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Phospholipid phosphatase

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Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), diacyl glycerol pyrophosphate (DGPP), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > C-1-P > S-1-P.

Below are the list of possible Phospholipid phosphatase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phospholipid phosphatase 1

 Phospholipid phosphatase 1 ELISA Kit
 Phospholipid phosphatase 1 Recombinant
 Phospholipid phosphatase 1 Antibody
Also known as Phospholipid phosphatase 1 (35 kDa PAP) (mPAP) (Hydrogen peroxide-inducible protein 53) (Hic53) (Lipid phosphate phosphohydrolase 1) (PAP2-alpha) (Phosphatidate phosphohydrolase type 2a) (Phosphatidic acid phosphatase 2a) (PAP-2a) (PAP2a).
PPAP2A: Broad-specificity phosphohydrolase that dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system. Major enzyme responsible of dephosphorylating LPA in platelet
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s, which terminates signaling actions of LPA. May control circulating, and possibly also regulate localized, LPA levels resulting from platelet activation. It has little activity towards ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA > PA > S-1-P > C-1-P. It's down-regulation may contribute to the development of colon adenocarcinoma. Belongs to the PA-phosphatase related phosphoesterase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.4; Lipid Metabolism - ether lipid; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; Lipid Metabolism - sphingolipid; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Phosphatase (non-protein)

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: lipid phosphatase activity; phosphatidate phosphatase activity

Biological Process: ceramide metabolic process; diacylglycerol biosynthetic process; phospholipid dephosphorylation; phospholipid metabolic process; protein amino acid dephosphorylation; signal transduction; sphingosine metabolic process
 Plpp1 ELISA Kit
 Plpp1 Recombinant
 Plpp1 Antibody
 Hpic53 ELISA Kit
 Hpic53 Recombinant
 Hpic53 Antibody
 Lpp1 ELISA Kit
 Lpp1 Recombinant
 Lpp1 Antibody
 Ppap2a ELISA Kit
 Ppap2a Recombinant
 Ppap2a Antibody
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Phospholipid phosphatase 2

 Phospholipid phosphatase 2 ELISA Kit
 Phospholipid phosphatase 2 Recombinant
 Phospholipid phosphatase 2 Antibody
Also known as Phospholipid phosphatase 2 (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c).
catalyzes the conversion of phosphatidic acid to diacylglycerol and inorganic phosphate [RGD, Feb 2006]
 Plpp2 ELISA Kit
 Plpp2 Recombinant
 Plpp2 Antibody
 Lpp2 ELISA Kit
 Lpp2 Recombinant
 Lpp2 Antibody
 Ppap2c ELISA Kit
 Ppap2c Recombinant
 Ppap2c Antibody
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Phospholipid phosphatase 3

 Phospholipid phosphatase 3 ELISA Kit
 Phospholipid phosphatase 3 Recombinant
 Phospholipid phosphatase 3 Antibody
Also known as Phospholipid phosphatase 3 (Differentially expressed in rat intestine 42) (Dri42) (Lipid phosphate phosphohydrolase 3) (PAP2-beta) (Phosphatidate phosphohydrolase type 2b) (Phosphatidic acid phosphatase 2b) (PAP-2b) (PAP2b).
an endoplasmic reticulum resident protein; upregulated during epithelial differentiation [RGD, Feb 2006]
 Plpp3 ELISA Kit
 Plpp3 Recombinant
 Plpp3 Antibody
 Lpp3 ELISA Kit
 Lpp3 Recombinant
 Lpp3 Antibody
 Ppap2b ELISA Kit
 Ppap2b Recombinant
 Ppap2b Antibody
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Phospholipid phosphatase 4

 Phospholipid phosphatase 4 ELISA Kit
 Phospholipid phosphatase 4 Recombinant
 Phospholipid phosphatase 4 Antibody
Also known as Phospholipid phosphatase 4 (Phosphatidic acid phosphatase type 2 domain-containing protein 1A).
PPAPDC1A: Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. Belongs to the PA-phosphatase related phosphoesterase family. 4 isoforms of the human protein are produced by alternative splicing.
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br>Protein type: EC 3.1.3.4; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: integral to plasma membrane

Molecular Function: phosphatidate phosphatase activity

Biological Process: phospholipid dephosphorylation; phospholipid metabolic process; signal transduction
 Plpp4 ELISA Kit
 Plpp4 Recombinant
 Plpp4 Antibody
 Ppapdc1a ELISA Kit
 Ppapdc1a Recombinant
 Ppapdc1a Antibody
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Phospholipid phosphatase 5

 Phospholipid phosphatase 5 ELISA Kit
 Phospholipid phosphatase 5 Recombinant
 Phospholipid phosphatase 5 Antibody
Also known as Phospholipid phosphatase 5 (Phosphatidic acid phosphatase type 2 domain-containing protein 1B).
PPAPDC1B: Displays magnesium-independent phosphatidate phosphatase activity in vitro. Catalyzes the conversion of phosphatidic acid to diacylglycerol. May be a metastatic suppressor for hepatocellular carcinoma. Belongs to the PA-phosphatase related phosphoesterase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.3.4; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Tumor suppressor

Cellular Componen
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t: integral to plasma membrane

Molecular Function: phosphatidate phosphatase activity

Biological Process: phospholipid dephosphorylation; phospholipid metabolic process; signal transduction
 Plpp5 ELISA Kit
 Plpp5 Recombinant
 Plpp5 Antibody
 Ppapdc1 ELISA Kit
 Ppapdc1 Recombinant
 Ppapdc1 Antibody
 Ppapdc1b ELISA Kit
 Ppapdc1b Recombinant
 Ppapdc1b Antibody
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Phospholipid phosphatase 6

 Phospholipid phosphatase 6 ELISA Kit
 Phospholipid phosphatase 6 Recombinant
 Phospholipid phosphatase 6 Antibody
Also known as Phospholipid phosphatase 6 (Phosphatidic acid phosphatase type 2 domain-containing protein 2) (PPAP2 domain-containing protein 2) (Presqualene diphosphate phosphatase).
PPAPDC2: Phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapi
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dly remodels to presqualene monophosphate PSMP upon cell activation. Displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. Belongs to the PA-phosphatase related phosphoesterase family.

Protein type: EC 3.1.3.-; Membrane protein, integral; Membrane protein, multi-pass; Phosphatase

Chromosomal Location of Human Ortholog: 9p24.1
 PLPP6 ELISA Kit
 PLPP6 Recombinant
 PLPP6 Antibody
 PPAPDC2 ELISA Kit
 PPAPDC2 Recombinant
 PPAPDC2 Antibody
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