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Polycystic kidney disease protein

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Component of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD2L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. Does not constitute the pore-forming subunit. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.

Below are the list of possible Polycystic kidney disease protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Polycystic kidney disease protein 1-like 1

 Polycystic kidney disease protein 1-like 1 ELISA Kit
 Polycystic kidney disease protein 1-like 1 Recombinant
 Polycystic kidney disease protein 1-like 1 Antibody
Also known as Polycystic kidney disease protein 1-like 1 (PC1-like 1 protein) (Polycystin-1L1).
PKD1L1: May have a role in the heart and in the male reproductive system. Belongs to the polycystin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of
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Human Ortholog: 7p12.3

Cellular Component: cilium; membrane

Molecular Function: calcium channel activity; protein binding

Biological Process: detection of mechanical stimulus

Disease: Heterotaxy, Visceral, 8, Autosomal
 PKD1L1 ELISA Kit
 PKD1L1 Recombinant
 PKD1L1 Antibody
 UNQ5785/PRO19563 ELISA Kit
 UNQ5785/PRO19563 Recombinant
 UNQ5785/PRO19563 Antibody
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Polycystic kidney disease protein 1-like 2

 Polycystic kidney disease protein 1-like 2 ELISA Kit
 Polycystic kidney disease protein 1-like 2 Recombinant
 Polycystic kidney disease protein 1-like 2 Antibody
Also known as Polycystic kidney disease protein 1-like 2 (PC1-like 2 protein) (Polycystin-1L2).
PKD1L2: May function as an ion-channel regulator. May function as a G-protein-coupled receptor. Belongs to the polycystin family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Cellular Compone
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nt: membrane

Molecular Function: calcium channel activity; G-protein alpha-subunit binding

Biological Process: detection of mechanical stimulus
 Pkd1l2 ELISA Kit
 Pkd1l2 Recombinant
 Pkd1l2 Antibody
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Polycystic kidney disease protein 1-like 3

 Polycystic kidney disease protein 1-like 3 ELISA Kit
 Polycystic kidney disease protein 1-like 3 Recombinant
 Polycystic kidney disease protein 1-like 3 Antibody
Also known as Polycystic kidney disease protein 1-like 3 (PC1-like 3 protein) (Polycystin-1L3).
PKD1L3: May function as an ion-channel regulator. May function with PKD2L1 as heteromeric taste channels. Belongs to the polycystin family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 16q22.2

Cellular Component: c
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ell surface; plasma membrane; receptor complex

Molecular Function: calcium channel activity; cation channel activity; cation transmembrane transporter activity; protein binding; sour taste receptor activity

Biological Process: cation transport; detection of chemical stimulus involved in sensory perception of sour taste; detection of mechanical stimulus; sensory perception of sour taste
 PKD1L3 ELISA Kit
 PKD1L3 Recombinant
 PKD1L3 Antibody
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