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Prostaglandin G/H synthase

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Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells (By similarity).

Below are the list of possible Prostaglandin G/H synthase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Prostaglandin G/H synthase 1

 Prostaglandin G/H synthase 1 ELISA Kit
 Prostaglandin G/H synthase 1 Recombinant
 Prostaglandin G/H synthase 1 Antibody
Also known as Prostaglandin G/H synthase 1 (Cyclooxygenase-1) (COX-1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1) (Prostaglandin-endoperoxide synthase 1).
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it
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is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells ().
 PTGS1 ELISA Kit
 PTGS1 Recombinant
 PTGS1 Antibody
 COX1 ELISA Kit
 COX1 Recombinant
 COX1 Antibody
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Prostaglandin G/H synthase 2

 Prostaglandin G/H synthase 2 ELISA Kit
 Prostaglandin G/H synthase 2 Recombinant
 Prostaglandin G/H synthase 2 Antibody
Also known as Prostaglandin G/H synthase 2 (Cyclooxygenase-2) (COX-2) (Glucocorticoid-regulated inflammatory cyclooxygenase) (Gripghs) (Macrophage activation-associated marker protein P71/73) (PES-2) (PHS II) (Prostaglandin H2 synthase 2) (PGH synthase 2.
COX-2: Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity. Homodimer. Belongs to the prostaglandin G/H synthase family.

Protein type: EC 1.14.99.1; Lipid Metabolism - arachidonic acid; Oxidoreductase >>>
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Cellular Component: caveola; cytoplasm; endoplasmic reticulum; neuron projection; nucleus; protein complex

Molecular Function: enzyme binding; heme binding; lipid binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; prostaglandin-endoperoxide synthase activity; protein homodimerization activity

Biological Process: anagen; angiogenesis; bone mineralization; brown fat cell differentiation; cyclooxygenase pathway; decidualization; embryo implantation; inflammatory response; learning; memory; negative regulation of calcium ion transport; negative regulation of cell cycle; negative regulation of cell proliferation; negative regulation of smooth muscle contraction; negative regulation of synaptic transmission, dopaminergic; ovulation; positive regulation of apoptosis; positive regulation of cell proliferation; positive regulation of fever; positive regulation of NF-kappaB import into nucleus; positive regulation of nitric oxide biosynthetic process; positive regulation of smooth muscle cell proliferation; positive regulation of smooth muscle contraction; positive regulation of synaptic plasticity; positive regulation of synaptic transmission, glutamatergic; positive regulation of vasoconstriction; prostaglandin biosynthetic process; regulation of blood pressure; regulation of cell proliferation; response to cytokine stimulus; response to lipopolysaccharide; sensory perception of pain
 Ptgs2 ELISA Kit
 Ptgs2 Recombinant
 Ptgs2 Antibody
 Cox-2 ELISA Kit
 Cox-2 Recombinant
 Cox-2 Antibody
 Cox2 ELISA Kit
 Cox2 Recombinant
 Cox2 Antibody
 Pghs-b ELISA Kit
 Pghs-b Recombinant
 Pghs-b Antibody
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