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Potassium channel toxin

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Potassium channel toxin AaTXK-beta: blocks voltage-gated potassium channels (Kv) (By similarity). Does not activate Kv7 channels.

Below are the list of possible Potassium channel toxin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Potassium channel toxin AaTXK-beta

 Potassium channel toxin AaTXK-beta ELISA Kit
 Potassium channel toxin AaTXK-beta Recombinant
 Potassium channel toxin AaTXK-beta Antibody
Also known as Potassium channel toxin AaTXK-beta (Toxin AaTXKbeta) (Potassium channel toxin AaTXK-beta(1-64)) (Potassium channel toxin beta-KTx 2).
Potassium channel toxin AaTXK-beta: blocks voltag
>>>
e-gated potassium channels (Kv) (). Does not activate Kv7 channels.
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Potassium channel toxin alpha-KTx

 Potassium channel toxin alpha-KTx ELISA Kit
 Potassium channel toxin alpha-KTx Recombinant
 Potassium channel toxin alpha-KTx Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 1.1

 Potassium channel toxin alpha-KTx 1.1 ELISA Kit
 Potassium channel toxin alpha-KTx 1.1 Recombinant
 Potassium channel toxin alpha-KTx 1.1 Antibody
Also known as Potassium channel toxin alpha-KTx 1.1 (ChTX-Lq1) (ChTx-a) (Charybdotoxin) (CTX) (ChTX).
Potent selective inhibitor of high conductance (maxi-K), different medium and small conductance
>>>
calcium-activated potassium channels (KCa1.1/KCNMA1 and others), as well as a voltage-dependent potassium channel (Kv1.3/KCNA3>Kv1.2/KCNA2>Kv1.6/KCNA3>>Shaker/Sh) (PubMed:2477548, PubMed:8204618, PubMed:7517498, PubMed:20007782). It blocks channel activity by a simple bimolecular inhibition process.
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Potassium channel toxin alpha-KTx 1.10

 Potassium channel toxin alpha-KTx 1.10 ELISA Kit
 Potassium channel toxin alpha-KTx 1.10 Recombinant
 Potassium channel toxin alpha-KTx 1.10 Antibody
Also known as Potassium channel toxin alpha-KTx 1.10 (Parabutoxin-3) (PBTx3).
Reversibly blocks voltage-gated potassium channels (Kv1.1/KCNA1 (Kd=79 µM), Kv1.2/KCNA2 (Kd=547 nM) and Kv1.3/KCNA3 (K
>>>
d=492 nM)).
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Potassium channel toxin alpha-KTx 1.11

 Potassium channel toxin alpha-KTx 1.11 ELISA Kit
 Potassium channel toxin alpha-KTx 1.11 Recombinant
 Potassium channel toxin alpha-KTx 1.11 Antibody
Also known as Potassium channel toxin alpha-KTx 1.11 (Slotoxin) (SloTx).
Reversibly blocks the high conductance calcium-activated potassium channels composed of only alpha subunits (KCa1.1/KCNMA1).
>>>
Unreversibly blocks the high conductance calcium-activated potassium channels composed of alpha and beta1 subunits (KCNMA1 and KCNMB1). Unreversibly and weakly blocks the high conductance calcium-activated potassium channels composed of alpha and beta4 (KCNMA1 and KCNMB4).
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Potassium channel toxin alpha-KTx 1.12

 Potassium channel toxin alpha-KTx 1.12 ELISA Kit
 Potassium channel toxin alpha-KTx 1.12 Recombinant
 Potassium channel toxin alpha-KTx 1.12 Antibody
Also known as Potassium channel toxin alpha-KTx 1.12 (Charybdotoxin b) (ChTx-b).
Potent selective inhibitor of high conductance (maxi-K), different medium and small conductance calcium-activated po
>>>
tassium channels (KCa1.1/KCNMA1 and others), as well as a voltage-dependent potassium channel (Kv1.3/KCNA3>Kv1.2/KCNA2>Kv1.6/KCNA3>>Shaker/Sh). It blocks channel activity by a simple bimolecular inhibition process.
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Potassium channel toxin alpha-KTx 1.13

 Potassium channel toxin alpha-KTx 1.13 ELISA Kit
 Potassium channel toxin alpha-KTx 1.13 Recombinant
 Potassium channel toxin alpha-KTx 1.13 Antibody
Also known as Potassium channel toxin alpha-KTx 1.13 (Charybdotoxin c) (ChTx-c).
Potent selective inhibitor of high conductance (maxi-K), different medium and small conductance calcium-activated po
>>>
tassium channels (KCa1.1/KCNMA1 and others), as well as a voltage-dependent potassium channel (Kv1.3/KCNA3>Kv1.2/KCNA2>Kv1.6/KCNA3>>Shaker/Sh). It blocks channel activity by a simple bimolecular inhibition process.
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Potassium channel toxin alpha-KTx 1.14

 Potassium channel toxin alpha-KTx 1.14 ELISA Kit
 Potassium channel toxin alpha-KTx 1.14 Recombinant
 Potassium channel toxin alpha-KTx 1.14 Antibody
Also known as Potassium channel toxin alpha-KTx 1.14 (BmKcug1) (Kcug1).
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1.1/KCNMA1) and voltage-gated potassium cha
>>>
nnels (Kv1.3/KCNA3 and ERG1/Kv11.1/KCNH2).
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Potassium channel toxin alpha-KTx 1.15

 Potassium channel toxin alpha-KTx 1.15 ELISA Kit
 Potassium channel toxin alpha-KTx 1.15 Recombinant
 Potassium channel toxin alpha-KTx 1.15 Antibody
Also known as Potassium channel toxin alpha-KTx 1.15 (BmKcug2) (Kcug1).
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1.1/KCNMA1) and voltage-gated potassium cha
>>>
nnels (Kv1.3/KCNA3).
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Potassium channel toxin alpha-KTx 1.16

 Potassium channel toxin alpha-KTx 1.16 ELISA Kit
 Potassium channel toxin alpha-KTx 1.16 Recombinant
 Potassium channel toxin alpha-KTx 1.16 Antibody
Also known as Potassium channel toxin alpha-KTx 1.16 (Toxin MeKTx11-1).
Inhibits voltage-gated potassium channel rKv1.1/KCNA1 at nanomolar ranges (IC50=780 +-60 nM, no inhibition observed at 50 nM)
>>>
.
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Potassium channel toxin alpha-KTx 1.17

 Potassium channel toxin alpha-KTx 1.17 ELISA Kit
 Potassium channel toxin alpha-KTx 1.17 Recombinant
 Potassium channel toxin alpha-KTx 1.17 Antibody
Also known as Potassium channel toxin alpha-KTx 1.17 (Toxin MeKTx11-3).
Inhibits voltage-gated potassium channel rKv1.1/KCNA1 at nanomolar ranges (IC50=135 +- 10 nM, reduction of current by 20% at
>>>
50 nM of toxin).
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Potassium channel toxin alpha-KTx 1.2

 Potassium channel toxin alpha-KTx 1.2 ELISA Kit
 Potassium channel toxin alpha-KTx 1.2 Recombinant
 Potassium channel toxin alpha-KTx 1.2 Antibody
Also known as Potassium channel toxin alpha-KTx 1.2 (ChTX-Lq2) (ChTx-d) (Charybdotoxin-2) (ChTx-2) (Lqh 18-2) (Toxin 18-2).
Blocks calcium-activated potassium channels (Kd=43 nM on KCa1.1/KCNMA1).
>>>
Has a potent presynaptic facilitatory action, with less effect on direct muscle stimulation.
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Potassium channel toxin alpha-KTx 1.3

 Potassium channel toxin alpha-KTx 1.3 ELISA Kit
 Potassium channel toxin alpha-KTx 1.3 Recombinant
 Potassium channel toxin alpha-KTx 1.3 Antibody
Also known as Potassium channel toxin alpha-KTx 1.3 (Iberiotoxin) (IbTx).
Blocks selectively the high conductance calcium-activated (maxi-K) potassium channels (KCa1.1/KCNMA1).
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Potassium channel toxin alpha-KTx 1.4

 Potassium channel toxin alpha-KTx 1.4 ELISA Kit
 Potassium channel toxin alpha-KTx 1.4 Recombinant
 Potassium channel toxin alpha-KTx 1.4 Antibody
Also known as Potassium channel toxin alpha-KTx 1.4 (Limbatotoxin) (LbTx) (Limbatustoxin).
Blocks selectively the high conductance calcium-activated (maxi-K) potassium channels.
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Potassium channel toxin alpha-KTx 1.5

 Potassium channel toxin alpha-KTx 1.5 ELISA Kit
 Potassium channel toxin alpha-KTx 1.5 Recombinant
 Potassium channel toxin alpha-KTx 1.5 Antibody
Also known as Potassium channel toxin alpha-KTx 1.5 (BmTX1) (Neurotoxin TX1).
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1.1/KCNMA1) and voltage-gated potassi
>>>
um channels (Kv1.3/KCNA3).
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Potassium channel toxin alpha-KTx 1.6

 Potassium channel toxin alpha-KTx 1.6 ELISA Kit
 Potassium channel toxin alpha-KTx 1.6 Recombinant
 Potassium channel toxin alpha-KTx 1.6 Antibody
Also known as Potassium channel toxin alpha-KTx 1.6 (BmTX2) (Neurotoxin TX2).
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1.1/KCNMA1) and voltage-gated potassi
>>>
um channels (Kv1.3/KCNA3 and ERG1/Kv11.1/KCNH2).
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Potassium channel toxin alpha-KTx 1.9

 Potassium channel toxin alpha-KTx 1.9 ELISA Kit
 Potassium channel toxin alpha-KTx 1.9 Recombinant
 Potassium channel toxin alpha-KTx 1.9 Antibody
Also known as Potassium channel toxin alpha-KTx 1.9 (Hongotoxin-2) (HgTX2).
Potent selective inhibitor of Kv1/KCNA voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 10.1

 Potassium channel toxin alpha-KTx 10.1 ELISA Kit
 Potassium channel toxin alpha-KTx 10.1 Recombinant
 Potassium channel toxin alpha-KTx 10.1 Antibody
Also known as Potassium channel toxin alpha-KTx 10.1 (Cobatoxin-1) (CoTx1) (gtIX).
Blocks Shaker B (Sh) and voltage-gated potassium-channels Kv1.1/KCNA1, Kv1.2/KCNA2, Kv1.3/KCNA3. Also inhibits sma
>>>
ll conductance calcium-activated potassium channels (KCNN) and intermediate conductance calcium-activated potassium channel (KCa3.1/KCNN4).
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Potassium channel toxin alpha-KTx 10.2

 Potassium channel toxin alpha-KTx 10.2 ELISA Kit
 Potassium channel toxin alpha-KTx 10.2 Recombinant
 Potassium channel toxin alpha-KTx 10.2 Antibody
Also known as Potassium channel toxin alpha-KTx 10.2 (Cobatoxin-2) (CoTx2).
Blocks Shaker B potassium-channels (Kv1.1/KCNA1 sub-family).
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Potassium channel toxin alpha-KTx 10.4

 Potassium channel toxin alpha-KTx 10.4 ELISA Kit
 Potassium channel toxin alpha-KTx 10.4 Recombinant
 Potassium channel toxin alpha-KTx 10.4 Antibody
Blocks human voltage-gated potassium channel Kv1.2/KCNA2 (IC50=3.6 nM) and Kv1.3/KCNA3 (IC50=72 nM).
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Potassium channel toxin alpha-KTx 11.1

 Potassium channel toxin alpha-KTx 11.1 ELISA Kit
 Potassium channel toxin alpha-KTx 11.1 Recombinant
 Potassium channel toxin alpha-KTx 11.1 Antibody
Also known as Potassium channel toxin alpha-KTx 11.1 (Parabutoxin-1) (PBTx1).
Binds and inhibits voltage-sensitive potassium channels. Inhibits the vertebrate potassium channels Kv1.1/KCNA1, Kv1.2/
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KCNA2 and Kv1.3/KCNA3 with low affinity. Also weakly inhibits Kv7.1/KCNQ1 (10 µM of the toxin inhibits currents by 21.43%).
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Potassium channel toxin alpha-KTx 11.2

 Potassium channel toxin alpha-KTx 11.2 ELISA Kit
 Potassium channel toxin alpha-KTx 11.2 Recombinant
 Potassium channel toxin alpha-KTx 11.2 Antibody
Also known as Potassium channel toxin alpha-KTx 11.2 (Parabutoxin-2) (PBTx2).
Binds and inhibits voltage-sensitive potassium channels. Inhibits the vertebrate potassium channel Kv1.1/KCNA1 with low
>>>
affinity.
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Potassium channel toxin alpha-KTx 11.3

 Potassium channel toxin alpha-KTx 11.3 ELISA Kit
 Potassium channel toxin alpha-KTx 11.3 Recombinant
 Potassium channel toxin alpha-KTx 11.3 Antibody
Also known as Potassium channel toxin alpha-KTx 11.3 (Parabutoxin-10) (PBTx10).
Binds and inhibits voltage-sensitive potassium channels. Inhibits the vertebrate potassium channel Kv1.1/KCNA1 with l
>>>
ow affinity.
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Potassium channel toxin alpha-KTx 12.1

 Potassium channel toxin alpha-KTx 12.1 ELISA Kit
 Potassium channel toxin alpha-KTx 12.1 Recombinant
 Potassium channel toxin alpha-KTx 12.1 Antibody
Also known as Potassium channel toxin alpha-KTx 12.1 (Butantoxin) (BuTX) (Ts6) (TsTX-IV).
Potently blocks Kv1.3/KCNA3, Kv1.2/KCNA2, and Shaker potassium channels (PubMed:24590385) and inhibits high
>>>
conductance calcium-activated potassium channels (PubMed:10082164). The IC50 of Kv1.3/KCNN3 and Kv1.2/KCNN2 are 0.55 nM and 6.19 nM respectively (PubMed:24590385). In addition, it stimulates the release of NO, IL-6 and TNF-alpha in J774.1 cells (PubMed:21549737) and presents a pro-inflammatory activity in mice (PubMed:23085190).
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Potassium channel toxin alpha-KTx 12.2

 Potassium channel toxin alpha-KTx 12.2 ELISA Kit
 Potassium channel toxin alpha-KTx 12.2 Recombinant
 Potassium channel toxin alpha-KTx 12.2 Antibody
Also known as Potassium channel toxin alpha-KTx 12.2 (Butantoxin) (BuTX) (TtBut).
Inhibits high conductance calcium-activated potassium channels (). Reversibly inhibits Shaker B potassium channels.
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Potassium channel toxin alpha-KTx 12.3

 Potassium channel toxin alpha-KTx 12.3 ELISA Kit
 Potassium channel toxin alpha-KTx 12.3 Recombinant
 Potassium channel toxin alpha-KTx 12.3 Antibody
Also known as Potassium channel toxin alpha-KTx 12.3 (Butantoxin-like peptide) (Tco30).
Inhibits high conductance calcium-activated potassium channels (KCNMA) (). Inhibits Shaker B potassium channe
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ls.
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Potassium channel toxin alpha-KTx 12.4

 Potassium channel toxin alpha-KTx 12.4 ELISA Kit
 Potassium channel toxin alpha-KTx 12.4 Recombinant
 Potassium channel toxin alpha-KTx 12.4 Antibody
Also known as Potassium channel toxin alpha-KTx 12.4 (Butantoxin) (BuTX) (TstBut).
Inhibits high conductance calcium-activated potassium channels. Reversibly inhibits Shaker B potassium channels ()
>>>
.
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Potassium channel toxin alpha-KTx 12.5

 Potassium channel toxin alpha-KTx 12.5 ELISA Kit
 Potassium channel toxin alpha-KTx 12.5 Recombinant
 Potassium channel toxin alpha-KTx 12.5 Antibody
Also known as Potassium channel toxin alpha-KTx 12.5 (Toxin alpha-KTx10) (LmKTx10).
This recombinant toxin inhibits the mammalian voltage-gated potassium channels Kv1.3/KCNA3 in vitro with an IC50
>>>
of 28 nM. Kv1.1/KCNA1 and Kv1.2/KCNA2 potassium channels are also weakly inhibited (IC50= 1.73 µM and IC50=12.63 µM).
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Potassium channel toxin alpha-KTx 13.1

 Potassium channel toxin alpha-KTx 13.1 ELISA Kit
 Potassium channel toxin alpha-KTx 13.1 Recombinant
 Potassium channel toxin alpha-KTx 13.1 Antibody
Also known as Potassium channel toxin alpha-KTx 13.1 (Toxin Tc1) (Toxin To1).
Blocks reversibly Shaker B potassium channels. Also displaces binding of noxiustoxin to mouse brain synaptosome membran
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es.
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Potassium channel toxin alpha-KTx 13.2

 Potassium channel toxin alpha-KTx 13.2 ELISA Kit
 Potassium channel toxin alpha-KTx 13.2 Recombinant
 Potassium channel toxin alpha-KTx 13.2 Antibody
Also known as Potassium channel toxin alpha-KTx 13.2 (OsK-2) (OsK2).
Potent and selective inhibitor of Kv1.2/KCNA2 potassium channels.
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Potassium channel toxin alpha-KTx 13.3

 Potassium channel toxin alpha-KTx 13.3 ELISA Kit
 Potassium channel toxin alpha-KTx 13.3 Recombinant
 Potassium channel toxin alpha-KTx 13.3 Antibody
Also known as Potassium channel toxin alpha-KTx 13.3 (Toxin Tpa1).
Reversibly blocks Shaker B potassium channels, with a dissociation constant of 200 nM.
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Potassium channel toxin alpha-KTx 13.4

 Potassium channel toxin alpha-KTx 13.4 ELISA Kit
 Potassium channel toxin alpha-KTx 13.4 Recombinant
 Potassium channel toxin alpha-KTx 13.4 Antibody
Also known as Potassium channel toxin alpha-KTx 13.4 (Toxin Tst-17).
Blocks the potassium channel Shaker B.
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Potassium channel toxin alpha-KTx 14.1

 Potassium channel toxin alpha-KTx 14.1 ELISA Kit
 Potassium channel toxin alpha-KTx 14.1 Recombinant
 Potassium channel toxin alpha-KTx 14.1 Antibody
Also known as Potassium channel toxin alpha-KTx 14.1 (BmKK1) (Toxin Kk1).
Potential blocker of potassium channels.
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Potassium channel toxin alpha-KTx 14.2

 Potassium channel toxin alpha-KTx 14.2 ELISA Kit
 Potassium channel toxin alpha-KTx 14.2 Recombinant
 Potassium channel toxin alpha-KTx 14.2 Antibody
Also known as Potassium channel toxin alpha-KTx 14.2 (BmKK2) (BmTXKS3) (KK1) (Neurotoxin BmP07) (Potassium ion channel blocker P07) (Toxin Kk2).
Inhibits potassium channels. May be active towards s
>>>
mall conductance calcium-activated potassium channels (KCNN, SK), and less active towards voltage-gated potassium channels (Kv/KCN).
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Potassium channel toxin alpha-KTx 14.3

 Potassium channel toxin alpha-KTx 14.3 ELISA Kit
 Potassium channel toxin alpha-KTx 14.3 Recombinant
 Potassium channel toxin alpha-KTx 14.3 Antibody
Also known as Potassium channel toxin alpha-KTx 14.3 (BmKK3) (Kk3) (Neurotoxin SKTx2) (Toxin KK2).
Potential blocker of potassium channels.
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Potassium channel toxin alpha-KTx 14.4

 Potassium channel toxin alpha-KTx 14.4 ELISA Kit
 Potassium channel toxin alpha-KTx 14.4 Recombinant
 Potassium channel toxin alpha-KTx 14.4 Antibody
Also known as Potassium channel toxin alpha-KTx 14.4 (BmSKTx1) (Neurotoxin SKTx1).
Selectively and reversibly inhibits small conductance calcium-activated potassium channels (KCNN, SK).
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Potassium channel toxin alpha-KTx 14.5

 Potassium channel toxin alpha-KTx 14.5 ELISA Kit
 Potassium channel toxin alpha-KTx 14.5 Recombinant
 Potassium channel toxin alpha-KTx 14.5 Antibody
Also known as Potassium channel toxin alpha-KTx 14.5 (Toxin Mgib29).
Inhibits potassium channels. May be active towards small conductance calcium-activated potassium channels (KCNN, SK), and less a
>>>
ctive towards voltage-gated potassium channels (Kv/KCN).
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Potassium channel toxin alpha-KTx 14.x

 Potassium channel toxin alpha-KTx 14.x ELISA Kit
 Potassium channel toxin alpha-KTx 14.x Recombinant
 Potassium channel toxin alpha-KTx 14.x Antibody
Also known as Potassium channel toxin alpha-KTx 14.x (BmKK14).
Potassium channels inhibitor.
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Potassium channel toxin alpha-KTx 15.1

 Potassium channel toxin alpha-KTx 15.1 ELISA Kit
 Potassium channel toxin alpha-KTx 15.1 Recombinant
 Potassium channel toxin alpha-KTx 15.1 Antibody
Also known as Potassium channel toxin alpha-KTx 15.1 (Peptide Aa1).
Blocker of voltage-gated potassium channels (600 nM of the toxin induces a block of 25% of hERG currents) (PubMed:18687312). In a
>>>
dult rat brain, it blocks the transient potassium channels in cerebellum granular cells. Blocks potassium channels by a simple 'plugging mechanism', in which a single toxin molecule finds a specific receptor site in the external vestibule of the potassium channel and thereby occludes the outer entry to the potassium conducting pore (PubMed:11018665).
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Potassium channel toxin alpha-KTx 15.2

 Potassium channel toxin alpha-KTx 15.2 ELISA Kit
 Potassium channel toxin alpha-KTx 15.2 Recombinant
 Potassium channel toxin alpha-KTx 15.2 Antibody
Also known as Potassium channel toxin alpha-KTx 15.2 (BmTX3) (BmTX3A).
Blocks both human ERG1/Kv11.1/KCNH2 potassium channels (in a reversible manner) (PubMed:14599291) and A-type voltage-gated pot
>>>
assium channels (in an irreversible manner) (PubMed:11457451, PubMed:12473099, PubMed:12637022). May dispose of two functional faces (A and B); the two basic residues (Arg-40 and Lys-41) on the alpha-helix side of the peptide that blocks the hERG current (face A) and the typical dyad through which it blocks A-type currents on the beta-sheet side (face B) (PubMed:14599291). In adult rat brain, it binds to sites in the striatum, hippocampus, superior colliculus, and cerebellum. It shares the same target in rat brain than AaTX1 (AC Q867F4) and AmmTX3 (AC P60208).
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Potassium channel toxin alpha-KTx 15.3

 Potassium channel toxin alpha-KTx 15.3 ELISA Kit
 Potassium channel toxin alpha-KTx 15.3 Recombinant
 Potassium channel toxin alpha-KTx 15.3 Antibody
Also known as Potassium channel toxin alpha-KTx 15.3 (Toxin AmmTX3).
Blocker of A-type voltage-gated potassium channels of striated neurons (PubMed:12473099). Has been shown to block ERG1/Kv11.1/KC
>>>
NH2 potassium channels (IC50=7.9 µM) (PubMed:18687312). In adult rat brain, it binds to sites in the striatum, and cerebellum. It shares the same target in rat brain than AaTX1 (AC Q867F4) and BmTX3 (AC Q8I0L5).
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Potassium channel toxin alpha-KTx 15.4

 Potassium channel toxin alpha-KTx 15.4 ELISA Kit
 Potassium channel toxin alpha-KTx 15.4 Recombinant
 Potassium channel toxin alpha-KTx 15.4 Antibody
Also known as Potassium channel toxin alpha-KTx 15.4 (AaTX1) (Toxin Aa1).
Blocker of A-type voltage-gated potassium channels of cerebellar granular cells. The occlusion of the outer entry of the K+
>>>
conducting pore is partially reversible and affects both open and closed channels. It shares the same target in rat brain than BmTX3 (AC Q8I0L5) and AmmTX3 (AC P60208).
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Potassium channel toxin alpha-KTx 15.5

 Potassium channel toxin alpha-KTx 15.5 ELISA Kit
 Potassium channel toxin alpha-KTx 15.5 Recombinant
 Potassium channel toxin alpha-KTx 15.5 Antibody
Also known as Potassium channel toxin alpha-KTx 15.5 (Toxin AaTX2).
Binds to potassium channel and affects the potassium ion currents, by occluding the outer entry to the K+ conducting pore. The bl
>>>
ockade is partially reversible and affect both open and closed channels ().
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Potassium channel toxin alpha-KTx 15.6

 Potassium channel toxin alpha-KTx 15.6 ELISA Kit
 Potassium channel toxin alpha-KTx 15.6 Recombinant
 Potassium channel toxin alpha-KTx 15.6 Antibody
Also known as Potassium channel toxin alpha-KTx 15.6 (Discrepin).
Irreversibly blocks the A-type voltage-gated potassium channels in rat cerebellum granular cells (190 nM induce 50% inhibitory effe
>>>
ct, PubMed:15369825) (IC50=190 nM, PubMed:18280256).
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Potassium channel toxin alpha-KTx 15.7

 Potassium channel toxin alpha-KTx 15.7 ELISA Kit
 Potassium channel toxin alpha-KTx 15.7 Recombinant
 Potassium channel toxin alpha-KTx 15.7 Antibody
Also known as Potassium channel toxin alpha-KTx 15.7 (Neurotoxin AamTX).
Binds to potassium channel and affects the potassium ion currents, by occluding the outer entry to the K+ conducting pore. The blockade is partially reversible and affect both open and closed channels ().
 tx1 ELISA Kit
 tx1 Recombinant
 tx1 Antibody
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Potassium channel toxin alpha-KTx 15.8

 Potassium channel toxin alpha-KTx 15.8 ELISA Kit
 Potassium channel toxin alpha-KTx 15.8 Recombinant
 Potassium channel toxin alpha-KTx 15.8 Antibody
Also known as Potassium channel toxin alpha-KTx 15.8 (BmKKx1) (Neurotoxin Kk4).
Blocker of potassium channels.
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Potassium channel toxin alpha-KTx 15.9

 Potassium channel toxin alpha-KTx 15.9 ELISA Kit
 Potassium channel toxin alpha-KTx 15.9 Recombinant
 Potassium channel toxin alpha-KTx 15.9 Antibody
Also known as Potassium channel toxin alpha-KTx 15.9 (Neurotoxin KTx9).
Inhibits voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 16.1

 Potassium channel toxin alpha-KTx 16.1 ELISA Kit
 Potassium channel toxin alpha-KTx 16.1 Recombinant
 Potassium channel toxin alpha-KTx 16.1 Antibody
Also known as Potassium channel toxin alpha-KTx 16.1 (Alpha-KTx 1.8) (Tamulotoxin) (TmTX).
Blocks calcium-activated potassium channels.
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Potassium channel toxin alpha-KTx 16.2

 Potassium channel toxin alpha-KTx 16.2 ELISA Kit
 Potassium channel toxin alpha-KTx 16.2 Recombinant
 Potassium channel toxin alpha-KTx 16.2 Antibody
Also known as Potassium channel toxin alpha-KTx 16.2 (BmK 622) (BmTx3B) (Martentoxin).
Alpha-KTx 16.2: inhibits large conductance calcium-activated potassium channels (KCa1.1/Slo-beta4 KCNMA1/KCNMB
>>>
4). It appears to block channel activity by a simple bimolecular inhibition process. Shows a fast association rate and a slow dissociation rate of binding on rat brain synaptosome (PubMed:18199674). Significantly inhibits voltage-dependent sodium current and voltage-dependent delayed rectifier potassium currents (PubMed:14632928).
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Potassium channel toxin alpha-KTx 16.3

 Potassium channel toxin alpha-KTx 16.3 ELISA Kit
 Potassium channel toxin alpha-KTx 16.3 Recombinant
 Potassium channel toxin alpha-KTx 16.3 Antibody
Also known as Potassium channel toxin alpha-KTx 16.3 (Charybdotoxin-like toxin 1) (Kchtx1) (KTX1).
Blocks calcium-activated potassium channels.
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Potassium channel toxin alpha-KTx 16.4

 Potassium channel toxin alpha-KTx 16.4 ELISA Kit
 Potassium channel toxin alpha-KTx 16.4 Recombinant
 Potassium channel toxin alpha-KTx 16.4 Antibody
Also known as Potassium channel toxin alpha-KTx 16.4 (Alpha-KTx MeuTx3B) (MeuKTx-4).
Weak inhibitor of voltage-gated potassium channel hKv1.3/KCNA3.
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Potassium channel toxin alpha-KTx 16.5

 Potassium channel toxin alpha-KTx 16.5 ELISA Kit
 Potassium channel toxin alpha-KTx 16.5 Recombinant
 Potassium channel toxin alpha-KTx 16.5 Antibody
Also known as Potassium channel toxin alpha-KTx 16.5 (Lqh 15-1) (Toxin 15-1) (alpha-KTx 1.7).
Augments responses to direct muscle stimulation probably by blocking calcium-activated potassium channe
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ls.
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Potassium channel toxin alpha-KTx 16.6

 Potassium channel toxin alpha-KTx 16.6 ELISA Kit
 Potassium channel toxin alpha-KTx 16.6 Recombinant
 Potassium channel toxin alpha-KTx 16.6 Antibody
Also known as Potassium channel toxin alpha-KTx 16.6 (Toxin Tx608).
Inhibits potassium channel.
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Potassium channel toxin alpha-KTx 16.7

 Potassium channel toxin alpha-KTx 16.7 ELISA Kit
 Potassium channel toxin alpha-KTx 16.7 Recombinant
 Potassium channel toxin alpha-KTx 16.7 Antibody
Also known as Potassium channel toxin alpha-KTx 16.7 (Alpha-KTx 16.5) (MegKTx3).
May play a role in blocking voltage-gated potassium channels Kv1.2/KCNA2, and Kv1.3/KCNA3. Blocks the voltage-gated
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potassium channel Kv1.3/KCNA3, with an IC50 of 118.3 +-55.8 nM.
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Potassium channel toxin alpha-KTx 16.8

 Potassium channel toxin alpha-KTx 16.8 ELISA Kit
 Potassium channel toxin alpha-KTx 16.8 Recombinant
 Potassium channel toxin alpha-KTx 16.8 Antibody
Also known as Potassium channel toxin alpha-KTx 16.8 (Toxin BoP1).
Poorly competes with (125)I-kaliotoxin binding on rat brain synaptosome (IC50>100 nM). Is a poor Kv1.3 ligand (PubMed:23523531)
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. May have as real target KCa1.1/KCNMA1 channel (). Shows weak toxicity on mice (PubMed:23523531).
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Potassium channel toxin alpha-KTx 16.9

 Potassium channel toxin alpha-KTx 16.9 ELISA Kit
 Potassium channel toxin alpha-KTx 16.9 Recombinant
 Potassium channel toxin alpha-KTx 16.9 Antibody
Also known as Potassium channel toxin alpha-KTx 16.9 (Toxin BoP2).
Poorly competes with (125)I-kaliotoxin binding on rat brain synaptosome (IC50>100 nM). Is a poor Kv1.3/KCNA3 ligand (PubMed:235
>>>
23531). May have as real target KCa1.1/KCNMA1 channel (). Shows weak toxicity on mice (PubMed:23523531).
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Potassium channel toxin alpha-KTx 17.1

 Potassium channel toxin alpha-KTx 17.1 ELISA Kit
 Potassium channel toxin alpha-KTx 17.1 Recombinant
 Potassium channel toxin alpha-KTx 17.1 Antibody
Also known as Potassium channel toxin alpha-KTx 17.1 (BmKK4) (Toxin Kk4) (Toxin TXKs4).
Blocker of potassium channels, which inhibits both the delayed rectifier and fast transient potassium current
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. The inhibition is reversible and voltage-independent. It causes a depolarizing shift of the steady-state activation curve of the currents, without changing their steady-state inactivation behavior.
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Potassium channel toxin alpha-KTx 17.2

 Potassium channel toxin alpha-KTx 17.2 ELISA Kit
 Potassium channel toxin alpha-KTx 17.2 Recombinant
 Potassium channel toxin alpha-KTx 17.2 Antibody
Inhibits voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 18.1

 Potassium channel toxin alpha-KTx 18.1 ELISA Kit
 Potassium channel toxin alpha-KTx 18.1 Recombinant
 Potassium channel toxin alpha-KTx 18.1 Antibody
Also known as Potassium channel toxin alpha-KTx 18.1 (Toxin Tc32) (Toxin To32).
Reversible blocker of both Kv1.3/KCNA3 potassium channels (high affinity) and Shaker B (mammalian Kv1.1 analog) potas
>>>
sium channels (very low affinity).
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Potassium channel toxin alpha-KTx 18.2

 Potassium channel toxin alpha-KTx 18.2 ELISA Kit
 Potassium channel toxin alpha-KTx 18.2 Recombinant
 Potassium channel toxin alpha-KTx 18.2 Antibody
Also known as Potassium channel toxin alpha-KTx 18.2 (Toxin TdK2).
Reversibly blocks Shaker B potassium channels.
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Potassium channel toxin alpha-KTx 18.3

 Potassium channel toxin alpha-KTx 18.3 ELISA Kit
 Potassium channel toxin alpha-KTx 18.3 Recombinant
 Potassium channel toxin alpha-KTx 18.3 Antibody
Also known as Potassium channel toxin alpha-KTx 18.3 (Toxin TdK3).
Probable voltage-gated potassium channel inhibitor.
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Potassium channel toxin alpha-KTx 19.1

 Potassium channel toxin alpha-KTx 19.1 ELISA Kit
 Potassium channel toxin alpha-KTx 19.1 Recombinant
 Potassium channel toxin alpha-KTx 19.1 Antibody
Also known as Potassium channel toxin alpha-KTx 19.1 (BmK37) (Neurotoxin BmBKTx1).
Selective inhibitor of high conductance calcium-activated potassium channels KCa1.1/KCNMA1. May be insect specific
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.
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Potassium channel toxin alpha-KTx 2.1

 Potassium channel toxin alpha-KTx 2.1 ELISA Kit
 Potassium channel toxin alpha-KTx 2.1 Recombinant
 Potassium channel toxin alpha-KTx 2.1 Antibody
Also known as Potassium channel toxin alpha-KTx 2.1 (Noxiustoxin) (NTx) (Toxin II.11).
Blocks voltage-gated potassium channels (mKv1.1/KCNA1 (Kd>25 nM), rKv1.2/KCNA2 (Kd=2 nM), mKv1.3/KCNA3 (Kd=1 n
>>>
M), hKv1.5/KCNA5 (Kd>25 nM) and mKv3.1/KCNC1 (Kd>25 nM)) and calcium-activated potassium channels (KCa1.1/KCNMA1 and KCa3.1/KCNN4, Kd>25 nM).
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Potassium channel toxin alpha-KTx 2.10

 Potassium channel toxin alpha-KTx 2.10 ELISA Kit
 Potassium channel toxin alpha-KTx 2.10 Recombinant
 Potassium channel toxin alpha-KTx 2.10 Antibody
Also known as Potassium channel toxin alpha-KTx 2.10 (Toxin Ce3).
Weakly blocks Kv1.3/KCNA3 voltage-gated potassium channels (Kd is estimated to be 366 nM).
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Potassium channel toxin alpha-KTx 2.11

 Potassium channel toxin alpha-KTx 2.11 ELISA Kit
 Potassium channel toxin alpha-KTx 2.11 Recombinant
 Potassium channel toxin alpha-KTx 2.11 Antibody
Also known as Potassium channel toxin alpha-KTx 2.11 (Toxin Ce4).
Blocks Kv1.3/KCNA3 voltage-gated potassium channels of human T-lymphocytes (Kd=0.98 nM).
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Potassium channel toxin alpha-KTx 2.12

 Potassium channel toxin alpha-KTx 2.12 ELISA Kit
 Potassium channel toxin alpha-KTx 2.12 Recombinant
 Potassium channel toxin alpha-KTx 2.12 Antibody
Also known as Potassium channel toxin alpha-KTx 2.12 (Toxin Ce5).
Weakly blocks Kv1.3/KCNA3 voltage-gated potassium channels (Kd is estimated to be 69 nM).
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Potassium channel toxin alpha-KTx 2.13

 Potassium channel toxin alpha-KTx 2.13 ELISA Kit
 Potassium channel toxin alpha-KTx 2.13 Recombinant
 Potassium channel toxin alpha-KTx 2.13 Antibody
Also known as Potassium channel toxin alpha-KTx 2.13 (Toxin Css20).
Selective inhibitor of voltage-gated potassium channels, blocks the Kv1.2/KCNA2 (Kd=1.3 nM) and Kv1.3/KCNA3 (Kd=7.2 nM) channels.
>>>
Association and dissociation rates of the toxin are slower for Kv1.2/KCNA2 than for Kv1.3/KCNA3.
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Potassium channel toxin alpha-KTx 2.14

 Potassium channel toxin alpha-KTx 2.14 ELISA Kit
 Potassium channel toxin alpha-KTx 2.14 Recombinant
 Potassium channel toxin alpha-KTx 2.14 Antibody
Reversibly blocks hKv1.1/KCNA1 (50% inhibition of current at 1 µM). Seems not to be voltage-dependent.
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Potassium channel toxin alpha-KTx 2.15

 Potassium channel toxin alpha-KTx 2.15 ELISA Kit
 Potassium channel toxin alpha-KTx 2.15 Recombinant
 Potassium channel toxin alpha-KTx 2.15 Antibody
Blocks human voltage-gated potassium channels Kv1.2/KCNA2 (IC50=0.3 nM), Kv1.3/KCNA3 (IC50=8.3 nM) and Shaker IR (with inactivation domain removed) (IC50=12 nM) and blocks intermediate conductance cal
>>>
cium-activated potassium channel KCa3.1/KCNN4 (IC50=6.4 nM).
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Potassium channel toxin alpha-KTx 2.16

 Potassium channel toxin alpha-KTx 2.16 ELISA Kit
 Potassium channel toxin alpha-KTx 2.16 Recombinant
 Potassium channel toxin alpha-KTx 2.16 Antibody
Blocks human voltage-gated potassium channels Kv1.2/KCNA2 (IC50=0.7 nM), Kv1.3/KCNA3 (IC50=26.2 nM) and blocks intermediate conductance calcium-activated potassium channel KCa3.1/KCNN4 (IC50=56 nM).
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Potassium channel toxin alpha-KTx 2.17

 Potassium channel toxin alpha-KTx 2.17 ELISA Kit
 Potassium channel toxin alpha-KTx 2.17 Recombinant
 Potassium channel toxin alpha-KTx 2.17 Antibody
Blocks human voltage-gated potassium channels Kv1.1/KCNA1 (IC50=4.8 nM) and Kv1.2/KCNA2 (IC50=2.9 nM).
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Potassium channel toxin alpha-KTx 2.2

 Potassium channel toxin alpha-KTx 2.2 ELISA Kit
 Potassium channel toxin alpha-KTx 2.2 Recombinant
 Potassium channel toxin alpha-KTx 2.2 Antibody
Also known as Potassium channel toxin alpha-KTx 2.2 (Margatoxin) (MgTX).
Potent inhibitor of voltage-gated potassium channels such as Kv1.1/KCNA1 (IC50=0.144 nM), Kv1.2/KCNA2 (IC50=0.675 nM), Kv1.3
>>>
/KCNA3 (IC50=0.23 nM) and Shaker (Kd=160 nM).
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Potassium channel toxin alpha-KTx 2.3

 Potassium channel toxin alpha-KTx 2.3 ELISA Kit
 Potassium channel toxin alpha-KTx 2.3 Recombinant
 Potassium channel toxin alpha-KTx 2.3 Antibody
Also known as Potassium channel toxin alpha-KTx 2.3 (C.1.limpidus toxin 1) (CllTx1) (Toxin II.10.9.1).
Inhibitor of voltage-gated potassium channels (Kv). It is capable of displacing the binding of
>>>
radio-labeled noxiustoxin (AC P08815) to rat brain synaptosomes with high affinity (about 100 pM). It is also capable of inhibiting transient potassium-currents (resembling I(A)-type currents), in cultured rat cerebellar granule cells. About 50% of the peak currents are reduced by application of a 1.5 µM solution of this toxin.
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Potassium channel toxin alpha-KTx 2.4

 Potassium channel toxin alpha-KTx 2.4 ELISA Kit
 Potassium channel toxin alpha-KTx 2.4 Recombinant
 Potassium channel toxin alpha-KTx 2.4 Antibody
Also known as Potassium channel toxin alpha-KTx 2.4 (Noxiustoxin-2) (NTx2).
Blocks voltage-gated non-inactivating potassium channels (Kv) and unblocks inactivating potassium channels blocked by alp
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ha-dendrotoxin in synaptosomes. It is not toxic to mice and crustaceans, but has a paralysing effect on crickets.
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Potassium channel toxin alpha-KTx 2.5

 Potassium channel toxin alpha-KTx 2.5 ELISA Kit
 Potassium channel toxin alpha-KTx 2.5 Recombinant
 Potassium channel toxin alpha-KTx 2.5 Antibody
Also known as Potassium channel toxin alpha-KTx 2.5 (Hongotoxin-1) (HgTX1).
Potent selective inhibitor of Kv1.1/KCNA1, Kv1.2/KCNA2, Kv1.3/KCNA3 voltage-gated potassium channels. Weak inhibitor of K
>>>
v1.6/KCNA6 potassium channel.
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Potassium channel toxin alpha-KTx 2.6

 Potassium channel toxin alpha-KTx 2.6 ELISA Kit
 Potassium channel toxin alpha-KTx 2.6 Recombinant
 Potassium channel toxin alpha-KTx 2.6 Antibody
Also known as Potassium channel toxin alpha-KTx 2.6 (Hongotoxin-3) (HgTX3).
Potent inhibitor of Kv1/KCNA voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 2.7

 Potassium channel toxin alpha-KTx 2.7 ELISA Kit
 Potassium channel toxin alpha-KTx 2.7 Recombinant
 Potassium channel toxin alpha-KTx 2.7 Antibody
Also known as Potassium channel toxin alpha-KTx 2.7 (C.1.limpidus toxin 2) (CllTx2) (Toxin II.10.9.2).
Inhibitor of voltage-gated potassium channels (Kv). This protein is capable of displacing the
>>>
binding of radio-labeled noxiustoxin (AC P08815) to rat brain synaptosomes with high affinity (about 100 pM). It is also capable of inhibiting transient potassium-currents (resembling I(A)-type currents), in cultured rat cerebellar granule cells. About 50% of the peak currents are reduced by application of a 1.5 µM solution of this toxin. Is lethal to mice (when less than 100 µg are injected).
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Potassium channel toxin alpha-KTx 2.8

 Potassium channel toxin alpha-KTx 2.8 ELISA Kit
 Potassium channel toxin alpha-KTx 2.8 Recombinant
 Potassium channel toxin alpha-KTx 2.8 Antibody
Also known as Potassium channel toxin alpha-KTx 2.8 (Toxin Ce1).
Blocks Kv1.3/KCNA3 voltage-gated potassium channels of human T-lymphocytes (Kd=0.71 nM).
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Potassium channel toxin alpha-KTx 2.9

 Potassium channel toxin alpha-KTx 2.9 ELISA Kit
 Potassium channel toxin alpha-KTx 2.9 Recombinant
 Potassium channel toxin alpha-KTx 2.9 Antibody
Also known as Potassium channel toxin alpha-KTx 2.9 (Toxin Ce2).
Blocks Kv1.3/KCNA3 voltage-gated potassium channels of human T-lymphocytes (Kd=0.25 nM).
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Potassium channel toxin alpha-KTx 20.1

 Potassium channel toxin alpha-KTx 20.1 ELISA Kit
 Potassium channel toxin alpha-KTx 20.1 Recombinant
 Potassium channel toxin alpha-KTx 20.1 Antibody
Also known as Potassium channel toxin alpha-KTx 20.1 (Toxin Tt28).
Reduces potassium currents through Kv1.2/KCNA2 and Kv1.3/KCNA3 voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 21.1

 Potassium channel toxin alpha-KTx 21.1 ELISA Kit
 Potassium channel toxin alpha-KTx 21.1 Recombinant
 Potassium channel toxin alpha-KTx 21.1 Antibody
Also known as Potassium channel toxin alpha-KTx 21.1 (Tityustoxin-15) (Ts15).
Reversibly and voltage-independently blocks voltage-gated potassium channels rKv1.2/KCNA2 (73%) (IC50=196 nM), hKv1.3/K
>>>
CNA3 (50%) (IC50=508 nM), Shaker IR (30%), rKv1.6/KCNA6 (22%) (at 0.5 µM). Interaction of Ts15 with Kv1.3/KCNA3 is stronger than its interaction with Kv1.2/KCNA2.
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Potassium channel toxin alpha-KTx 22.1

 Potassium channel toxin alpha-KTx 22.1 ELISA Kit
 Potassium channel toxin alpha-KTx 22.1 Recombinant
 Potassium channel toxin alpha-KTx 22.1 Antibody
Also known as Potassium channel toxin alpha-KTx 22.1 (Neurotoxin BmK38) (Toxin Kcugx).
May block potassium channels.
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Potassium channel toxin alpha-KTx 23.1

 Potassium channel toxin alpha-KTx 23.1 ELISA Kit
 Potassium channel toxin alpha-KTx 23.1 Recombinant
 Potassium channel toxin alpha-KTx 23.1 Antibody
Also known as Potassium channel toxin alpha-KTx 23.1 (Toxin Vm24) (Toxin alpha-KTx 21.1).
Selectively and irreversibly binds (K(d)=2.9 pM) and blocks hKv1.3/KCNA3 potassium channels of human T-lymp
>>>
hocytes. Weakly blocks hKCa3.1/KCNN4, mKv1.1/KCNA1, and hKv1.2/KCNA2 channels. In vivo, high doses (200 µg) produce no symptoms of intoxication when injected into mice.
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Potassium channel toxin alpha-KTx 23.2

 Potassium channel toxin alpha-KTx 23.2 ELISA Kit
 Potassium channel toxin alpha-KTx 23.2 Recombinant
 Potassium channel toxin alpha-KTx 23.2 Antibody
Also known as Potassium channel toxin alpha-KTx 23.2 (Toxin Vm23) (Toxin alpha-KTx 21.2).
Selectively and irreversibly binds (K(d)=2.9 pM) and blocks Kv1.3/KCNA3 potassium channels of human T-lymph
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ocytes. Weakly blocks Kv1.2/KCNA2 (9%).
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Potassium channel toxin alpha-KTx 26.3

 Potassium channel toxin alpha-KTx 26.3 ELISA Kit
 Potassium channel toxin alpha-KTx 26.3 Recombinant
 Potassium channel toxin alpha-KTx 26.3 Antibody
Also known as Potassium channel toxin alpha-KTx 26.3 (Toxin Mgib2).
Recombinant toxin that reversibly inhibits the potassium current of mKv1.3/KCNA3 channel stably expressed in COS7 cells (IC50=150
>>>
nM).
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Potassium channel toxin alpha-KTx 27.1

 Potassium channel toxin alpha-KTx 27.1 ELISA Kit
 Potassium channel toxin alpha-KTx 27.1 Recombinant
 Potassium channel toxin alpha-KTx 27.1 Antibody
Also known as Potassium channel toxin alpha-KTx 27.1 (Toxin BoiTx771) (Toxin Tx771).
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Potassium channel toxin alpha-KTx 27.2

 Potassium channel toxin alpha-KTx 27.2 ELISA Kit
 Potassium channel toxin alpha-KTx 27.2 Recombinant
 Potassium channel toxin alpha-KTx 27.2 Antibody
Also known as Potassium channel toxin alpha-KTx 27.2 (Putative neurotoxin-B).
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Potassium channel toxin alpha-KTx 27.3

 Potassium channel toxin alpha-KTx 27.3 ELISA Kit
 Potassium channel toxin alpha-KTx 27.3 Recombinant
 Potassium channel toxin alpha-KTx 27.3 Antibody
Also known as Potassium channel toxin alpha-KTx 27.3 (Putative neurotoxin-C).
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Potassium channel toxin alpha-KTx 27.4

 Potassium channel toxin alpha-KTx 27.4 ELISA Kit
 Potassium channel toxin alpha-KTx 27.4 Recombinant
 Potassium channel toxin alpha-KTx 27.4 Antibody
Also known as Potassium channel toxin alpha-KTx 27.4 (Toxin Mgib23).
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Potassium channel toxin alpha-KTx 3.1

 Potassium channel toxin alpha-KTx 3.1 ELISA Kit
 Potassium channel toxin alpha-KTx 3.1 Recombinant
 Potassium channel toxin alpha-KTx 3.1 Antibody
Also known as Potassium channel toxin alpha-KTx 3.1 (Kaliotoxin) (KTX) (Kaliotoxin-1) (KTX-1).
Potent inhibitor voltage-gated potassium channels Kv1.3/KCNA3 (Kd=0.65 nM) and Kv1.1/KCNA1 (Kd=41 nM)
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(PubMed:7517498). It appears to block channel activity by a simple bimolecular inhibition process. Induces a transient period of fast flickering in the channel openings, followed by an almost complete blockade of the channel. Its binding affinity to rat brain synaptosomes is 5-fold higher than this of KTX-3. Binding of the toxin to the channel is associated with significant structural rearrangements in both molecules.
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Potassium channel toxin alpha-KTx 3.10

 Potassium channel toxin alpha-KTx 3.10 ELISA Kit
 Potassium channel toxin alpha-KTx 3.10 Recombinant
 Potassium channel toxin alpha-KTx 3.10 Antibody
Also known as Potassium channel toxin alpha-KTx 3.10 (BoiTx1).
Inhibits insect potassium channel. Is at least a hundred-fold more potent against the Drosophila Shaker channel than towards its mamma
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lian homologs Kv1.1/KCNA1 and Kv1.3/KCNA3.
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Potassium channel toxin alpha-KTx 3.11

 Potassium channel toxin alpha-KTx 3.11 ELISA Kit
 Potassium channel toxin alpha-KTx 3.11 Recombinant
 Potassium channel toxin alpha-KTx 3.11 Antibody
Also known as Potassium channel toxin alpha-KTx 3.11 (OdK2).
Blocks the voltage-gated potassium channel Kv1.3/KCNA3, with an IC50 of 7.2 nM.
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Potassium channel toxin alpha-KTx 3.12

 Potassium channel toxin alpha-KTx 3.12 ELISA Kit
 Potassium channel toxin alpha-KTx 3.12 Recombinant
 Potassium channel toxin alpha-KTx 3.12 Antibody
Also known as Potassium channel toxin alpha-KTx 3.12 (Kaliotoxin analog) (Aam-KTX).
Potent inhibitor of voltage-dependent potassium channels, with a preference for Kv1.3/KCNA3 versus Kv1.2/KCNA2.
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Potassium channel toxin alpha-KTx 3.13

 Potassium channel toxin alpha-KTx 3.13 ELISA Kit
 Potassium channel toxin alpha-KTx 3.13 Recombinant
 Potassium channel toxin alpha-KTx 3.13 Antibody
Also known as Potassium channel toxin alpha-KTx 3.13 (MeuKTx).
Blocks voltage-gated potassium channels Kv1.1/KCNA1 (IC50=203.15 pM), Kv1.2/KCNA2 (IC50=8.92 nM) from rat and human Kv1.3 KCNA3/KCNA3
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(IC50=171 pM) potently. At 2 µM, also blocks Shaker IR and has a moderate effect on rat Kv1.6/KCNA6.
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Potassium channel toxin alpha-KTx 3.15

 Potassium channel toxin alpha-KTx 3.15 ELISA Kit
 Potassium channel toxin alpha-KTx 3.15 Recombinant
 Potassium channel toxin alpha-KTx 3.15 Antibody
Also known as Potassium channel toxin alpha-KTx 3.15 (MegKTx1).
May play a role in blocking voltage-gated potassium channels Kv1.1/KCNA1, Kv1.3/KCNA3 and Kv1.6/KCNA6.
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Potassium channel toxin alpha-KTx 3.16

 Potassium channel toxin alpha-KTx 3.16 ELISA Kit
 Potassium channel toxin alpha-KTx 3.16 Recombinant
 Potassium channel toxin alpha-KTx 3.16 Antibody
Also known as Potassium channel toxin alpha-KTx 3.16 (MegKTx4) (Tx4).
Potassium channel inibitor.
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Potassium channel toxin alpha-KTx 3.17

 Potassium channel toxin alpha-KTx 3.17 ELISA Kit
 Potassium channel toxin alpha-KTx 3.17 Recombinant
 Potassium channel toxin alpha-KTx 3.17 Antibody
Also known as Potassium channel toxin alpha-KTx 3.17 (Toxin BoPKTX).
Completely inhibits the (125)I-kaliotoxin binding on rat brain synaptosomes with high-affinity (IC50=0.1 nM). Is a potent Kv1.3/
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KCNA3 ligand.
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Potassium channel toxin alpha-KTx 3.18

 Potassium channel toxin alpha-KTx 3.18 ELISA Kit
 Potassium channel toxin alpha-KTx 3.18 Recombinant
 Potassium channel toxin alpha-KTx 3.18 Antibody
Also known as Potassium channel toxin alpha-KTx 3.18 (Toxin MeKTx13-2).
Inhibits voltage-gated potassium channel rKv1.1/KCNA1 at nanomolar ranges (IC50=90 +-2 nM, reduction of current by 30% at 50
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nM or toxin).
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Potassium channel toxin alpha-KTx 3.19

 Potassium channel toxin alpha-KTx 3.19 ELISA Kit
 Potassium channel toxin alpha-KTx 3.19 Recombinant
 Potassium channel toxin alpha-KTx 3.19 Antibody
Also known as Potassium channel toxin alpha-KTx 3.19 (Toxin MeKTx13-3).
Inhibits voltage-gated potassium channel rKv1.1/KCNA1 at nanomolar ranges (IC50=1.9 +-0.2 nM, 100% inhibition at 50 nM of tox
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in).
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Potassium channel toxin alpha-KTx 3.2

 Potassium channel toxin alpha-KTx 3.2 ELISA Kit
 Potassium channel toxin alpha-KTx 3.2 Recombinant
 Potassium channel toxin alpha-KTx 3.2 Antibody
Also known as Potassium channel toxin alpha-KTx 3.2 (Agitoxin-2) (AgTx-2) (AgTx2).
Potent inhibitor of the Shaker potassium channels and its mammalian homologs (Kv1.1/KCNA1, Kv1.3/KCNA3, Kv1.6/KCNA
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6) (Ki<1 nM for all channels) (PubMed:8204618, PubMed:20007782). Also blocks Kv1.2/KCNA2 (IC50=26.8 nM) (PubMed:8204618, PubMed:20007782).
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Potassium channel toxin alpha-KTx 3.3

 Potassium channel toxin alpha-KTx 3.3 ELISA Kit
 Potassium channel toxin alpha-KTx 3.3 Recombinant
 Potassium channel toxin alpha-KTx 3.3 Antibody
Also known as Potassium channel toxin alpha-KTx 3.3 (Agitoxin-3) (AgTx-3) (AgTx3).
Potent inhibitor of shaker potassium channels as well as the mammalian homologs of shaker.
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Potassium channel toxin alpha-KTx 3.4

 Potassium channel toxin alpha-KTx 3.4 ELISA Kit
 Potassium channel toxin alpha-KTx 3.4 Recombinant
 Potassium channel toxin alpha-KTx 3.4 Antibody
Also known as Potassium channel toxin alpha-KTx 3.4 (Agitoxin-1) (AgTx-1) (AgTx1) (Leiurotoxin II) (LeTx II) (Leiurotoxin-2).
Potent inhibitor of the Shaker potassium channel (Ki=0.16 nM) and its m
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ammalian homologs (Kv1.3/KCNA3 (Ki=1.7 nM), Kv1.1/KCNA1 (Ki=136 nM), Kv1.6/KCNA6 (Ki=149 nM)).
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Potassium channel toxin alpha-KTx 3.5

 Potassium channel toxin alpha-KTx 3.5 ELISA Kit
 Potassium channel toxin alpha-KTx 3.5 Recombinant
 Potassium channel toxin alpha-KTx 3.5 Antibody
Also known as Potassium channel toxin alpha-KTx 3.5 (Kaliotoxin-2) (KTX-2).
Binds and inhibits dendrotoxin sensitive voltage-dependent potassium channels and calcium-activated potassium channels.
 KTX2 ELISA Kit
 KTX2 Recombinant
 KTX2 Antibody
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Potassium channel toxin alpha-KTx 3.6

 Potassium channel toxin alpha-KTx 3.6 ELISA Kit
 Potassium channel toxin alpha-KTx 3.6 Recombinant
 Potassium channel toxin alpha-KTx 3.6 Antibody
Also known as Potassium channel toxin alpha-KTx 3.6 (BmKTX).
Blocks voltage-gated potassium channels. At 2 µM, blocks rat Kv1.1/KCNA1 and Kv1.3/KCNA3, has a strong effect on rat Kv1.2/KCNA2 and Kv
>>>
1.6/KCNA6 as well as a moderate effect on Shaker IR.
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Potassium channel toxin alpha-KTx 3.7

 Potassium channel toxin alpha-KTx 3.7 ELISA Kit
 Potassium channel toxin alpha-KTx 3.7 Recombinant
 Potassium channel toxin alpha-KTx 3.7 Antibody
Also known as Potassium channel toxin alpha-KTx 3.7 (OsK-1) (OsK1).
Blocks voltage-gated potassium channels Kv1.1/KCNA1 (IC50=0.6nM), Kv1.2/KCNA2 (IC50=5.4nM), Kv1.3/KCNA3 (IC50=0.014nM) potently,
>>>
and moderately block intermediate conductance calcium-activated potassium channels KCa3.1/KCNN4 (IC50=225nM). At high concentration (2 mM), is also active on Kv1.6/KCNA6 and Shaker IR.
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Potassium channel toxin alpha-KTx 3.8

 Potassium channel toxin alpha-KTx 3.8 ELISA Kit
 Potassium channel toxin alpha-KTx 3.8 Recombinant
 Potassium channel toxin alpha-KTx 3.8 Antibody
Also known as Potassium channel toxin alpha-KTx 3.8 (Charybdotoxin-like peptide Bs 6) (Bs6).
Potassium channel inhibitor.
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Potassium channel toxin alpha-KTx 3.9

 Potassium channel toxin alpha-KTx 3.9 ELISA Kit
 Potassium channel toxin alpha-KTx 3.9 Recombinant
 Potassium channel toxin alpha-KTx 3.9 Antibody
Also known as Potassium channel toxin alpha-KTx 3.9 (Kaliotoxin-3) (KTX-3).
Binds and inhibits potassium channels. Intracerebroventricular injection into mice induces paralyzing symptoms followed by death. Its binding affinity to rat brain synaptosomes is 5-fold lower than this of KTX 1.
 KTX3 ELISA Kit
 KTX3 Recombinant
 KTX3 Antibody
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Potassium channel toxin alpha-KTx 31.1

 Potassium channel toxin alpha-KTx 31.1 ELISA Kit
 Potassium channel toxin alpha-KTx 31.1 Recombinant
 Potassium channel toxin alpha-KTx 31.1 Antibody
Also known as Potassium channel toxin alpha-KTx 31.1 (Kbot55).
Voltage-gated potassium channel inhibitor. 1 µM of the native toxin inhibits rat Kv1.2/KCNA2 (100% inhibition), and drosophila Shaker
>>>
IR/Sh (100%), human Kv1.3/KCNA3 (83%), rat Kv1.1/KCNA1 (32%) and rat Kv1.6/KCNA6 (21%).
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Potassium channel toxin alpha-KTx 4.1

 Potassium channel toxin alpha-KTx 4.1 ELISA Kit
 Potassium channel toxin alpha-KTx 4.1 Recombinant
 Potassium channel toxin alpha-KTx 4.1 Antibody
Also known as Potassium channel toxin alpha-KTx 4.1 (TSK4) (Tityustoxin K-alpha) (TsTX-K-alpha) (TyKalpha) (Toxin II-9) (Ts7).
Potently blocks Kv1.1/KCNA1 (85%), Kv1.2/KCNA2 (91%), Kv1.3/KCNA3 (89%
>>>
), Kv1.6/KCNA6 (94%), and Shaker (97%).
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Potassium channel toxin alpha-KTx 4.2

 Potassium channel toxin alpha-KTx 4.2 ELISA Kit
 Potassium channel toxin alpha-KTx 4.2 Recombinant
 Potassium channel toxin alpha-KTx 4.2 Antibody
Also known as Potassium channel toxin alpha-KTx 4.2 (Neurotoxin Ts-kappa) (TsK) (TsKappa) (Ts9).
Blocker for small-conductance calcium-activated potassium channels (SK / KCNN) (PubMed:9365990) and
>>>
ERG1/Kv11.1/KCNH2 potassium channels (PubMed:18687312).
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Potassium channel toxin alpha-KTx 4.3

 Potassium channel toxin alpha-KTx 4.3 ELISA Kit
 Potassium channel toxin alpha-KTx 4.3 Recombinant
 Potassium channel toxin alpha-KTx 4.3 Antibody
Also known as Potassium channel toxin alpha-KTx 4.3 (Toxin TdK1).
Blocks reversibly Shaker B potassium-channels.
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Potassium channel toxin alpha-KTx 4.4

 Potassium channel toxin alpha-KTx 4.4 ELISA Kit
 Potassium channel toxin alpha-KTx 4.4 Recombinant
 Potassium channel toxin alpha-KTx 4.4 Antibody
Also known as Potassium channel toxin alpha-KTx 4.4 (Toxin Tc30) (Toxin To30).
Reversible blocker of both Shaker B potassium channels (high affinity), and Kv1.3/KCNA3 potassium channels of human T
>>>
lymphocytes (low affinity).
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Potassium channel toxin alpha-KTx 4.5

 Potassium channel toxin alpha-KTx 4.5 ELISA Kit
 Potassium channel toxin alpha-KTx 4.5 Recombinant
 Potassium channel toxin alpha-KTx 4.5 Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 4.6

 Potassium channel toxin alpha-KTx 4.6 ELISA Kit
 Potassium channel toxin alpha-KTx 4.6 Recombinant
 Potassium channel toxin alpha-KTx 4.6 Antibody
Also known as Potassium channel toxin alpha-KTx 4.6 (Tst26).
Blocks potassium channels Kv1.2/KCNA2 and Kv1.3/KCNA3 with high affinity (K(d)=1.9 nM and 10.7 nM, respectively). The voltage-dependent
>>>
steady-state parameters of potassium channel gating are unaffected by the toxin in both channels, but due to the fast association and dissociation kinetics the toxin slows the rate of inactivation of Kv1.3/KCNA3 channels.
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Potassium channel toxin alpha-KTx 5.1

 Potassium channel toxin alpha-KTx 5.1 ELISA Kit
 Potassium channel toxin alpha-KTx 5.1 Recombinant
 Potassium channel toxin alpha-KTx 5.1 Antibody
Also known as Potassium channel toxin alpha-KTx 5.1 (Leiurotoxin I) (LeTx I) (Leiurotoxin-1) (Scyllatoxin) (ScyTx).
Blocker for the small conductance calcium-activated potassium channels (SK-Ca); a
>>>
lso known as apamine-sensitive potassium channel.
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Potassium channel toxin alpha-KTx 5.2

 Potassium channel toxin alpha-KTx 5.2 ELISA Kit
 Potassium channel toxin alpha-KTx 5.2 Recombinant
 Potassium channel toxin alpha-KTx 5.2 Antibody
Also known as Potassium channel toxin alpha-KTx 5.2 (AmP05) (Leiurotoxin I-like toxin P05).
Blocker for the small conductance calcium-activated potassium channels (SK-Ca); also known as apamine-sen
>>>
sitive potassium channel.
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Potassium channel toxin alpha-KTx 5.3

 Potassium channel toxin alpha-KTx 5.3 ELISA Kit
 Potassium channel toxin alpha-KTx 5.3 Recombinant
 Potassium channel toxin alpha-KTx 5.3 Antibody
Also known as Potassium channel toxin alpha-KTx 5.3 (Neurotoxin BmP05) (Potassium ion channel blocker P05).
Blocks small conductance calcium-activated potassium channels (KCNN, SK).
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Potassium channel toxin alpha-KTx 5.4

 Potassium channel toxin alpha-KTx 5.4 ELISA Kit
 Potassium channel toxin alpha-KTx 5.4 Recombinant
 Potassium channel toxin alpha-KTx 5.4 Antibody
Also known as Potassium channel toxin alpha-KTx 5.4 (Tamapin).
Blocks small conductance calcium-activated potassium channels in pyramidal neurons of the hippocampus. Displays a unique, remarkable s
>>>
electivity for SK2/KCNN2 versus SK1/KCNN1 and SK3/KCNN3 channels.
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Potassium channel toxin alpha-KTx 5.5

 Potassium channel toxin alpha-KTx 5.5 ELISA Kit
 Potassium channel toxin alpha-KTx 5.5 Recombinant
 Potassium channel toxin alpha-KTx 5.5 Antibody
Also known as Potassium channel toxin alpha-KTx 5.5 (Tamapin-2).
Blocks small conductance calcium-activated potassium channels.
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Potassium channel toxin alpha-KTx 6 hetlaxin

 Potassium channel toxin alpha-KTx 6 hetlaxin ELISA Kit
 Potassium channel toxin alpha-KTx 6 hetlaxin Recombinant
 Potassium channel toxin alpha-KTx 6 hetlaxin Antibody
Binds to voltage-gated potassium channels Kv1.3/KCNA3 (IC50=0.48 µM) and Kv1.1/KCNA1 (IC50=6.7 µM) and inhibits channel activity.
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Potassium channel toxin alpha-KTx 6 OcyKTx4

 Potassium channel toxin alpha-KTx 6 OcyKTx4 ELISA Kit
 Potassium channel toxin alpha-KTx 6 OcyKTx4 Recombinant
 Potassium channel toxin alpha-KTx 6 OcyKTx4 Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6 OcyKTx5

 Potassium channel toxin alpha-KTx 6 OcyKTx5 ELISA Kit
 Potassium channel toxin alpha-KTx 6 OcyKTx5 Recombinant
 Potassium channel toxin alpha-KTx 6 OcyKTx5 Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.1

 Potassium channel toxin alpha-KTx 6.1 ELISA Kit
 Potassium channel toxin alpha-KTx 6.1 Recombinant
 Potassium channel toxin alpha-KTx 6.1 Antibody
Also known as Potassium channel toxin alpha-KTx 6.1 (PiTX-K-gamma) (Potassium channel-blocking toxin 1) (Pi-1) (Pi1).
Potently and reversibly inhibits the insect voltage-gated Shaker (Sh) potassium
>>>
channel (isoform alpha (B)), the mammalian voltage-gated potassium channels Kv1.2/KCNA2. Its effect on Kv1.3/KCNA3 is controversial, since this channel is voltage-independently inhibited in PubMed:9464266, but is not affected in PubMed:10931199. Furthermore, this toxin competes with apamin (a small conductance calcium-activated potassium channel inhibitor) for binding onto rat brain synaptosomes.
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Potassium channel toxin alpha-KTx 6.10

 Potassium channel toxin alpha-KTx 6.10 ELISA Kit
 Potassium channel toxin alpha-KTx 6.10 Recombinant
 Potassium channel toxin alpha-KTx 6.10 Antibody
Also known as Potassium channel toxin alpha-KTx 6.10 (OcKTx5).
Blocker of voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.11

 Potassium channel toxin alpha-KTx 6.11 ELISA Kit
 Potassium channel toxin alpha-KTx 6.11 Recombinant
 Potassium channel toxin alpha-KTx 6.11 Antibody
Also known as Potassium channel toxin alpha-KTx 6.11 (Male-specific potassium channel inhibitor IsTX).
Blocks voltage-gated potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3. Causes paralysis to crick
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ets.
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Potassium channel toxin alpha-KTx 6.12

 Potassium channel toxin alpha-KTx 6.12 ELISA Kit
 Potassium channel toxin alpha-KTx 6.12 Recombinant
 Potassium channel toxin alpha-KTx 6.12 Antibody
Also known as Potassium channel toxin alpha-KTx 6.12 (Anuroctoxin).
High affinity blocker of Kv1.3/KCNA3 channels of human T cells. Blocks Kv1.2/KCNA2 with an order of magnitude smaller than for Kv
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1.3/KCNA3.
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Potassium channel toxin alpha-KTx 6.13

 Potassium channel toxin alpha-KTx 6.13 ELISA Kit
 Potassium channel toxin alpha-KTx 6.13 Recombinant
 Potassium channel toxin alpha-KTx 6.13 Antibody
Also known as Potassium channel toxin alpha-KTx 6.13 (Spinoxin).
Antagonist of Kv1/KCNA potassium channels.
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Potassium channel toxin alpha-KTx 6.14

 Potassium channel toxin alpha-KTx 6.14 ELISA Kit
 Potassium channel toxin alpha-KTx 6.14 Recombinant
 Potassium channel toxin alpha-KTx 6.14 Antibody
Also known as Potassium channel toxin alpha-KTx 6.14 (HgeTx1).
Blocks Shaker B channels expressed in Sf9 cells, with a dissociation constant of 52 nM.
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Potassium channel toxin alpha-KTx 6.15

 Potassium channel toxin alpha-KTx 6.15 ELISA Kit
 Potassium channel toxin alpha-KTx 6.15 Recombinant
 Potassium channel toxin alpha-KTx 6.15 Antibody
Also known as Potassium channel toxin alpha-KTx 6.15 (Hemitoxin).
Blocks rat voltage-gated potassium channels Kv1.1/KCNA1, Kv1.2/KCNA2 and Kv1.3/KCNA3 expressed in Xenopus oocytes with IC50 values
>>>
of 13 nM, 16 nM and 2 nM respectively.
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Potassium channel toxin alpha-KTx 6.16

 Potassium channel toxin alpha-KTx 6.16 ELISA Kit
 Potassium channel toxin alpha-KTx 6.16 Recombinant
 Potassium channel toxin alpha-KTx 6.16 Antibody
Also known as Potassium channel toxin alpha-KTx 6.16 (OcyC12).
Inhibits voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.17

 Potassium channel toxin alpha-KTx 6.17 ELISA Kit
 Potassium channel toxin alpha-KTx 6.17 Recombinant
 Potassium channel toxin alpha-KTx 6.17 Antibody
Also known as Potassium channel toxin alpha-KTx 6.17 (Toxin OcyKTx2).
This toxin reversibly blocks Shaker B potassium-channels (expressed in insect Sf9 cells) with a Kd of 96.6 nM, and presents an
>>>
even better affinity toward hKv1.3 (KCNA3), blocking it with a Kd of 17.7 nM.
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Potassium channel toxin alpha-KTx 6.2

 Potassium channel toxin alpha-KTx 6.2 ELISA Kit
 Potassium channel toxin alpha-KTx 6.2 Recombinant
 Potassium channel toxin alpha-KTx 6.2 Antibody
Also known as Potassium channel toxin alpha-KTx 6.2 (Maurotoxin) (MTX).
Blocks voltage-gated potassium channels (Shaker B, and Kv1.2/KCNA2 (IC50=0.8 nM)) and is also active on Kv1.1/KCNA1 (IC50=45
>>>
nM) and Kv1.3/KCNA3 (IC50=180 nM). Also inhibits apamin-sensitive small conductance calcium-activated potassium (SK/KCNN) channels, and inhibits intermediate conductance calcium-activated potassium KCa3.1/KCNN4 channels (IC50=1 nM).
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Potassium channel toxin alpha-KTx 6.21

 Potassium channel toxin alpha-KTx 6.21 ELISA Kit
 Potassium channel toxin alpha-KTx 6.21 Recombinant
 Potassium channel toxin alpha-KTx 6.21 Antibody
Also known as Potassium channel toxin alpha-KTx 6.21 (Urotoxin).
Blocker of voltage-gated potassium channels. Has highest activity on human voltage-gated potassium channel Kv1.2/KCNA2 channels, wit
>>>
h an IC50 of 160 pM, whereas its affinity for other channels tested was in the nanomolar range (hKv1.1/KCNA1, IC50=253 nM; hKv1.3/KCNA3, IC50=91 nM; and hKCa3.1/KCNN4, IC50=70 nM).
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Potassium channel toxin alpha-KTx 6.3

 Potassium channel toxin alpha-KTx 6.3 ELISA Kit
 Potassium channel toxin alpha-KTx 6.3 Recombinant
 Potassium channel toxin alpha-KTx 6.3 Antibody
Also known as Potassium channel toxin alpha-KTx 6.3 (Neurotoxin HsTX1).
Potently blocks voltage-gated potassium channels Kv1.1/KCNA1 and Kv1.3/KCNA3. Mildly blocks intermediate (IK) conductance cal
>>>
cium-activated potassium channels (KCa3.1/KCNN4) and ERG1/Kv11.1/KCNH2.
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Potassium channel toxin alpha-KTx 6.4

 Potassium channel toxin alpha-KTx 6.4 ELISA Kit
 Potassium channel toxin alpha-KTx 6.4 Recombinant
 Potassium channel toxin alpha-KTx 6.4 Antibody
Also known as Potassium channel toxin alpha-KTx 6.4 (Potassium channel-blocking toxin 4) (Pi-4) (Pi4).
Potently, completely and reversibly blocks voltage-gated potassium channel Kv1.2/KCNA2 and Sha
>>>
ker B (Sh). Also blocks small conductance (SK) calcium-activated potassium channel (KCNN).
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Potassium channel toxin alpha-KTx 6.5

 Potassium channel toxin alpha-KTx 6.5 ELISA Kit
 Potassium channel toxin alpha-KTx 6.5 Recombinant
 Potassium channel toxin alpha-KTx 6.5 Antibody
Also known as Potassium channel toxin alpha-KTx 6.5 (Pi-7) (Pi7) (Toxin-7).
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Potassium channel toxin alpha-KTx 6.6

 Potassium channel toxin alpha-KTx 6.6 ELISA Kit
 Potassium channel toxin alpha-KTx 6.6 Recombinant
 Potassium channel toxin alpha-KTx 6.6 Antibody
Also known as Potassium channel toxin alpha-KTx 6.6 (OcKTx1).
Blocker of voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.7

 Potassium channel toxin alpha-KTx 6.7 ELISA Kit
 Potassium channel toxin alpha-KTx 6.7 Recombinant
 Potassium channel toxin alpha-KTx 6.7 Antibody
Also known as Potassium channel toxin alpha-KTx 6.7 (OcKTx2).
Blocker of voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.8

 Potassium channel toxin alpha-KTx 6.8 ELISA Kit
 Potassium channel toxin alpha-KTx 6.8 Recombinant
 Potassium channel toxin alpha-KTx 6.8 Antibody
Also known as Potassium channel toxin alpha-KTx 6.8 (OcKTx3).
Blocker of voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 6.9

 Potassium channel toxin alpha-KTx 6.9 ELISA Kit
 Potassium channel toxin alpha-KTx 6.9 Recombinant
 Potassium channel toxin alpha-KTx 6.9 Antibody
Also known as Potassium channel toxin alpha-KTx 6.9 (OcKTx4).
Blocker of voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 7.1

 Potassium channel toxin alpha-KTx 7.1 ELISA Kit
 Potassium channel toxin alpha-KTx 7.1 Recombinant
 Potassium channel toxin alpha-KTx 7.1 Antibody
Also known as Potassium channel toxin alpha-KTx 7.1 (Pandinotoxin-alpha) (Potassium channel-blocking toxin 2) (Pi-2) (Pi2) (Toxin PiTX-K-alpha).
Potent inhibitor of the A-type voltage-gated potassium channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family).
 PTX-1 ELISA Kit
 PTX-1 Recombinant
 PTX-1 Antibody
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Potassium channel toxin alpha-KTx 7.2

 Potassium channel toxin alpha-KTx 7.2 ELISA Kit
 Potassium channel toxin alpha-KTx 7.2 Recombinant
 Potassium channel toxin alpha-KTx 7.2 Antibody
Also known as Potassium channel toxin alpha-KTx 7.2 (Pandinotoxin-beta) (Potassium channel-blocking toxin 3) (Pi-3) (Pi3) (Toxin PiTX-K-beta).
Potent inhibitor of the A-type voltage-gated potassium
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channels. Most potent inhibitor of Kv1.2/KCNA2 channels. Reversibly block the Shaker B potassium-channels (Kv1.1 sub-family), but with a lower affinity than PiTX-K alpha.
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Potassium channel toxin alpha-KTx 8.1

 Potassium channel toxin alpha-KTx 8.1 ELISA Kit
 Potassium channel toxin alpha-KTx 8.1 Recombinant
 Potassium channel toxin alpha-KTx 8.1 Antibody
Also known as Potassium channel toxin alpha-KTx 8.1 (AmP01) (Neurotoxin P01).
Blocker for the small conductance calcium-activated potassium channels (SK-Ca); also known as apamine-sensitive potassi
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um channel.
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Potassium channel toxin alpha-KTx 8.2

 Potassium channel toxin alpha-KTx 8.2 ELISA Kit
 Potassium channel toxin alpha-KTx 8.2 Recombinant
 Potassium channel toxin alpha-KTx 8.2 Antibody
Also known as Potassium channel toxin alpha-KTx 8.2 (Neurotoxin BmP01) (Potassium ion channel blocker P01).
Blocks small conductance calcium-activated potassium channels (KCNN, SK). Low toxicity by
>>>
intracerebroventricular injection into mice.
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Potassium channel toxin alpha-KTx 8.4

 Potassium channel toxin alpha-KTx 8.4 ELISA Kit
 Potassium channel toxin alpha-KTx 8.4 Recombinant
 Potassium channel toxin alpha-KTx 8.4 Antibody
Also known as Potassium channel toxin alpha-KTx 8.4 (Leiuropeptide III) (LpIII) (Leiuropeptide-3).
Inhibits voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 8.5

 Potassium channel toxin alpha-KTx 8.5 ELISA Kit
 Potassium channel toxin alpha-KTx 8.5 Recombinant
 Potassium channel toxin alpha-KTx 8.5 Antibody
Also known as Potassium channel toxin alpha-KTx 8.5 (OdK1).
Selectively inhibits voltage-gated potassium channels Kv1.2/KCNA2 with an IC50 of 183 nM.
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Potassium channel toxin alpha-KTx 8.6

 Potassium channel toxin alpha-KTx 8.6 ELISA Kit
 Potassium channel toxin alpha-KTx 8.6 Recombinant
 Potassium channel toxin alpha-KTx 8.6 Antibody
Also known as Potassium channel toxin alpha-KTx 8.6 (Toxin MeuKTx-1).
Inhibits Kv1.1/KCNA1, Kv3/KCNC and Shaker potassium channels.
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Potassium channel toxin alpha-KTx 8.7

 Potassium channel toxin alpha-KTx 8.7 ELISA Kit
 Potassium channel toxin alpha-KTx 8.7 Recombinant
 Potassium channel toxin alpha-KTx 8.7 Antibody
Also known as Potassium channel toxin alpha-KTx 8.7 (Toxin MeKTx1-2).
Inhibits voltage-gated potassium channel rKv1.1/KCNA1 at nanomolar ranges (IC50=8.5 +-1.2 nM, 100% inhibition at 50 nM of toxin
>>>
).
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Potassium channel toxin alpha-KTx 9.1

 Potassium channel toxin alpha-KTx 9.1 ELISA Kit
 Potassium channel toxin alpha-KTx 9.1 Recombinant
 Potassium channel toxin alpha-KTx 9.1 Antibody
Also known as Potassium channel toxin alpha-KTx 9.1 (BmKK6) (Neurotoxin BmP02) (Potassium ion channel blocker P02) (Toxin Kk6).
Blocks small conductance calcium-activated potassium channels (KCNN,
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SK). Weakly inhibits the Kv7.1/KCNQ1 channel (10 µM of the toxin inhibits currents by 23.3%). Low toxicity by intracerebroventricular injection into mice.
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Potassium channel toxin alpha-KTx 9.10

 Potassium channel toxin alpha-KTx 9.10 ELISA Kit
 Potassium channel toxin alpha-KTx 9.10 Recombinant
 Potassium channel toxin alpha-KTx 9.10 Antibody
Also known as Potassium channel toxin alpha-KTx 9.10 (Toxin MeuKTx-5).
Blocks Shaker potassium channels.
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Potassium channel toxin alpha-KTx 9.11

 Potassium channel toxin alpha-KTx 9.11 ELISA Kit
 Potassium channel toxin alpha-KTx 9.11 Recombinant
 Potassium channel toxin alpha-KTx 9.11 Antibody
Also known as Potassium channel toxin alpha-KTx 9.11 (Toxin MegKTx2).
May play a role in blocking voltage-gated potassium channels Kv1.2/KCNA2, Kv1.3/KCNA3 and Kv1.6/KCNA6 to a lesser extent.
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Potassium channel toxin alpha-KTx 9.2

 Potassium channel toxin alpha-KTx 9.2 ELISA Kit
 Potassium channel toxin alpha-KTx 9.2 Recombinant
 Potassium channel toxin alpha-KTx 9.2 Antibody
Also known as Potassium channel toxin alpha-KTx 9.2 (Neurotoxin BmP03) (Potassium ion channel blocker P03).
Blocks small conductance calcium-activated potassium channels (KCNN, SK). Low toxicity by
>>>
intracerebroventricular injection into mice.
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Potassium channel toxin alpha-KTx 9.3

 Potassium channel toxin alpha-KTx 9.3 ELISA Kit
 Potassium channel toxin alpha-KTx 9.3 Recombinant
 Potassium channel toxin alpha-KTx 9.3 Antibody
Also known as Potassium channel toxin alpha-KTx 9.3 (Leiuropeptide I) (LpI) (Leiuropeptide-1).
Inhibits voltage-gated potassium channels.
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Potassium channel toxin alpha-KTx 9.4

 Potassium channel toxin alpha-KTx 9.4 ELISA Kit
 Potassium channel toxin alpha-KTx 9.4 Recombinant
 Potassium channel toxin alpha-KTx 9.4 Antibody
Also known as Potassium channel toxin alpha-KTx 9.4 (Bt BTK-2) (Toxin BTK-2).
Blocker of human potassium channel Kv1.1/KCNA1.
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Potassium channel toxin alpha-KTx 9.5

 Potassium channel toxin alpha-KTx 9.5 ELISA Kit
 Potassium channel toxin alpha-KTx 9.5 Recombinant
 Potassium channel toxin alpha-KTx 9.5 Antibody
Also known as Potassium channel toxin alpha-KTx 9.5 (Neurotoxin Kbot1).
Binds and inhibits voltage-gated potassium channels, with varying affinities for Kv1.2/KCNA2 > Kv1.3/KCNA3 > Kv1.1/KCNA1. Als
>>>
o inhibits calcium-activated potassium channels (KCa/KCNN).
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Potassium channel toxin alpha-KTx 9.6

 Potassium channel toxin alpha-KTx 9.6 ELISA Kit
 Potassium channel toxin alpha-KTx 9.6 Recombinant
 Potassium channel toxin alpha-KTx 9.6 Antibody
Also known as Potassium channel toxin alpha-KTx 9.6 (BjTx-1) (Neurotoxin Tx-1).
Calcium channel activator. Rapidly and reversibly activates ryanodine receptor 1 (RYR1).
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Potassium channel toxin alpha-KTx 9.7

 Potassium channel toxin alpha-KTx 9.7 ELISA Kit
 Potassium channel toxin alpha-KTx 9.7 Recombinant
 Potassium channel toxin alpha-KTx 9.7 Antibody
Also known as Potassium channel toxin alpha-KTx 9.7 (BjTx-2) (Neurotoxin Tx-2).
Calcium channel activator. Rapidly and reversibly activates ryanodine receptor 1 (RYR1).
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Potassium channel toxin alpha-KTx 9.8

 Potassium channel toxin alpha-KTx 9.8 ELISA Kit
 Potassium channel toxin alpha-KTx 9.8 Recombinant
 Potassium channel toxin alpha-KTx 9.8 Antibody
Also known as Potassium channel toxin alpha-KTx 9.8 (Toxin Tx784).
Potassium channel inhibitor.
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Potassium channel toxin alpha-KTx 9.9

 Potassium channel toxin alpha-KTx 9.9 ELISA Kit
 Potassium channel toxin alpha-KTx 9.9 Recombinant
 Potassium channel toxin alpha-KTx 9.9 Antibody
Also known as Potassium channel toxin alpha-KTx 9.9 (Toxin Tx549).
Potassium channel inhibitor.
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Potassium channel toxin alpha-KTx BmKcug1a

 Potassium channel toxin alpha-KTx BmKcug1a ELISA Kit
 Potassium channel toxin alpha-KTx BmKcug1a Recombinant
 Potassium channel toxin alpha-KTx BmKcug1a Antibody
Also known as Potassium channel toxin alpha-KTx BmKcug1a (Kcug1a).
Potent blocker of both large-conductance calcium-activated potassium channels (KCa1.1/KCNMA1) and voltage-gated potassium channels
>>>
(Kv1.3/KCNA3 and ERG1/Kv11.1/KCNH2).
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Potassium channel toxin alpha-KTx Ctri9577

 Potassium channel toxin alpha-KTx Ctri9577 ELISA Kit
 Potassium channel toxin alpha-KTx Ctri9577 Recombinant
 Potassium channel toxin alpha-KTx Ctri9577 Antibody
Recombinant peptide selectively inhibits mKv1.3/KCNA3 channel current with an IC50 of 0.49 nM.
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Potassium channel toxin alpha-KTx J123

 Potassium channel toxin alpha-KTx J123 ELISA Kit
 Potassium channel toxin alpha-KTx J123 Recombinant
 Potassium channel toxin alpha-KTx J123 Antibody
This recombinant toxin inhibits the mammalian voltage-gated potassium channels Kv1.3/KCNA3 and Kv1.2/KCNA2 in vitro with IC50 of 0.79 nM and 26.4 nM, respectively.
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Potassium channel toxin alpha-KTx Tx308

 Potassium channel toxin alpha-KTx Tx308 ELISA Kit
 Potassium channel toxin alpha-KTx Tx308 Recombinant
 Potassium channel toxin alpha-KTx Tx308 Antibody
May block potassium channels.
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Potassium channel toxin alpha-KTx Tx773

 Potassium channel toxin alpha-KTx Tx773 ELISA Kit
 Potassium channel toxin alpha-KTx Tx773 Recombinant
 Potassium channel toxin alpha-KTx Tx773 Antibody
May block potassium channels.
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Potassium channel toxin alpha-KTx Tx790

 Potassium channel toxin alpha-KTx Tx790 ELISA Kit
 Potassium channel toxin alpha-KTx Tx790 Recombinant
 Potassium channel toxin alpha-KTx Tx790 Antibody
May block potassium channels.
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Potassium channel toxin alpha-KTx6 OcyKTx1

 Potassium channel toxin alpha-KTx6 OcyKTx1 ELISA Kit
 Potassium channel toxin alpha-KTx6 OcyKTx1 Recombinant
 Potassium channel toxin alpha-KTx6 OcyKTx1 Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin beta-Ktx 2

 Potassium channel toxin beta-Ktx 2 ELISA Kit
 Potassium channel toxin beta-Ktx 2 Recombinant
 Potassium channel toxin beta-Ktx 2 Antibody
Also known as Potassium channel toxin beta-Ktx 2 (Ts19).
Potassium channel toxin beta-Ktx 2-1: may function as a voltage-gated potassium channel blocker and may have cytolytic activity (Ref. 2).
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Potassium channel toxin BmTXK-beta

 Potassium channel toxin BmTXK-beta ELISA Kit
 Potassium channel toxin BmTXK-beta Recombinant
 Potassium channel toxin BmTXK-beta Antibody
Also known as Potassium channel toxin BmTXK-beta (BmKLK) (Potassium channel toxin beta-KTx 3) (Toxin BmTX K-beta) (BmTXKbeta).
This recombinant peptide reversibly and dose-dependently inhibits the
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transient outward potassium current (I(To)) of rabbit atrial myocyte and prolongs the action potential duration of rabbit atrial myocyte without affecting the action potential amplitude. Thus, the voltage-gated potassium channels Kv4.1/KCND1, Kv4.2/KCND2, Kv4.3/KCND3 may be the target of this toxin.
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Potassium channel toxin BmTXK-beta-2

 Potassium channel toxin BmTXK-beta-2 ELISA Kit
 Potassium channel toxin BmTXK-beta-2 Recombinant
 Potassium channel toxin BmTXK-beta-2 Antibody
Also known as Potassium channel toxin BmTXK-beta-2 (BmTX K beta2') (BmTXKbeta2) (Toxin BmTX K-beta2) (Potassium channel toxin beta-KTx 4).
Blocks voltage-gated potassium channels.
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Potassium channel toxin BuTXK-beta

 Potassium channel toxin BuTXK-beta ELISA Kit
 Potassium channel toxin BuTXK-beta Recombinant
 Potassium channel toxin BuTXK-beta Antibody
Also known as Potassium channel toxin BuTXK-beta (BuTXKbeta) (Potassium channel toxin Tx690).
Blocks voltage-gated potassium channels.
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Potassium channel toxin gamma-KTx 1.1

 Potassium channel toxin gamma-KTx 1.1 ELISA Kit
 Potassium channel toxin gamma-KTx 1.1 Recombinant
 Potassium channel toxin gamma-KTx 1.1 Antibody
Also known as Potassium channel toxin gamma-KTx 1.1 (Ergtoxin) (CnErg1) (CnErgTx1) (ErgTx) (ErgTx1).
Blocks human and rat Kv11.1/KCNH2/ERG1 and Kv11.3/KCNH7/ERG3, as well as rat (but not human) Kv1
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1.2/KCNH6/ERG2 (PubMed:11755529, PubMed:11864985, PubMed:16497878, PubMed:17369411, PubMed:20600425) by binding to channel outer vestibule (S5P domain) with a 1:1 stoichiometry (PubMed:11755529, PubMed:11864985, PubMed:17369411, PubMed:20600425). Inhibition data are the following: hERG1 (reversible, IC50~7 nM) (PubMed:11755529, PubMed:11864985, PubMed:16497878, PubMed:17369411, PubMed:20600425), rERG1 (reversible, Kd=6.8 nM) (PubMed:16497878), rERG2 (irreversible, Kd=2.8 nM) (PubMed:16497878), hERG3 (irreversible, Kd=4.05 nM) (PubMed:16497878) and rERG3 (reversible, Kd=38.1 nM) (PubMed:16497878) potassium channels. The toxin potency is not affected by elevating potassium ion concentration from 2 to 98 mM (PubMed:11864985). This toxin only blocks channels in a closed state (PubMed:12860380). At high toxin concentrations, block of Kv11.1/KCNH2/ERG1 macroscopic current is incomplete (93.5%). This suggests a kinetic mechanism model with two different states of toxin-channel binding (T+C=TC*=TC; in the TC* state, the toxin binds the channel but does not occlude the pore, whereas in the TC state the toxin binds and occludes the pore). In this model, incomplete block is explained by the relatively fast dissociation rate from the blocked channel conformation (TC) relative to the rate of conversion of the toxin-channel encounter complex (TC*) to the blocked channel conformation (TC) (PubMed:17369411).
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Potassium channel toxin gamma-KTx 1.2

 Potassium channel toxin gamma-KTx 1.2 ELISA Kit
 Potassium channel toxin gamma-KTx 1.2 Recombinant
 Potassium channel toxin gamma-KTx 1.2 Antibody
Also known as Potassium channel toxin gamma-KTx 1.2 (CeErgTx1) (CeErg1) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 1.3

 Potassium channel toxin gamma-KTx 1.3 ELISA Kit
 Potassium channel toxin gamma-KTx 1.3 Recombinant
 Potassium channel toxin gamma-KTx 1.3 Antibody
Also known as Potassium channel toxin gamma-KTx 1.3 (CgErgTx1) (CgErg1) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 1.4

 Potassium channel toxin gamma-KTx 1.4 ELISA Kit
 Potassium channel toxin gamma-KTx 1.4 Recombinant
 Potassium channel toxin gamma-KTx 1.4 Antibody
Also known as Potassium channel toxin gamma-KTx 1.4 (CsErgTx1) (CsErg1) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 1.5

 Potassium channel toxin gamma-KTx 1.5 ELISA Kit
 Potassium channel toxin gamma-KTx 1.5 Recombinant
 Potassium channel toxin gamma-KTx 1.5 Antibody
Also known as Potassium channel toxin gamma-KTx 1.5 (CllErgTx1) (CllErg1) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 1.6

 Potassium channel toxin gamma-KTx 1.6 ELISA Kit
 Potassium channel toxin gamma-KTx 1.6 Recombinant
 Potassium channel toxin gamma-KTx 1.6 Antibody
Also known as Potassium channel toxin gamma-KTx 1.6 (CexErgTx1) (CexErg1) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 1.7

 Potassium channel toxin gamma-KTx 1.7 ELISA Kit
 Potassium channel toxin gamma-KTx 1.7 Recombinant
 Potassium channel toxin gamma-KTx 1.7 Antibody
Also known as Potassium channel toxin gamma-KTx 1.7 (CeErgTx4) (CeErg4).
Blocks in a reversible manner human and rat Kv11.1/KCNH2/ERG1 potassium channels. Also completely and irreversibly blocks ra
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t Kv11.2/KCNH6/ERG2 and human Kv11.3/KCNH7/ERG3 channels.
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Potassium channel toxin gamma-KTx 1.8

 Potassium channel toxin gamma-KTx 1.8 ELISA Kit
 Potassium channel toxin gamma-KTx 1.8 Recombinant
 Potassium channel toxin gamma-KTx 1.8 Antibody
Also known as Potassium channel toxin gamma-KTx 1.8 (CeErgTx5) (CeErg5).
Blocks in a reversible manner human and rat Kv11.1/KCNH2/ERG1 potassium channels. Also completely and irreversibly blocks ra
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t Kv11.2/KCNH6/ERG2 and human Kv11.3/KCNH7/ERG3 channels.
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Potassium channel toxin gamma-KTx 2.1

 Potassium channel toxin gamma-KTx 2.1 ELISA Kit
 Potassium channel toxin gamma-KTx 2.1 Recombinant
 Potassium channel toxin gamma-KTx 2.1 Antibody
Also known as Potassium channel toxin gamma-KTx 2.1 (Neurotoxin BeKm-1) (BeKm1).
Blocks human and/or rat Kv11.1/KCNH2/ERG1, Kv11.2/KCNH6/ERG2 and Kv11.3/KCNH7/ERG3 by binding to channel outer vesti
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bule (S5P domain) with a 1:1 stoichiometry. Inhibition data are the following: hERG1 (reversible, Kd=7.7 nM (PubMed:16497878), IC50=3.3 nM (PubMed:11136720), IC50=11.9 nM (PubMed:21205913)), rERG1 (reversible, Kd=19 nM) (PubMed:16497878), hERG2 (reversible, Kd=77 nM) (PubMed:16497878), rERG2 (irreversible, Kd=4.2 nM) (PubMed:16497878), hERG3 (reversible, Kd=11.5 nM) (PubMed:16497878) and rERG3 (reversible, Kd=747 nM) (PubMed:16497878) potassium channels. Has also a minimal effect on rat ELK1/KCNH4 potassium channels (9% inhibition at 100 nM (PubMed:15137031)). Both this toxin and CnErgTx1 (AC Q86QT3) share mechanism of action and have overlapping binding sites on ERG1 (PubMed:12719233). The potency of these two toxins is not affected by elevating potassium ion concentration from 2 to 98 mM (PubMed:12719233). In addition, at high toxin concentrations, block of ERG1 macroscopic currents by these two toxins is incomplete (88%) (PubMed:12719233). The blockade by this toxin is preferentially closed channel state-dependent, with a component of open, but not inactive state-dependent blockade (PubMed:12860380). This toxin produces a concentration-dependent prolongation of QTc in the isolated rabbit heart (16.3% at 100 nM) (PubMed:21205913).
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Potassium channel toxin gamma-KTx 2.2

 Potassium channel toxin gamma-KTx 2.2 ELISA Kit
 Potassium channel toxin gamma-KTx 2.2 Recombinant
 Potassium channel toxin gamma-KTx 2.2 Antibody
Also known as Potassium channel toxin gamma-KTx 2.2 (BmKK7) (BmKKx2).
Blocks human and/or rat Kv11.1/KCNH2/ERG1, Kv11.2/KCNH6/ERG2 and Kv11.3/KCNH7/ERG3 by binding to channel outer vestibule (S5P d
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omain) with a 1:1 stoichiometry. Has also a minimal effect on rat ELK1/KCNH4 potassium channels.
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Potassium channel toxin gamma-KTx 3.1

 Potassium channel toxin gamma-KTx 3.1 ELISA Kit
 Potassium channel toxin gamma-KTx 3.1 Recombinant
 Potassium channel toxin gamma-KTx 3.1 Antibody
Also known as Potassium channel toxin gamma-KTx 3.1 (CnErgTx2) (CnErg2) (Ergtoxin-2) (ErgTx2) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels (tested in MMQ lactotroph cells that contai
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n the three ERG channels: rKv11.1/KCNH2/ERG1, rKv11.2/KCNH6/ERG2 and rKv11.3/KCNH7/ERG3). This toxin can be used to distinguish slow deactivating components (ERGS) from fast deactivating components (ERGF) currents, since it specifically blocks ERGS.
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Potassium channel toxin gamma-KTx 3.2

 Potassium channel toxin gamma-KTx 3.2 ELISA Kit
 Potassium channel toxin gamma-KTx 3.2 Recombinant
 Potassium channel toxin gamma-KTx 3.2 Antibody
Also known as Potassium channel toxin gamma-KTx 3.2 (CeErgTx2) (CeErg2) (ErgTx2) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 3.3

 Potassium channel toxin gamma-KTx 3.3 ELISA Kit
 Potassium channel toxin gamma-KTx 3.3 Recombinant
 Potassium channel toxin gamma-KTx 3.3 Antibody
Also known as Potassium channel toxin gamma-KTx 3.3 (CsErgTx2) (CsErg2) (ErgTx2) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 3.4

 Potassium channel toxin gamma-KTx 3.4 ELISA Kit
 Potassium channel toxin gamma-KTx 3.4 Recombinant
 Potassium channel toxin gamma-KTx 3.4 Antibody
Also known as Potassium channel toxin gamma-KTx 3.4 (CgErgTx2) (CgErg2) (ErgTx2) (Ergtoxin-like protein).
Blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.1

 Potassium channel toxin gamma-KTx 4.1 ELISA Kit
 Potassium channel toxin gamma-KTx 4.1 Recombinant
 Potassium channel toxin gamma-KTx 4.1 Antibody
Also known as Potassium channel toxin gamma-KTx 4.1 (CllErgTx2) (CllErg2) (ErgTx2) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.10

 Potassium channel toxin gamma-KTx 4.10 ELISA Kit
 Potassium channel toxin gamma-KTx 4.10 Recombinant
 Potassium channel toxin gamma-KTx 4.10 Antibody
Also known as Potassium channel toxin gamma-KTx 4.10 (CsErgTx4) (CsErg4) (ErgTx4) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.11

 Potassium channel toxin gamma-KTx 4.11 ELISA Kit
 Potassium channel toxin gamma-KTx 4.11 Recombinant
 Potassium channel toxin gamma-KTx 4.11 Antibody
Also known as Potassium channel toxin gamma-KTx 4.11 (CnErgTx4) (CnErg4) (ErgTx4) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.12

 Potassium channel toxin gamma-KTx 4.12 ELISA Kit
 Potassium channel toxin gamma-KTx 4.12 Recombinant
 Potassium channel toxin gamma-KTx 4.12 Antibody
Also known as Potassium channel toxin gamma-KTx 4.12 (CsEKerg1).
Reversibly blocks Kv11/ERG potassium channels. Is less toxic than ergtoxin (AC Q86QT3).
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Potassium channel toxin gamma-KTx 4.13

 Potassium channel toxin gamma-KTx 4.13 ELISA Kit
 Potassium channel toxin gamma-KTx 4.13 Recombinant
 Potassium channel toxin gamma-KTx 4.13 Antibody
Also known as Potassium channel toxin gamma-KTx 4.13 (CnErgTx3) (CnErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.2

 Potassium channel toxin gamma-KTx 4.2 ELISA Kit
 Potassium channel toxin gamma-KTx 4.2 Recombinant
 Potassium channel toxin gamma-KTx 4.2 Antibody
Also known as Potassium channel toxin gamma-KTx 4.2 (CnErgTx5) (CnErg5) (ErgTx5) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.3

 Potassium channel toxin gamma-KTx 4.3 ELISA Kit
 Potassium channel toxin gamma-KTx 4.3 Recombinant
 Potassium channel toxin gamma-KTx 4.3 Antibody
Also known as Potassium channel toxin gamma-KTx 4.3 (CexErgTx2) (CexErg2) (ErgTx2) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.4

 Potassium channel toxin gamma-KTx 4.4 ELISA Kit
 Potassium channel toxin gamma-KTx 4.4 Recombinant
 Potassium channel toxin gamma-KTx 4.4 Antibody
Also known as Potassium channel toxin gamma-KTx 4.4 (CexErgTx3) (CexErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.5

 Potassium channel toxin gamma-KTx 4.5 ELISA Kit
 Potassium channel toxin gamma-KTx 4.5 Recombinant
 Potassium channel toxin gamma-KTx 4.5 Antibody
Also known as Potassium channel toxin gamma-KTx 4.5 (CexErgTx4) (CexErg4) (ErgTx4) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.6

 Potassium channel toxin gamma-KTx 4.6 ELISA Kit
 Potassium channel toxin gamma-KTx 4.6 Recombinant
 Potassium channel toxin gamma-KTx 4.6 Antibody
Also known as Potassium channel toxin gamma-KTx 4.6 (CllErgTx3) (CllErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.7

 Potassium channel toxin gamma-KTx 4.7 ELISA Kit
 Potassium channel toxin gamma-KTx 4.7 Recombinant
 Potassium channel toxin gamma-KTx 4.7 Antibody
Also known as Potassium channel toxin gamma-KTx 4.7 (CllErgTx4) (CllErg4) (ErgTx4) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.8

 Potassium channel toxin gamma-KTx 4.8 ELISA Kit
 Potassium channel toxin gamma-KTx 4.8 Recombinant
 Potassium channel toxin gamma-KTx 4.8 Antibody
Also known as Potassium channel toxin gamma-KTx 4.8 (CeErgTx3) (CeErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 4.9

 Potassium channel toxin gamma-KTx 4.9 ELISA Kit
 Potassium channel toxin gamma-KTx 4.9 Recombinant
 Potassium channel toxin gamma-KTx 4.9 Antibody
Also known as Potassium channel toxin gamma-KTx 4.9 (CsErgTx3) (CsErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 5.1

 Potassium channel toxin gamma-KTx 5.1 ELISA Kit
 Potassium channel toxin gamma-KTx 5.1 Recombinant
 Potassium channel toxin gamma-KTx 5.1 Antibody
Also known as Potassium channel toxin gamma-KTx 5.1 (CsErgTx5) (CsErg5) (ErgTx5) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin gamma-KTx 5.2

 Potassium channel toxin gamma-KTx 5.2 ELISA Kit
 Potassium channel toxin gamma-KTx 5.2 Recombinant
 Potassium channel toxin gamma-KTx 5.2 Antibody
Also known as Potassium channel toxin gamma-KTx 5.2 (CgErgTx3) (CgErg3) (ErgTx3) (Ergtoxin-like protein).
Reversibly blocks Kv11/ERG potassium channels.
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Potassium channel toxin Hge-beta-KTx

 Potassium channel toxin Hge-beta-KTx ELISA Kit
 Potassium channel toxin Hge-beta-KTx Recombinant
 Potassium channel toxin Hge-beta-KTx Antibody
Also known as Potassium channel toxin Hge-beta-KTx (HgebetaKTx).
The full peptide presents antibacterial and cytotoxic activities. The C-terminus (33-76aa) blocks potassium channels Kv1.1/KCNA1, Kv
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1.2/KCNA2, and Kv1.3/KCNA3.
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Potassium channel toxin ImKTx88

 Potassium channel toxin ImKTx88 ELISA Kit
 Potassium channel toxin ImKTx88 Recombinant
 Potassium channel toxin ImKTx88 Antibody
Recombinant toxin selectively inhibits Kv1.3/KCNA3 potassium channels with an IC50 of 91 pM.
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Potassium channel toxin kappa-KTx 1.1

 Potassium channel toxin kappa-KTx 1.1 ELISA Kit
 Potassium channel toxin kappa-KTx 1.1 Recombinant
 Potassium channel toxin kappa-KTx 1.1 Antibody
Also known as Potassium channel toxin kappa-KTx 1.1 (Kappa-hefutoxin-1) (Kappa-HfTx1).
Slows the activation kinetics of Kv1.3/KCNA3 currents, and blocks Kv1.3/KCNA3 and Kv1.2/KCNA2 potassium channe
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ls. This block is dose-dependent, voltage-independent, and reversible.
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Potassium channel toxin kappa-KTx 1.2

 Potassium channel toxin kappa-KTx 1.2 ELISA Kit
 Potassium channel toxin kappa-KTx 1.2 Recombinant
 Potassium channel toxin kappa-KTx 1.2 Antibody
Also known as Potassium channel toxin kappa-KTx 1.2 (Kappa-hefutoxin-2) (Kappa-HfTx2).
Slows the activation kinetics of Kv1.3/KCNA3 currents, and blocks Kv1.3/KCNA3 and Kv1.2/KCNA2 potassium channe
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ls. This block is dose-dependent, voltage-independent, and reversible ().
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Potassium channel toxin kappa-KTx 1.3

 Potassium channel toxin kappa-KTx 1.3 ELISA Kit
 Potassium channel toxin kappa-KTx 1.3 Recombinant
 Potassium channel toxin kappa-KTx 1.3 Antibody
Has no effect on potassium channels.
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Potassium channel toxin kappa-KTx 1.4

 Potassium channel toxin kappa-KTx 1.4 ELISA Kit
 Potassium channel toxin kappa-KTx 1.4 Recombinant
 Potassium channel toxin kappa-KTx 1.4 Antibody
Also known as Potassium channel toxin kappa-KTx 1.4 (HSP009C).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 2.2

 Potassium channel toxin kappa-KTx 2.2 ELISA Kit
 Potassium channel toxin kappa-KTx 2.2 Recombinant
 Potassium channel toxin kappa-KTx 2.2 Antibody
Also known as Potassium channel toxin kappa-KTx 2.2 (Toxin OmTx2).
OmTx1 decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 17% and Kv1.2/KCNA2 by 12% as well as hu
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man Kv1.3/KCNA3 by 24%.
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Potassium channel toxin kappa-KTx 2.3

 Potassium channel toxin kappa-KTx 2.3 ELISA Kit
 Potassium channel toxin kappa-KTx 2.3 Recombinant
 Potassium channel toxin kappa-KTx 2.3 Antibody
Also known as Potassium channel toxin kappa-KTx 2.3 (Toxin OmTx3).
Decreases the amplitude of the potassium current of the rat channels Kv1.1/KCNA1 by 33% and Kv1.2/KCNA2 by 8% as well as human Kv1
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.3/KCNA3 by 70%.
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Potassium channel toxin kappa-KTx 2.5

 Potassium channel toxin kappa-KTx 2.5 ELISA Kit
 Potassium channel toxin kappa-KTx 2.5 Recombinant
 Potassium channel toxin kappa-KTx 2.5 Antibody
Also known as Potassium channel toxin kappa-KTx 2.5 (OcyC8) (OcyKTx6).
Voltage-independently blocks potassium currents on human Kv1.1/KCNA1 (IC50=217 µM), and human Kv1.4/KCNA4 (IC50=71 µM) (expr
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essed in CHO cells).
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Potassium channel toxin kappa-KTx 2.6

 Potassium channel toxin kappa-KTx 2.6 ELISA Kit
 Potassium channel toxin kappa-KTx 2.6 Recombinant
 Potassium channel toxin kappa-KTx 2.6 Antibody
Also known as Potassium channel toxin kappa-KTx 2.6 (OcyC9).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 2.7

 Potassium channel toxin kappa-KTx 2.7 ELISA Kit
 Potassium channel toxin kappa-KTx 2.7 Recombinant
 Potassium channel toxin kappa-KTx 2.7 Antibody
Also known as Potassium channel toxin kappa-KTx 2.7 (HSP053C.1) (Toxin HeTx203) (Toxin kappa-KTx 2.6).
Weakly inhibits the Kv7.1/KCNQ1 channel (10 µM of the toxin inhibits currents by 17.8%).
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Potassium channel toxin kappa-KTx 2.8

 Potassium channel toxin kappa-KTx 2.8 ELISA Kit
 Potassium channel toxin kappa-KTx 2.8 Recombinant
 Potassium channel toxin kappa-KTx 2.8 Antibody
Also known as Potassium channel toxin kappa-KTx 2.8 (HSP053C.2) (Toxin HeTx204) (Toxin kappa-KTx 2.7).
Voltage-gated potassium channel inhibitor (Kv) that acts on Kv1.3/KCNA3 and Kv7.1/KCNQ1. 1 µM
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of the toxin inhibits Kv1.3/KCNA3 currents by 35.1%, whereas 10 µM of the toxin inhibits Kv7.1/KCNQ1 currents by 44.9%.
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Potassium channel toxin kappa-KTx 3.1

 Potassium channel toxin kappa-KTx 3.1 ELISA Kit
 Potassium channel toxin kappa-KTx 3.1 Recombinant
 Potassium channel toxin kappa-KTx 3.1 Antibody
Also known as Potassium channel toxin kappa-KTx 3.1 (HSP040C.1).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 3.2

 Potassium channel toxin kappa-KTx 3.2 ELISA Kit
 Potassium channel toxin kappa-KTx 3.2 Recombinant
 Potassium channel toxin kappa-KTx 3.2 Antibody
Also known as Potassium channel toxin kappa-KTx 3.2 (HSP040C.3).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 3.3

 Potassium channel toxin kappa-KTx 3.3 ELISA Kit
 Potassium channel toxin kappa-KTx 3.3 Recombinant
 Potassium channel toxin kappa-KTx 3.3 Antibody
Also known as Potassium channel toxin kappa-KTx 3.3 (HSP040C.4).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 3.4

 Potassium channel toxin kappa-KTx 3.4 ELISA Kit
 Potassium channel toxin kappa-KTx 3.4 Recombinant
 Potassium channel toxin kappa-KTx 3.4 Antibody
Also known as Potassium channel toxin kappa-KTx 3.4 (HSP040C.5).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 4.1

 Potassium channel toxin kappa-KTx 4.1 ELISA Kit
 Potassium channel toxin kappa-KTx 4.1 Recombinant
 Potassium channel toxin kappa-KTx 4.1 Antibody
Also known as Potassium channel toxin kappa-KTx 4.1 (HSP040C.2).
Potassium channel inhibitor (Kv).
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Potassium channel toxin kappa-KTx 5.1

 Potassium channel toxin kappa-KTx 5.1 ELISA Kit
 Potassium channel toxin kappa-KTx 5.1 Recombinant
 Potassium channel toxin kappa-KTx 5.1 Antibody
Also known as Potassium channel toxin kappa-KTx 5.1 (HelaTx1).
Blocker of potassium channels Kv1.1/KCNA1 (EC(50)=9.9 µM) and Kv1.6/KCNA6. Acts by binding to the pore and occluding it. Has a voltag
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e-dependent mode of action, which can be explained by a high content of basic residues causing repulsions at higher membrane voltages.
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Potassium channel toxin KTx1

 Potassium channel toxin KTx1 ELISA Kit
 Potassium channel toxin KTx1 Recombinant
 Potassium channel toxin KTx1 Antibody
Also known as Potassium channel toxin KTx1 (ImKTx1).
This recombinant peptide inhibits voltage-gated potassium channels mKv1.3/KCNA3 (IC50=1.70 µM), mKv1.1/KCNA1 (10 µM inhibits 40% of currents)
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and hKv1.2/KCNA2 (10 µM inhibits 42% of currents).
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Potassium channel toxin Meg-beta-KTx1

 Potassium channel toxin Meg-beta-KTx1 ELISA Kit
 Potassium channel toxin Meg-beta-KTx1 Recombinant
 Potassium channel toxin Meg-beta-KTx1 Antibody
Also known as Potassium channel toxin Meg-beta-KTx1 (MegbetaKTx1) (Beta potassium channel toxin 1).
Blocks voltage-gated potassium channels.
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Potassium channel toxin MeuTXK-beta-1

 Potassium channel toxin MeuTXK-beta-1 ELISA Kit
 Potassium channel toxin MeuTXK-beta-1 Recombinant
 Potassium channel toxin MeuTXK-beta-1 Antibody
Also known as Potassium channel toxin MeuTXK-beta-1 (MeuTXKbeta1).
Has a low affinity binding to potassium channels of rat brain synaptosomes. Displays weak antibacterial activity against Stenotrop
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homonas sp. Strongly inhibits the development of the Plasmodium berghei ookinetes. Displays slight hemolytic effect on mouse erythrocytes. Induces cytolysis on Xenopus oocytes at high concentrations. Is not toxic on mice and on the insect Tenebrio molitor.
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Potassium channel toxin MeuTXK-beta-2

 Potassium channel toxin MeuTXK-beta-2 ELISA Kit
 Potassium channel toxin MeuTXK-beta-2 Recombinant
 Potassium channel toxin MeuTXK-beta-2 Antibody
Also known as Potassium channel toxin MeuTXK-beta-2 (MeuTXKbeta2).
Has a low affinity binding to potassium channels of rat brain synaptosomes. Displays weak antibacterial activity against Stenotrop
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homonas sp. Strongly inhibits the development of the Plasmodium berghei ookinetes. Displays slight hemolytic effect on mouse erythrocytes. Induces cytolysis on Xenopus oocytes at high concentrations. Is not toxic on mice and on the insect Tenebrio molitor ().
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Potassium channel toxin MeuTXKbeta3

 Potassium channel toxin MeuTXKbeta3 ELISA Kit
 Potassium channel toxin MeuTXKbeta3 Recombinant
 Potassium channel toxin MeuTXKbeta3 Antibody
Also known as Potassium channel toxin MeuTXKbeta3 (BeL-5) (BeL-69).
MeuTXKbeta3 inhibits voltage-gated potassium channels.
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Potassium channel toxin TcoKIK

 Potassium channel toxin TcoKIK ELISA Kit
 Potassium channel toxin TcoKIK Recombinant
 Potassium channel toxin TcoKIK Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin Tdi-beta-KTx

 Potassium channel toxin Tdi-beta-KTx ELISA Kit
 Potassium channel toxin Tdi-beta-KTx Recombinant
 Potassium channel toxin Tdi-beta-KTx Antibody
Also known as Potassium channel toxin Tdi-beta-KTx (TdibetaKTx).
Blocks voltage-gated potassium channels.
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Potassium channel toxin TdiKIK

 Potassium channel toxin TdiKIK ELISA Kit
 Potassium channel toxin TdiKIK Recombinant
 Potassium channel toxin TdiKIK Antibody
Also known as Potassium channel toxin TdiKIK (TdKIK).
Blocks voltage-gated potassium channels.
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Potassium channel toxin Tst-beta-KTx

 Potassium channel toxin Tst-beta-KTx ELISA Kit
 Potassium channel toxin Tst-beta-KTx Recombinant
 Potassium channel toxin Tst-beta-KTx Antibody
Also known as Potassium channel toxin Tst-beta-KTx (TstbetaKTx).
Blocks potassium channels Kv1.1/KCNA1, Kv1.2/KCNA2, and Kv1.3/KCNA3.
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Potassium channel toxin TstKMK

 Potassium channel toxin TstKMK ELISA Kit
 Potassium channel toxin TstKMK Recombinant
 Potassium channel toxin TstKMK Antibody
Also known as Potassium channel toxin TstKMK (Toxin 5536) (beta-Ktx).
Blocks voltage-gated potassium channels (Kv).
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Potassium channel toxin TsTXK-beta

 Potassium channel toxin TsTXK-beta ELISA Kit
 Potassium channel toxin TsTXK-beta Recombinant
 Potassium channel toxin TsTXK-beta Antibody
Also known as Potassium channel toxin TsTXK-beta (Potassium channel toxin beta-KTx 1) (Tityustoxin K-beta) (TsTX K beta) (TsTX-K beta) (TsTXKbeta) (Ts8) (TsK2).
Specifically blocks voltage-gated po
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tassium channels Kv4.2/KCND2. When measured at the peak current, the blocking effect of this toxin is about 65% and shows an IC50=652 nM (PubMed:27346450). However, when measured at a later moment of the depolarising test pulse (500 ms), a 100% block of the current is observed with an IC50=313 nM (PubMed:27346450). This may indicate a preference ot the toxin for binding the inactivated state of the channel. The inhibition is completely reversible (PubMed:27346450). Using intraplantar injections on rat, this toxin induces overt nociception (licking and lifting behaviors) and decreases the mechanical nociceptive threshold (hyperalgesia). Furthermore, the hyperalgesia is prolonged when intrathecal injections are performed (PubMed:27346450).
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Potassium channel toxin Ttr-beta-KTx

 Potassium channel toxin Ttr-beta-KTx ELISA Kit
 Potassium channel toxin Ttr-beta-KTx Recombinant
 Potassium channel toxin Ttr-beta-KTx Antibody
Also known as Potassium channel toxin Ttr-beta-KTx (TtrbetaKTx).
Blocks voltage-gated potassium channels.
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Potassium channel toxin TtrKIK

 Potassium channel toxin TtrKIK ELISA Kit
 Potassium channel toxin TtrKIK Recombinant
 Potassium channel toxin TtrKIK Antibody
Blocks voltage-gated potassium channels.
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Potassium channel toxin-like Tx677

 Potassium channel toxin-like Tx677 ELISA Kit
 Potassium channel toxin-like Tx677 Recombinant
 Potassium channel toxin-like Tx677 Antibody
Inhibits voltage-gated potassium channels.
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Proteins Root Name Listing
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