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Transcriptional coregulator of NF-kappa-B which facilitates binding of NF-kappa-B proteins to target kappa-B genes in a redox-state-dependent manner. May be required for efficient terminal myeloid maturation of hematopoietic cells. Has quercetin 2,3-dioxygenase activity (in vitro).

Below are the list of possible Pirin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.


 Pirin ELISA Kit
 Pirin Recombinant
 Pirin Antibody
Also known as Pirin (Probable quercetin 2,3-dioxygenase PIR) (Probable quercetinase).
PIR: Possible transcriptional coregulator. May contribute to the regulation of cellular processes via its interaction with BCL3. May be required for efficient terminal myeloid maturation of hematopoietic cells. May play a role in the regulation of cell migration. May promote apoptosis when overexpressed. Has q
uercetin 2,3-dioxygenase activity (in vitro). May interact with NF1/CTF1. Interacts with BCL3. Identified in a complex comprised of PIR, BLC3, NFKB1 and target DNA. Up-regulated in CD34(+) cells upon myelomonocytic differentiation. Down-regulated in many acute myeloid leukemias. Up-regulated in primary bronchial epithelial cells exposed to cigarette smoke extract. Highly expressed in a subset of melanomas. Detected at very low levels in most tissues. Expressed in all tissues, with highest level of expression in heart and liver. Inhibited by kojic acid, sodium diethyldithiocarbamate and 1,10-phenanthroline monohydrochloride. Belongs to the pirin family.

Protein type: EC; Oxidoreductase; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: Xp22.2

Cellular Component: cytoplasm; nucleus

Molecular Function: metal ion binding; protein binding; quercetin 2,3-dioxygenase activity; transcription cofactor activity

Biological Process: monocyte differentiation; transcription from RNA polymerase II promoter
 PIR Recombinant
 PIR Antibody
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 Pirin-1 ELISA Kit
 Pirin-1 Recombinant
 Pirin-1 Antibody
Also known as Pirin-1 (AtPirin1).
encodes a cupin-domain containing protein that is similar to pirins which interact with a CCAAT box binding transcription factor. The protein interacts with GPA1 (G protein alpha-subunit) in vitro. Mutants in the gene are affected in germination and early seedling development.
 PRN1 Recombinant
 PRN1 Antibody
 At3g59220 ELISA Kit
 At3g59220 Recombinant
 At3g59220 Antibody
 F25L23_80 ELISA Kit
 F25L23_80 Recombinant
 F25L23_80 Antibody
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