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Pituitary-specific positive transcription factor

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Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes .

Below are the list of possible Pituitary-specific positive transcription factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pituitary-specific positive transcription factor 1

 Pituitary-specific positive transcription factor 1 ELISA Kit
 Pituitary-specific positive transcription factor 1 Recombinant
 Pituitary-specific positive transcription factor 1 Antibody
Also known as Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1).
GHF-1: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'- TAAAT-3'. Belongs to the POU transcription factor family. Class- 1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human
>>>
Ortholog: 3p11

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription from RNA polymerase II promoter

Disease: Pituitary Hormone Deficiency, Combined, 1
 POU1F1 ELISA Kit
 POU1F1 Recombinant
 POU1F1 Antibody
 GHF1 ELISA Kit
 GHF1 Recombinant
 GHF1 Antibody
 PIT1 ELISA Kit
 PIT1 Recombinant
 PIT1 Antibody
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