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Protein LYRIC

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Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Below are the list of possible Protein LYRIC products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Protein LYRIC

 Protein LYRIC ELISA Kit
 Protein LYRIC Recombinant
 Protein LYRIC Antibody
Also known as Protein LYRIC (3D3/LYRIC) (Astrocyte elevated gene-1 protein) (AEG-1) (Lysine-rich CEACAM1 co-isolated protein) (Metadherin) (Metastasis adhesion protein).
Lyric: a protein of unknown function.

Protein type: Cell adhesion; Membrane protein, integral; Nucleolus

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: apical plasma membrane; cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; intercellular canaliculus; nuclear body; nucleolus; nucleus; perinuclear region of cytoplasm; tight junction

Molecular Function: double-
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stranded RNA binding; NF-kappaB binding; protein binding; transcription coactivator activity

Biological Process: activation of NF-kappaB transcription factor; lipopolysaccharide-mediated signaling pathway; negative regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; positive regulation of angiogenesis; positive regulation of autophagy; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein kinase B signaling cascade
 MTDH ELISA Kit
 MTDH Recombinant
 MTDH Antibody
 AEG1 ELISA Kit
 AEG1 Recombinant
 AEG1 Antibody
 LYRIC ELISA Kit
 LYRIC Recombinant
 LYRIC Antibody
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