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Protein numb

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Required in determination of cell fate during sensory organ formation in embryos. Functions in nuclei and seems to interact with nucleic acids.

Below are the list of possible Protein numb products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Protein numb

 Protein numb ELISA Kit
 Protein numb Recombinant
 Protein numb Antibody
Required in determination of cell fate during sensory organ formation in embryos. Functions in nuclei and seems to interact with nucleic acids.
 numb ELISA Kit
 numb Recombinant
 numb Antibody
 CG3779 ELISA Kit
 CG3779 Recombinant
 CG3779 Antibody
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Protein numb homolog

 Protein numb homolog ELISA Kit
 Protein numb homolog Recombinant
 Protein numb homolog Antibody
NUMB: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (S
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VZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. Interacts with CDH1 and TFAP2B. Interacts with EPS15, LNX and NOTCH1. May interact with DUOXA1. Interacts with RALBP1 in a complex also containing EPN1 and TFAP2A during interphase and mitosis. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell development/differentiation

Cellular Component: apical part of cell; apical plasma membrane; basolateral plasma membrane; clathrin-coated vesicle; cytoplasm; cytoplasmic vesicle; early endosome; extrinsic to plasma membrane; focal adhesion; nucleus

Molecular Function: alpha-catenin binding; beta-catenin binding; cadherin binding; protein binding

Biological Process: axonogenesis; forebrain development; lateral ventricle development; negative regulation of Notch signaling pathway; nervous system development; neuroblast division in the subventricular zone; neuroblast proliferation; positive regulation of cell migration; positive regulation of dendrite morphogenesis; positive regulation of neurogenesis; positive regulation of polarized epithelial cell differentiation; regulation of neuron differentiation
 Numb ELISA Kit
 Numb Recombinant
 Numb Antibody
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