Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Platelet endothelial cell adhesion molecule  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • CEP290 Antibody
 • RASL10A Antibody
 • GPR114 Antibody
 • Titin Antibody (TTN) ELISA Kit
 • Arachidonate 5-Lipoxygenase (ALOX-5) ELISA Kit
 • Saccharomyces Cerevisiae Antibody (SCA) ELISA Kit
 • Interleukin 4 (IL4) ELISA Kit
 • Soluble CD44V9 (SCD44V9) ELISA Kit
 • Tolloid Like Protein 1 (TLL1) ELISA Kit
 • Aconitase 2 (ACO-2) ELISA Kit
 • Carboxymethyl Lysine (CML) ELISA Kit
 • Map Kinase Phosphatase 1 (MKP-1) ELISA Kit
 • Cyclic Amp Response Element Binding Protein (CREB) ELISA Kit
 • A1-Microglobulin (A1-MG) ELISA Kit
 downarrow more ...
separator

Platelet endothelial cell adhesion molecule

separator
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-660 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Modulates BDKRB2 activation. Induces susceptibility to atherosclerosis (By similarity).

Below are the list of possible Platelet endothelial cell adhesion molecule products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Platelet endothelial cell adhesion molecule

 Platelet endothelial cell adhesion molecule ELISA Kit
 Platelet endothelial cell adhesion molecule Recombinant
 Platelet endothelial cell adhesion molecule Antibody
Also known as Platelet endothelial cell adhesion molecule (PECAM-1) (CD antigen CD31).
PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage p
>>>
hagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis

Cellular Component: cell surface; external side of plasma membrane; extracellular space; lipid raft; membrane; plasma membrane; ruffle; smooth muscle contractile fiber

Molecular Function: protein phosphatase binding

Biological Process: angiogenesis; diapedesis; endothelial cell migration; endothelial cell morphogenesis; negative regulation of actin filament polymerization; negative regulation of peptidyl-tyrosine phosphorylation; phagocytosis; positive regulation of cellular extravasation; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of Stat5 protein; regulation of cell migration; Rho protein signal transduction; wound healing
 Pecam1 ELISA Kit
 Pecam1 Recombinant
 Pecam1 Antibody
 Pecam ELISA Kit
 Pecam Recombinant
 Pecam Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions