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Phosphatidylinositol 5-phosphate 4-kinase

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Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis and the terminal maturation of megakaryocytes and regulation of their size (By similarity).

Below are the list of possible Phosphatidylinositol 5-phosphate 4-kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha ELISA Kit
 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Recombinant
 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Antibody
Also known as Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha) (Diphosphoinositide kinase 2-alpha) (Phosphatidylinositol 5-phosphate 4-kinase type II alpha) (PI(5)P 4-kinase type II alpha) (PIP4.
Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phospha
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tidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis and the terminal maturation of megakaryocytes and regulation of their size ().
 PIP4K2A ELISA Kit
 PIP4K2A Recombinant
 PIP4K2A Antibody
 PIP5K2A ELISA Kit
 PIP5K2A Recombinant
 PIP5K2A Antibody
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Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta ELISA Kit
 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Recombinant
 Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Antibody
Also known as Phosphatidylinositol 5-phosphate 4-kinase type-2 beta (1-phosphatidylinositol 5-phosphate 4-kinase 2-beta) (Diphosphoinositide kinase 2-beta) (Phosphatidylinositol 5-phosphate 4-kinase type II beta) (PI(5)P 4-kinase type II beta) (PIP4KII-b.
PIP4K2B: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Homodimer. Binds TNFRSF1A. Interacts with PIP4K2A. Intera
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ction with PIP4K2A suppresses ubiquitination by the SPOP/ CUL3 complex. Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.149; Kinase, lipid; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: autophagic vacuole; cytosol; nucleoplasm

Molecular Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity; protein binding; receptor signaling protein activity

Biological Process: cell surface receptor linked signal transduction; phosphatidylinositol biosynthetic process; regulation of autophagy; regulation of phosphoinositide 3-kinase cascade
 PIP4K2B ELISA Kit
 PIP4K2B Recombinant
 PIP4K2B Antibody
 PIP5K2B ELISA Kit
 PIP5K2B Recombinant
 PIP5K2B Antibody
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Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma ELISA Kit
 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Recombinant
 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Antibody
Also known as Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma (Phosphatidylinositol 5-phosphate 4-kinase type II gamma) (PI(5)P 4-kinase type II gamma) (PIP4KII-gamma).
PIP4K2C: May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2), in the endoplasmic reticulum. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: C
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arbohydrate Metabolism - inositol phosphate; EC 2.7.1.149; Endoplasmic reticulum; Kinase, lipid; Motility/polarity/chemotaxis

Cellular Component: autophagic vacuole; endoplasmic reticulum

Molecular Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity; 1-phosphatidylinositol-5-phosphate 4-kinase activity

Biological Process: regulation of autophagy
 Pip4k2c ELISA Kit
 Pip4k2c Recombinant
 Pip4k2c Antibody
 Pip5k2c ELISA Kit
 Pip5k2c Recombinant
 Pip5k2c Antibody
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Proteins Root Name Listing
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