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Protein phosphatase 1 regulatory inhibitor

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Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Below are the list of possible Protein phosphatase 1 regulatory inhibitor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Protein phosphatase 1 regulatory inhibitor subunit 16B

 Protein phosphatase 1 regulatory inhibitor subunit 16B ELISA Kit
 Protein phosphatase 1 regulatory inhibitor subunit 16B Recombinant
 Protein phosphatase 1 regulatory inhibitor subunit 16B Antibody
Also known as Protein phosphatase 1 regulatory inhibitor subunit 16B (Ankyrin repeat domain-containing protein 4) (CAAX box protein TIMAP) (TGF-beta-inhibited membrane-associated protein) (hTIMAP).
PPP1R16B: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulatio
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n of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Protein type: Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 20q11.23

Cellular Component: cell projection; nucleus; perinuclear region of cytoplasm; plasma membrane

Molecular Function: protein binding; protein phosphatase regulator activity

Biological Process: negative regulation of protein amino acid dephosphorylation; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid dephosphorylation; regulation of filopodium formation; regulation of phosphoinositide 3-kinase cascade
 PPP1R16B ELISA Kit
 PPP1R16B Recombinant
 PPP1R16B Antibody
 ANKRD4 ELISA Kit
 ANKRD4 Recombinant
 ANKRD4 Antibody
 KIAA0823 ELISA Kit
 KIAA0823 Recombinant
 KIAA0823 Antibody
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