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Phospholipase A2 crotoxin

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Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission .

Below are the list of possible Phospholipase A2 crotoxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phospholipase A2 crotoxin basic chain

 Phospholipase A2 crotoxin basic chain ELISA Kit
 Phospholipase A2 crotoxin basic chain Recombinant
 Phospholipase A2 crotoxin basic chain Antibody
Also known as Phospholipase A2 crotoxin basic chain (CB) (Crotoxin-B) (svPLA2) (CdcolF6a) (F6a) (Phosphatidylcholine 2-acylhydrolase).
Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin
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that possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission (PubMed:17203389, PubMed:16003952). It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CB), with a small acidic, non-enzymatic and non-toxic subunit (CA also named crotapotin). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert nephrotoxicity, and cardiovascular toxicity. Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported ().
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Phospholipase A2 crotoxin basic chain 3

 Phospholipase A2 crotoxin basic chain 3 ELISA Kit
 Phospholipase A2 crotoxin basic chain 3 Recombinant
 Phospholipase A2 crotoxin basic chain 3 Antibody
Also known as Phospholipase A2 crotoxin basic chain 3 (CB3) (svPLA2) (Phosphatidylcholine 2-acylhydrolase).
Snake venom phospholipase A2 (PLA2) that shows presynaptic neurotoxicity. PLA2 catalyzes
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the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
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Phospholipase A2 crotoxin basic chain CBa2

 Phospholipase A2 crotoxin basic chain CBa2 ELISA Kit
 Phospholipase A2 crotoxin basic chain CBa2 Recombinant
 Phospholipase A2 crotoxin basic chain CBa2 Antibody
Also known as Phospholipase A2 crotoxin basic chain CBa2 (CB2) (CTX subunit CBa2) (svPLA2) (Phosphatidylcholine 2-acylhydrolase).
Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that
>>>
possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity (PubMed:20109480). Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported (PubMed:20109480).
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Phospholipase A2 crotoxin basic subunit CBb

 Phospholipase A2 crotoxin basic subunit CBb ELISA Kit
 Phospholipase A2 crotoxin basic subunit CBb Recombinant
 Phospholipase A2 crotoxin basic subunit CBb Antibody
Also known as Phospholipase A2 crotoxin basic subunit CBb (CTX subunit CBb) (svPLA2) (Phosphatidylcholine 2-acylhydrolase).
Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that posse
>>>
sses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity (PubMed:20109480). Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported (PubMed:20109480).
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Phospholipase A2 crotoxin basic subunit CBc

 Phospholipase A2 crotoxin basic subunit CBc ELISA Kit
 Phospholipase A2 crotoxin basic subunit CBc Recombinant
 Phospholipase A2 crotoxin basic subunit CBc Antibody
Also known as Phospholipase A2 crotoxin basic subunit CBc (CB1) (CTX subunit CBc) (svPLA2) (Phosphatidylcholine 2-acylhydrolase).
Heterodimer CA-CB: Crotoxin is a potent presynaptic neurotoxin that
>>>
possesses phospholipase A2 (PLA2) activity and exerts a lethal action by blocking neuromuscular transmission. It consists of a non-covalent association of a basic and weakly toxic PLA2 subunit (CBa2, CBb, CBc, or CBd), with a small acidic, non-enzymatic and non-toxic subunit (CA1, CA2, CA3 or CA4). The complex acts by binding to a specific 48-kDa protein (R48) receptor located on presynaptic membranes, forming a transient ternary complex CA-CB-R48, followed by dissociation of the CA-CB complex and release of the CA subunit. At equilibrium, only the CB subunits remain associated with the specific crotoxin receptor. In addition to neurotoxicity, crotoxin has been found to exert myotoxicity, nephrotoxicity, and cardiovascular toxicity (PubMed:20109480). Moreover, anti-inflammatory, immunomodulatory, anti-tumor and analgesic effects of crotoxin have also been reported (PubMed:20109480).
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