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Pleckstrin homology-like domain family

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Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.

Below are the list of possible Pleckstrin homology-like domain family products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pleckstrin homology-like domain family A member 1

 Pleckstrin homology-like domain family A member 1 ELISA Kit
 Pleckstrin homology-like domain family A member 1 Recombinant
 Pleckstrin homology-like domain family A member 1 Antibody
Also known as Pleckstrin homology-like domain family A member 1 (Apoptosis-associated nuclear protein) (Proline- and glutamine-rich protein) (PQ-rich protein) (PQR protein) (Proline- and histidine-rich protein) (T-cell death-associated gene 51 protein).
PHLDA1: Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.

Protein type: Apoptosis; Nucleolus

Chromosomal Lo
>>>
cation of Human Ortholog: 12q15

Cellular Component: cytosol

Molecular Function: protein binding

Biological Process: G2/M transition of mitotic cell cycle
 PHLDA1 ELISA Kit
 PHLDA1 Recombinant
 PHLDA1 Antibody
 PHRIP ELISA Kit
 PHRIP Recombinant
 PHRIP Antibody
 TDAG51 ELISA Kit
 TDAG51 Recombinant
 TDAG51 Antibody
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Pleckstrin homology-like domain family A member 2

 Pleckstrin homology-like domain family A member 2 ELISA Kit
 Pleckstrin homology-like domain family A member 2 Recombinant
 Pleckstrin homology-like domain family A member 2 Antibody
Also known as Pleckstrin homology-like domain family A member 2 (Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein) (Imprinted in placenta and liver protein) (Tumor-suppressing STF cDNA 3 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein) (p17-Beckwith-Wiedemann region 1 C) (p17-BWR1C).
PHLDA2: a protein may play a role in regulating placenta growth. Contains one PH domain. Expressed in placenta and adult prostate gland. Expressed at low levels in adult liver and lung, and fetal liver. Expressed in adult brain and neuroblastoma
>>>
, medullablastoma and glioblastoma cell lines.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11p15.4

Biological Process: apoptosis
 PHLDA2 ELISA Kit
 PHLDA2 Recombinant
 PHLDA2 Antibody
 BWR1C ELISA Kit
 BWR1C Recombinant
 BWR1C Antibody
 HLDA2 ELISA Kit
 HLDA2 Recombinant
 HLDA2 Antibody
 IPL ELISA Kit
 IPL Recombinant
 IPL Antibody
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Pleckstrin homology-like domain family A member 3

 Pleckstrin homology-like domain family A member 3 ELISA Kit
 Pleckstrin homology-like domain family A member 3 Recombinant
 Pleckstrin homology-like domain family A member 3 Antibody
Also known as Pleckstrin homology-like domain family A member 3 (TDAG51/Ipl homolog 1).
PHLDA3: p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulatio
>>>
n by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor. Belongs to the PHLDA3 family. Induced by p53/TP53; expression is directly activated by p53/TP53. p53/TP53 phosphorylation on 'Ser-15' is required to activate the PHLDA3 promoter.

Protein type: Tumor suppressor

Cellular Component: plasma membrane

Molecular Function: phosphatidylinositol 3-phosphate binding; phosphatidylinositol-3,4,5-triphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-5-phosphate binding

Biological Process: DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; negative regulation of protein kinase B signaling cascade; positive regulation of apoptosis
 Phlda3 ELISA Kit
 Phlda3 Recombinant
 Phlda3 Antibody
 Tih1 ELISA Kit
 Tih1 Recombinant
 Tih1 Antibody
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Pleckstrin homology-like domain family B member 1

 Pleckstrin homology-like domain family B member 1 ELISA Kit
 Pleckstrin homology-like domain family B member 1 Recombinant
 Pleckstrin homology-like domain family B member 1 Antibody
Also known as Pleckstrin homology-like domain family B member 1 (Protein LL5-alpha).
PHLDB1: 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Cellular Component: basal cortex

Biological Process: regulation of gastrulation
 Phldb1 ELISA Kit
 Phldb1 Recombinant
 Phldb1 Antibody
 Ll5 ELISA Kit
 Ll5 Recombinant
 Ll5 Antibody
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Pleckstrin homology-like domain family B member 2

 Pleckstrin homology-like domain family B member 2 ELISA Kit
 Pleckstrin homology-like domain family B member 2 Recombinant
 Pleckstrin homology-like domain family B member 2 Antibody
Also known as Pleckstrin homology-like domain family B member 2 (Protein LL5-beta).
PHLDB2: Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Cellular Component: basal cortex; cell-
>>>
cell adherens junction; cytoplasm; focal adhesion; intermediate filament cytoskeleton; leading edge; plasma membrane

Biological Process: establishment of protein localization; microtubule cytoskeleton organization and biogenesis; negative regulation of focal adhesion formation; negative regulation of stress fiber formation; regulation of gastrulation
 Phldb2 ELISA Kit
 Phldb2 Recombinant
 Phldb2 Antibody
 Ll5b ELISA Kit
 Ll5b Recombinant
 Ll5b Antibody
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Pleckstrin homology-like domain family B member 3

 Pleckstrin homology-like domain family B member 3 ELISA Kit
 Pleckstrin homology-like domain family B member 3 Recombinant
 Pleckstrin homology-like domain family B member 3 Antibody
PHLDB3: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.31

Molecular Function: enzyme binding
 PHLDB3 ELISA Kit
 PHLDB3 Recombinant
 PHLDB3 Antibody
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