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Phosphofurin acidic cluster sorting protein

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Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the adapter-protein complex-1 (AP-1) of endosomal clathrin-coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN.

Below are the list of possible Phosphofurin acidic cluster sorting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phosphofurin acidic cluster sorting protein 1

 Phosphofurin acidic cluster sorting protein 1 ELISA Kit
 Phosphofurin acidic cluster sorting protein 1 Recombinant
 Phosphofurin acidic cluster sorting protein 1 Antibody
Also known as Phosphofurin acidic cluster sorting protein 1 (PACS-1).
PACS-1: Coat protein that is involved in the localization of trans-Golgi network (TGN) membrane proteins that contain acidic cluster sorting motifs. Controls the endosome-to-Golgi trafficking of furin and mannose-6-phosphate receptor by connecting the acidic-cluster-containing cytoplasmic domain of these molecules with the ad
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apter-protein complex-1 (AP-1) of endosomal clathrin- coated membrane pits. Involved in HIV-1 nef-mediated removal of MHC-I from the cell surface to the TGN. Belongs to the PACS family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 11q13.1-q13.2

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: regulation of defense response to virus by virus

Disease: Mental Retardation, Autosomal Dominant 17
 PACS1 ELISA Kit
 PACS1 Recombinant
 PACS1 Antibody
 KIAA1175 ELISA Kit
 KIAA1175 Recombinant
 KIAA1175 Antibody
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Phosphofurin acidic cluster sorting protein 2

 Phosphofurin acidic cluster sorting protein 2 ELISA Kit
 Phosphofurin acidic cluster sorting protein 2 Recombinant
 Phosphofurin acidic cluster sorting protein 2 Antibody
Also known as Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein).
PACS2: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidi
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c cluster-containing ion channels to distinct subcellular compartments. Belongs to the PACS family. 3 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cell; endoplasmic reticulum; intracellular

Biological Process: autophagic vacuole formation
 Pacs2 ELISA Kit
 Pacs2 Recombinant
 Pacs2 Antibody
 Kiaa0602 ELISA Kit
 Kiaa0602 Recombinant
 Kiaa0602 Antibody
 Pacs1l ELISA Kit
 Pacs1l Recombinant
 Pacs1l Antibody
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