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Pro-variola growth factor

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Variola growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular-signal regulated kinases (ERK) are essential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo (By similarity).

Below are the list of possible Pro-variola growth factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Pro-variola growth factor

 Pro-variola growth factor ELISA Kit
 Pro-variola growth factor Recombinant
 Pro-variola growth factor Antibody
Also known as Pro-variola growth factor (Pro-VGF).
Variola growth factor stimulates cellular proliferation (hyperplasia) around infected cells. This effect is beneficial for virus replication in vivo, because poxviruses replicate possibly better in proliferating cells than in quiescent cells. Acts by binding host EGFR, inducing its dimerization, autophosphorylation and leading to activation of several cellular pathways regulating cell proliferation or cell survival. The activation by host EFGR of mitogen activated protein kinases (MAPK) and extracellular-signal regulated kinases (ERK) are e
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ssential for the positive effect of vaccinia growth factor on poxvirus virulence in vivo ().
 B3R ELISA Kit
 B3R Recombinant
 B3R Antibody
 B4R ELISA Kit
 B4R Recombinant
 B4R Antibody
 C11R ELISA Kit
 C11R Recombinant
 C11R Antibody
 D2L ELISA Kit
 D2L Recombinant
 D2L Antibody
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