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Podoplanin

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May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.

Below are the list of possible Podoplanin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Podoplanin

 Podoplanin ELISA Kit
 Podoplanin Recombinant
 Podoplanin Antibody
Also known as Podoplanin (Aggrus) (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1-alpha) (T1A).
PDPN: May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does n
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ot function as a water channel or as a regulator of aquaporin-type water channels. Belongs to the podoplanin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.21

Cellular Component: filopodium; integral to plasma membrane; lamellipodium; plasma membrane; ruffle

Molecular Function: amino acid transmembrane transporter activity; folic acid transporter activity; water channel activity; water transporter activity

Biological Process: amino acid transport; cell morphogenesis; cell motility involved in cell locomotion; folic acid transport; lung development; lymphangiogenesis; platelet activation; positive regulation of cell motility; water transport
 PDPN ELISA Kit
 PDPN Recombinant
 PDPN Antibody
 GP36 ELISA Kit
 GP36 Recombinant
 GP36 Antibody
 PSEC0003 ELISA Kit
 PSEC0003 Recombinant
 PSEC0003 Antibody
 PSEC0025 ELISA Kit
 PSEC0025 Recombinant
 PSEC0025 Antibody
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