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Pro-neuregulin-4, membrane-bound isoform ELISA Kit Pro-neuregulin-4, membrane-bound isoform Recombinant Pro-neuregulin-4, membrane-bound isoform Antibody | Also known as Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4). NRG4: Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Belongs to the neuregulin family.
Protein type: Membrane >>> protein, integral
Chromosomal Location of Human Ortholog: 15q24.2
Cellular Component: extracellular region; extracellular space
Molecular Function: phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor binding
Biological Process: MAPKKK cascade; organ development; phosphoinositide-mediated signaling; regulation of phosphoinositide 3-kinase cascade |
NRG4 ELISA Kit NRG4 Recombinant NRG4 Antibody |
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