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Polycystic kidney disease 2-like 1 protein

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Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect. May play a role in the perception of carbonation taste.

Below are the list of possible Polycystic kidney disease 2-like 1 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Polycystic kidney disease 2-like 1 protein

 Polycystic kidney disease 2-like 1 protein ELISA Kit
 Polycystic kidney disease 2-like 1 protein Recombinant
 Polycystic kidney disease 2-like 1 protein Antibody
Also known as Polycystic kidney disease 2-like 1 protein (Polycystin-2 homolog).
PKD2L1: May function as a subunit of an ion channel and act as a transducer of calcium-mediated signaling. Belongs to the polycystin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass; Motility/
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polarity/chemotaxis

Cellular Component: cell surface; endoplasmic reticulum; intracellular membrane-bound organelle; membrane; plasma membrane; receptor complex

Molecular Function: alpha-actinin binding; calcium activated cation channel activity; calcium channel activity; calcium ion binding; calcium-activated potassium channel activity; cation channel activity; cation transmembrane transporter activity; cytoskeletal protein binding; identical protein binding; muscle alpha-actinin binding; protein binding; sodium channel activity; sour taste receptor activity

Biological Process: cation transport; detection of chemical stimulus involved in sensory perception of sour taste; detection of mechanical stimulus; sensory perception of sour taste; smoothened signaling pathway
 Pkd2l1 ELISA Kit
 Pkd2l1 Recombinant
 Pkd2l1 Antibody
 Trpp3 ELISA Kit
 Trpp3 Recombinant
 Trpp3 Antibody
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