARGC1A leads to the formation of a complex that modulates gene transcription. Interacts with MEF2C. Specifically expressed in skeletal muscle. Also abundant in adipose tissue. Lower levels in some portions of the digestive tract. Inhibited by N-ethylmaleimide. Belongs to the lipin family.

Protein type: EC 3.1.3.4; Phosphatase, lipid

Cellular Component: nucleus; transcription factor complex

Molecular Function: histone deacetylase binding; phosphatidate phosphatase activity; protein binding

Biological Process: actin cytoskeleton reorganization; cellular response to insulin stimulus; lipid metabolic process; negative regulation of transcription from RNA polymerase II promoter; positive regulation of histone deacetylation; positive regulation of transcription from RNA polymerase II promoter; regulation of fat cell differentiation; ruffle organization and biogenesis; triacylglycerol biosynthetic process
 Lpin1 ELISA Kit
 Lpin1 Recombinant
 Lpin1 Antibody
 Fld ELISA Kit
 Fld Recombinant
 Fld Antibody
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Phosphatidate phosphatase LPIN2

 Phosphatidate phosphatase LPIN2 ELISA Kit
 Phosphatidate phosphatase LPIN2 Recombinant
 Phosphatidate phosphatase LPIN2 Antibody
Also known as Phosphatidate phosphatase LPIN2 (Lipin-2).
LPIN2: Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic
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membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism. Defects in LPIN2 are the cause of Majeed syndrome (MAJEEDS). An autosomal recessive syndrome characterized by chronic recurrent multifocal osteomyelitis that is of early onset with a lifelong course, congenital dyserythropoietic anemia that presents as hypochromic, microcytic anemia during the first year of life and ranges from mild to transfusion-dependent, and transient inflammatory dermatosis, often manifesting as Sweet syndrome (neutrophilic skin infiltration). Belongs to the lipin family.

Protein type: EC 3.1.3.4; Phosphatase (non-protein); Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 18p11.31

Cellular Component: cytosol; endoplasmic reticulum membrane; nucleus

Molecular Function: phosphatidate phosphatase activity; transcription coactivator activity

Biological Process: fatty acid catabolic process; lipid metabolic process; phosphatidylcholine biosynthetic process; phosphatidylethanolamine biosynthetic process; positive regulation of transcription from RNA polymerase II promoter; triacylglycerol biosynthetic process

Disease: Majeed Syndrome
 LPIN2 ELISA Kit
 LPIN2 Recombinant
 LPIN2 Antibody
 KIAA0249 ELISA Kit
 KIAA0249 Recombinant
 KIAA0249 Antibody
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Phosphatidate phosphatase LPIN3

 Phosphatidate phosphatase LPIN3 ELISA Kit
 Phosphatidate phosphatase LPIN3 Recombinant
 Phosphatidate phosphatase LPIN3 Antibody
Also known as Phosphatidate phosphatase LPIN3 (Lipin-3).
Regulates fatty acid metabolism. Magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis ().
 Lpin3 ELISA Kit
 Lpin3 Recombinant
 Lpin3 Antibody
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Phosphatidate phosphatase PAH1

 Phosphatidate phosphatase PAH1 ELISA Kit
 Phosphatidate phosphatase PAH1 Recombinant
 Phosphatidate phosphatase PAH1 Antibody
Also known as Phosphatidate phosphatase PAH1 (Phosphatidic acid phosphohydrolase 1) (AtPAH1).
The PAH1 gene encodes a phosphatidate phosphohydrolase. Mutant analysis revealed its involvement in galactolipid synthesis pathway, and the membrane lipid remodeling. The pah1pah2 double-mutant showed enhanced Al-susceptibility under low-P conditions, but there was no significant differences in Al tolerance between pah1pah2 and wild type when they were grown in a solution containing 35 muM Pi.
 PAH1 ELISA Kit
 PAH1 Recombinant
 PAH1 Antibody
 At3g09560 ELISA Kit
 At3g09560 Recombinant
 At3g09560 Antibody
 F11F8.14 ELISA Kit
 F11F8.14 Recombinant
 F11F8.14 Antibody
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Phosphatidate phosphatase PAH2

 Phosphatidate phosphatase PAH2 ELISA Kit
 Phosphatidate phosphatase PAH2 Recombinant
 Phosphatidate phosphatase PAH2 Antibody
Also known as Phosphatidate phosphatase PAH2 (Phosphatidic acid phosphohydrolase 2) (AtPAH2).
Magnesium-dependent phosphatidate phosphatase which catalyzes the dephosphorylation of phosphatidate to yield diacylglycerol. Acts redundantly with PAH1 to repress phospholipid biosynthesis at the endoplasmic reticulum (ER). May function indirectly as repressor of multiple enzymes involved in phospholipid biosynthesis. Is involved in the pathway of galactolipid synthesis in the ER, which is required for the membrane lipid remodeling, an essential adaptation mechanism to cope with phosphate starvati
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on.
 PAH2 ELISA Kit
 PAH2 Recombinant
 PAH2 Antibody
 At5g42870 ELISA Kit
 At5g42870 Recombinant
 At5g42870 Antibody
 MBD2.6 ELISA Kit
 MBD2.6 Recombinant
 MBD2.6 Antibody
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