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Poly(ADP-ribose) glycohydrolase

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Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP-ribose monomers. Required for retinoid acid-dependent gene transactivation, probably by dePARsylating histone demethylase KDM4D, allowing chromatin derepression at RAR-dependent gene promoters. Involved in the synthesis of ATP in the nucleus, together with PARP1, NMNAT1 and NUDT5. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.

Below are the list of possible Poly(ADP-ribose) glycohydrolase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Poly(ADP-ribose) glycohydrolase

 Poly(ADP-ribose) glycohydrolase ELISA Kit
 Poly(ADP-ribose) glycohydrolase Recombinant
 Poly(ADP-ribose) glycohydrolase Antibody
PARG: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Belongs to the poly(ADP-ribose) glycohydrolase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.2.1.143
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; Hydrolase

Cellular Component: chromatin; cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm; nucleus

Molecular Function: chromatin binding; poly(ADP-ribose) glycohydrolase activity

Biological Process: detection of bacterium; positive regulation of DNA repair; response to DNA damage stimulus
 Parg ELISA Kit
 Parg Recombinant
 Parg Antibody
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Poly(ADP-ribose) glycohydrolase 1

 Poly(ADP-ribose) glycohydrolase 1 ELISA Kit
 Poly(ADP-ribose) glycohydrolase 1 Recombinant
 Poly(ADP-ribose) glycohydrolase 1 Antibody
The gene encodes a poly(ADPribose) glycohydrolase (PARG1). Mutant analysis revealed that PARG1 PARG1 plays a role in abiotic stress responses.
 PARG1 ELISA Kit
 PARG1 Recombinant
 PARG1 Antibody
 TEJ ELISA Kit
 TEJ Recombinant
 TEJ Antibody
 At2g31870 ELISA Kit
 At2g31870 Recombinant
 At2g31870 Antibody
 At2g31875 ELISA Kit
 At2g31875 Recombinant
 At2g31875 Antibody
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Poly(ADP-ribose) glycohydrolase 2

 Poly(ADP-ribose) glycohydrolase 2 ELISA Kit
 Poly(ADP-ribose) glycohydrolase 2 Recombinant
 Poly(ADP-ribose) glycohydrolase 2 Antibody
Also known as Poly(ADP-ribose) glycohydrolase 2 (Poly ADP-ribose metabolism enzyme 4).
Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:17188026). Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells ().
 parg-2 ELISA Kit
 parg-2 Recombinant
 parg-2 Antibody
 pme-4 ELISA Kit
 pme-4 Recombinant
 pme-4 Antibody
 H23L24.5 ELISA Kit
 H23L24.5 Recombinant
 H23L24.5 Antibody
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Poly(ADP-ribose) glycohydrolase ARH3

 Poly(ADP-ribose) glycohydrolase ARH3 ELISA Kit
 Poly(ADP-ribose) glycohydrolase ARH3 Recombinant
 Poly(ADP-ribose) glycohydrolase ARH3 Antibody
Also known as Poly(ADP-ribose) glycohydrolase ARH3 (ADP-ribosylhydrolase 3) ([Protein ADP-ribosylarginine] hydrolase-like protein 2).
ADPRHL2: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase. Poly(ADP-ribose) metabolism may be required for maintenance of the normal function of neuronal cells. Generates ADP-ribo
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se from poly-(ADP-ribose), but does not hydrolyze ADP- ribose-arginine, -cysteine, -diphthamide, or -asparagine bonds. Belongs to the ADP-ribosylglycohydrolase family.

Protein type: EC 3.2.1.143; Hydrolase

Chromosomal Location of Human Ortholog: 1p34.3

Cellular Component: nucleoplasm
 ADPRHL2 ELISA Kit
 ADPRHL2 Recombinant
 ADPRHL2 Antibody
 ARH3 ELISA Kit
 ARH3 Recombinant
 ARH3 Antibody
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