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Prospero homeobox protein

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Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.

Below are the list of possible Prospero homeobox protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Prospero homeobox protein 1

 Prospero homeobox protein 1 ELISA Kit
 Prospero homeobox protein 1 Recombinant
 Prospero homeobox protein 1 Antibody
Also known as Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1).
PROX1: May play a fundamental role in early development of CNS. May regulate gene expression and development of postmitotic undifferentiated young neurons. Belongs to the Prospero homeobox family.

Protein type: DNA-binding; Nuclear receptor co-regulator; Transcription factor

Cellular Compone
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nt: cytoplasm; nucleus

Molecular Function: DBD domain binding; DNA binding; LBD domain binding; ligand-dependent nuclear receptor binding; protein binding; RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription corepressor activity

Biological Process: atrial cardiac muscle morphogenesis; cell fate determination; cerebellar granule cell differentiation; circadian rhythm; dentate gyrus development; embryonic retina morphogenesis in camera-type eye; endothelial cell differentiation; inner ear development; lens morphogenesis in camera-type eye; lymph vessel development; lymphangiogenesis; muscle thin filament assembly; negative regulation of cell proliferation; negative regulation of transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of viral genome replication; optic placode formation involved in camera-type eye; positive regulation of cell cycle; positive regulation of cell proliferation; positive regulation of cyclin-dependent protein kinase activity; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of circadian rhythm; regulation of gene expression; venous blood vessel morphogenesis; ventricular cardiac muscle morphogenesis; ventricular cardiac myofibril development
 Prox1 ELISA Kit
 Prox1 Recombinant
 Prox1 Antibody
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Prospero homeobox protein 2

 Prospero homeobox protein 2 ELISA Kit
 Prospero homeobox protein 2 Recombinant
 Prospero homeobox protein 2 Antibody
Also known as Prospero homeobox protein 2 (Homeobox prospero-like protein PROX2) (PROX-2).
PROX2: Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival. Belongs to the Prospero homeobox family. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: nucleus

Biological Process: cardiac muscle cell d
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ifferentiation; negative regulation of transcription from RNA polymerase II promoter; neuron differentiation; positive regulation of transcription from RNA polymerase II promoter
 Prox2 ELISA Kit
 Prox2 Recombinant
 Prox2 Antibody
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