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Prostaglandin D2 receptor

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Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).

Below are the list of possible Prostaglandin D2 receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Prostaglandin D2 receptor

 Prostaglandin D2 receptor ELISA Kit
 Prostaglandin D2 receptor Recombinant
 Prostaglandin D2 receptor Antibody
Also known as Prostaglandin D2 receptor (PGD receptor) (PGD2 receptor) (Prostanoid DP receptor).
PTGDR: Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate. Genetic
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variations in PTGDR are associated with susceptibility to asthma-related traits type 1 (ASRT1). Asthma-related traits include clinical symptoms of asthma, such as coughing, wheezing and dyspnea. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 14q22.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: prostacyclin receptor activity; prostaglandin D receptor activity; protein binding

Biological Process: elevation of cytosolic calcium ion concentration; G-protein signaling, adenylate cyclase activating pathway; inflammatory response; positive regulation of vasodilation

Disease: Asthma-related Traits, Susceptibility To, 1
 PTGDR ELISA Kit
 PTGDR Recombinant
 PTGDR Antibody
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Prostaglandin D2 receptor 2

 Prostaglandin D2 receptor 2 ELISA Kit
 Prostaglandin D2 receptor 2 Recombinant
 Prostaglandin D2 receptor 2 Antibody
Also known as Prostaglandin D2 receptor 2 (Chemoattractant receptor-homologous molecule expressed on Th2 cells) (G-protein coupled receptor 44) (CD antigen CD294).
GPR44: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin- sensitive decreases in cAMP levels and Ca(2+) mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, ADRBK1/GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible,
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at least in part, in immune regulation and allergic/inflammation responses. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 11q12-q13.3

Cellular Component: integral to plasma membrane; neuron projection; plasma membrane

Molecular Function: G-protein coupled receptor activity; neuropeptide binding; prostaglandin D receptor activity

Biological Process: calcium-mediated signaling; chemotaxis; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; immune response; neuropeptide signaling pathway; synaptic transmission
 PTGDR2 ELISA Kit
 PTGDR2 Recombinant
 PTGDR2 Antibody
 CRTH2 ELISA Kit
 CRTH2 Recombinant
 CRTH2 Antibody
 DL1R ELISA Kit
 DL1R Recombinant
 DL1R Antibody
 GPR44 ELISA Kit
 GPR44 Recombinant
 GPR44 Antibody
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Prostaglandin D2 receptor-like

 Prostaglandin D2 receptor-like ELISA Kit
 Prostaglandin D2 receptor-like Recombinant
 Prostaglandin D2 receptor-like Antibody
Also known as Prostaglandin D2 receptor-like (PGD receptor-like) (PGD2 receptor-like) (Prostanoid DP receptor-like).
receptor for prostaglandin D2, may play a role in vision, regulation of intraocular pressure, and sleep induction [RGD, Feb 2006]
 Ptgdrl ELISA Kit
 Ptgdrl Recombinant
 Ptgdrl Antibody
 Ptgdr2 ELISA Kit
 Ptgdr2 Recombinant
 Ptgdr2 Antibody
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Proteins Root Name Listing
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