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Phosphoprotein associated with glycosphingolipid-enriched microdomains

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Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Below are the list of possible Phosphoprotein associated with glycosphingolipid-enriched microdomains products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 ELISA Kit
 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Recombinant
 Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 Antibody
Also known as Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane adapter protein PAG) (Transmembrane phosphoprotein Cbp).
PAG: an ubiquitous type III transmembrane adaptor protein that binds to the tyrosine kinase CSK protein. It is thought to be involved in the regulation of T cell activation.

Protein type: Adaptor/scaffold; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q21.13

Cellular Component: integral to plasma membrane; lipid raft; plasma membrane

Molecular Function: protein bi
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nding; SH2 domain binding; transmembrane receptor protein tyrosine kinase adaptor protein activity

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of T cell activation; regulation of T cell activation; signal transduction; T cell receptor signaling pathway; transmembrane receptor protein tyrosine kinase signaling pathway
 PAG1 ELISA Kit
 PAG1 Recombinant
 PAG1 Antibody
 CBP ELISA Kit
 CBP Recombinant
 CBP Antibody
 PAG ELISA Kit
 PAG Recombinant
 PAG Antibody
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