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Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

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Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase (By similarity).

Below are the list of possible Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein

 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein ELISA Kit
 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Recombinant
 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein Antibody
Also known as Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (P-Rex2) (PtdIns(3,4,5)-dependent Rac exchanger 2) (DEP domain-containing protein 2).
PREX2: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and t
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he beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rac/Rho; Phosphatase, regulatory subunit

Cellular Component: plasma membrane

Molecular Function: GTPase activator activity; Rac guanyl-nucleotide exchange factor activity

Biological Process: adult locomotory behavior; dendrite morphogenesis; G-protein coupled receptor protein signaling pathway; phosphoinositide 3-kinase cascade
 Prex2 ELISA Kit
 Prex2 Recombinant
 Prex2 Antibody
 Depdc2 ELISA Kit
 Depdc2 Recombinant
 Depdc2 Antibody
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