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Proteasomal ATPase-associated factor

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Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency. Protects SUPT6H from proteasomal degradation.

Below are the list of possible Proteasomal ATPase-associated factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Proteasomal ATPase-associated factor 1

 Proteasomal ATPase-associated factor 1 ELISA Kit
 Proteasomal ATPase-associated factor 1 Recombinant
 Proteasomal ATPase-associated factor 1 Antibody
Also known as Proteasomal ATPase-associated factor 1 (Protein G-16) (WD repeat-containing protein 71).
PAAF1: Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociat
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ion of the proteasome 26S. This presumably promotes provirus transcription efficiency. Belongs to the WD repeat PAAF1/RPN14 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 11q13.4

Cellular Component: proteasome complex

Molecular Function: protein binding
 PAAF1 ELISA Kit
 PAAF1 Recombinant
 PAAF1 Antibody
 WDR71 ELISA Kit
 WDR71 Recombinant
 WDR71 Antibody
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