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Pro-vaccinia growth factor

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Vaccinia growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular-signal regulated kinases (ERK) are essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo.

Below are the list of possible Pro-vaccinia growth factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pro-vaccinia growth factor

 Pro-vaccinia growth factor ELISA Kit
 Pro-vaccinia growth factor Recombinant
 Pro-vaccinia growth factor Antibody
Also known as Pro-vaccinia growth factor (Pro-VGF).
Vaccinia growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular-signal regulated kinases (ERK) are
>>>
essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo.
 VGF-1 ELISA Kit
 VGF-1 Recombinant
 VGF-1 Antibody
 VACWR009 ELISA Kit
 VACWR009 Recombinant
 VACWR009 Antibody
 VGF-2 ELISA Kit
 VGF-2 Recombinant
 VGF-2 Antibody
 VACWR210 ELISA Kit
 VACWR210 Recombinant
 VACWR210 Antibody
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