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Proteasome activator complex

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Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Below are the list of possible Proteasome activator complex products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Proteasome activator complex subunit 1

 Proteasome activator complex subunit 1 ELISA Kit
 Proteasome activator complex subunit 1 Recombinant
 Proteasome activator complex subunit 1 Antibody
Also known as Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha).
PSME1: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex en
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hances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. Heterodimer of PSME1 and PSME2, which forms a hexadimeric ring. PSME1 can form homoheptamers. By IFNG/IFN-gamma. Belongs to the PA28 family.

Protein type: Proteasome complex

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: cytoplasm; cytosol; nucleoplasm; proteasome complex

Molecular Function: protein binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; MAPKKK cascade; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway
 PSME1 ELISA Kit
 PSME1 Recombinant
 PSME1 Antibody
 IFI5111 ELISA Kit
 IFI5111 Recombinant
 IFI5111 Antibody
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Proteasome activator complex subunit 2

 Proteasome activator complex subunit 2 ELISA Kit
 Proteasome activator complex subunit 2 Recombinant
 Proteasome activator complex subunit 2 Antibody
Also known as Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta).
PSME2: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the
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cleavage pattern of the proteasome. Heterodimer of PSME1 and PSME2, which forms a hexadimeric ring. By IFNG/IFN-gamma. Belongs to the PA28 family.

Protein type: Protease; Proteasome complex

Cellular Component: cytoplasm; membrane; proteasome complex

Molecular Function: protein binding

Biological Process: antigen processing and presentation of exogenous antigen
 Psme2 ELISA Kit
 Psme2 Recombinant
 Psme2 Antibody
 Pa28b1 ELISA Kit
 Pa28b1 Recombinant
 Pa28b1 Antibody
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Proteasome activator complex subunit 3

 Proteasome activator complex subunit 3 ELISA Kit
 Proteasome activator complex subunit 3 Recombinant
 Proteasome activator complex subunit 3 Antibody
Also known as Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma).
PSME3: a protein implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of c
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lass I binding peptides by altering the cleavage pattern of the proteasome. Homohexamer. Significantly elevated in colorectal cancer patients compared with healthy donors and patients with benign bowel disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Protease; Proteasome complex

Cellular Component: cytoplasm; membrane; nucleoplasm; nucleus; proteasome complex

Molecular Function: identical protein binding; p53 binding
 Psme3 ELISA Kit
 Psme3 Recombinant
 Psme3 Antibody
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Proteasome activator complex subunit 4

 Proteasome activator complex subunit 4 ELISA Kit
 Proteasome activator complex subunit 4 Recombinant
 Proteasome activator complex subunit 4 Antibody
Also known as Proteasome activator complex subunit 4 (Proteasome activator PA200).
PSME4: Activates proteasomal cleavage of peptides in an energy- independent manner. May be involved in spermatogenesis. May be involved in DNA repair. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2p16.2

Cellular Component: cytosol; nuc
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leus; proteasome core complex

Molecular Function: protease activator activity; protein binding

Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; DNA repair; MAPKKK cascade; positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-independent protein catabolic process; protein polyubiquitination; regulation of amino acid metabolic process; regulation of mRNA stability; response to DNA damage stimulus; spermatogenesis, exchange of chromosomal proteins; stimulatory C-type lectin receptor signaling pathway; T cell receptor signaling pathway; tumor necrosis factor-mediated signaling pathway; Wnt receptor signaling pathway, planar cell polarity pathway
 PSME4 ELISA Kit
 PSME4 Recombinant
 PSME4 Antibody
 KIAA0077 ELISA Kit
 KIAA0077 Recombinant
 KIAA0077 Antibody
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Proteasome activator complex subunit 4A

 Proteasome activator complex subunit 4A ELISA Kit
 Proteasome activator complex subunit 4A Recombinant
 Proteasome activator complex subunit 4A Antibody
Also known as Proteasome activator complex subunit 4A (Proteasome activator PA200-A).
Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening th
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e gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones ().
 psme4a ELISA Kit
 psme4a Recombinant
 psme4a Antibody
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Proteasome activator complex subunit 4B

 Proteasome activator complex subunit 4B ELISA Kit
 Proteasome activator complex subunit 4B Recombinant
 Proteasome activator complex subunit 4B Antibody
Also known as Proteasome activator complex subunit 4B (Proteasome activator PA200-B).
Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening th
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e gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones ().
 psme4b ELISA Kit
 psme4b Recombinant
 psme4b Antibody
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Proteins Root Name Listing
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