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Pigment epithelium-derived factor

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Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Below are the list of possible Pigment epithelium-derived factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pigment epithelium-derived factor

 Pigment epithelium-derived factor ELISA Kit
 Pigment epithelium-derived factor Recombinant
 Pigment epithelium-derived factor Antibody
Also known as Pigment epithelium-derived factor (PEDF) (Caspin) (Serpin F1) (Stromal cell-derived factor 3) (SDF-3).
PEDF: a secreted neurotrophic protein that induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The N-terminal (AA 44-121) exhibits neurite outgrowth-inducing activity. The C-terminal exposed loop (AA 382-418) is essential for serpin activity. Extracellular phosph
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orylation enhances antiangiogenic activity.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Cellular Component: axon; axon hillock; basement membrane; cell soma; extracellular matrix; extracellular region; extracellular space; perinuclear region of cytoplasm

Molecular Function: serine-type endopeptidase inhibitor activity

Biological Process: negative regulation of angiogenesis; negative regulation of inflammatory response; positive regulation of neurogenesis; short-term memory
 Serpinf1 ELISA Kit
 Serpinf1 Recombinant
 Serpinf1 Antibody
 Pedf ELISA Kit
 Pedf Recombinant
 Pedf Antibody
 Sdf3 ELISA Kit
 Sdf3 Recombinant
 Sdf3 Antibody
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