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Presenilin

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Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptor. Required for S3 cleavage of Notch, which releases activated Notch protein from the cell membrane. Involved in the patterning of the optic lobes.

Below are the list of possible Presenilin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Presenilin homolog

 Presenilin homolog ELISA Kit
 Presenilin homolog Recombinant
 Presenilin homolog Antibody
Also known as Presenilin homolog (DmPS) (dPS).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptor. Required for S3 cleavage of Notch, which releases activated Notch protein from the cell membrane. Involved in the patterning of the optic lobes.
 Psn ELISA Kit
 Psn Recombinant
 Psn Antibody
 PS ELISA Kit
 PS Recombinant
 PS Antibody
 CG18803 ELISA Kit
 CG18803 Recombinant
 CG18803 Antibody
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Presenilin hop-1

 Presenilin hop-1 ELISA Kit
 Presenilin hop-1 Recombinant
 Presenilin hop-1 Antibody
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Probably works redundantly of lin-12, which provides more presenilin function.
 hop-1 ELISA Kit
 hop-1 Recombinant
 hop-1 Antibody
 C18E3.8 ELISA Kit
 C18E3.8 Recombinant
 C18E3.8 Antibody
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Presenilin sel-12

 Presenilin sel-12 ELISA Kit
 Presenilin sel-12 Recombinant
 Presenilin sel-12 Antibody
Also known as Presenilin sel-12 (Suppressor/enhancer of lin-12 protein 12).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Provides the major presenilin function compared to hop-1 and spe-4. Required cell-autonomously for correct neurite connecti
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vity of the AIY cholinergic interneurons and their correct functioning in thermotaxis. Required for mesodermal patterning of muscle function.
 sel-12 ELISA Kit
 sel-12 Recombinant
 sel-12 Antibody
 F35H12.3 ELISA Kit
 F35H12.3 Recombinant
 F35H12.3 Antibody
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Presenilin spe-4

 Presenilin spe-4 ELISA Kit
 Presenilin spe-4 Recombinant
 Presenilin spe-4 Antibody
Potential catalytic subunit of the gamma-secretase complex during spermatogenesis, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors (lin-12 or glp-1). Involved in spermatid formation during meiosis II. May be required for proper localization of macromolecules that are subject to asymmetric partitioning during spermatogenesis.
 spe-4 ELISA Kit
 spe-4 Recombinant
 spe-4 Antibody
 ZK524.1 ELISA Kit
 ZK524.1 Recombinant
 ZK524.1 Antibody
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Presenilin-1

 Presenilin-1 ELISA Kit
 Presenilin-1 Recombinant
 Presenilin-1 Antibody
Also known as Presenilin-1 (PS-1).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene ex
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pression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis ().
 PSEN1 ELISA Kit
 PSEN1 Recombinant
 PSEN1 Antibody
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Presenilin-2

 Presenilin-2 ELISA Kit
 Presenilin-2 Recombinant
 Presenilin-2 Antibody
Also known as Presenilin-2 (PS-2).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins ().
 PSEN2 ELISA Kit
 PSEN2 Recombinant
 PSEN2 Antibody
 PS2 ELISA Kit
 PS2 Recombinant
 PS2 Antibody
 PSNL2 ELISA Kit
 PSNL2 Recombinant
 PSNL2 Antibody
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Presenilin-A

 Presenilin-A ELISA Kit
 Presenilin-A Recombinant
 Presenilin-A Antibody
Also known as Presenilin-A (PS-A).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity ().
 psenA ELISA Kit
 psenA Recombinant
 psenA Antibody
 DDB_G0291352 ELISA Kit
 DDB_G0291352 Recombinant
 DDB_G0291352 Antibody
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Presenilin-B

 Presenilin-B ELISA Kit
 Presenilin-B Recombinant
 Presenilin-B Antibody
Also known as Presenilin-B (PS-B).
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Requires the other members of the gamma-secretase complex to have a protease activity ().
 psenB ELISA Kit
 psenB Recombinant
 psenB Antibody
 DDB_G0292310 ELISA Kit
 DDB_G0292310 Recombinant
 DDB_G0292310 Antibody
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