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Protein phosphatase inhibitor

Inhibitor of protein-phosphatase 1.

Below are the list of possible Protein phosphatase inhibitor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Protein phosphatase inhibitor 2

 Protein phosphatase inhibitor 2 ELISA Kit
 Protein phosphatase inhibitor 2 Recombinant
 Protein phosphatase inhibitor 2 Antibody
Also known as Protein phosphatase inhibitor 2 (IPP-2).
PPP1R2: a member of the protein phosphatase inhibitor 1 family. A dopamine- and cyclic AMP-regulated neuronal phosphoprotein. Both dopaminergic and glutamatergic (NMDA) receptor stimulation regulate the extent of DARPP32 phosphorylation, but in opposite directions. Dopamine D1 receptor stimulation enhances cAMP formation, resulting in the
phosphorylation of DARPP32; phosphorylated DARPP32 is a potent protein phosphatase-1 inhibitor. NMDA receptor stimulation elevates intracellular calcium, which leads to activation of calcineurin and dephosphorylation of phospho-DARPP32, thereby reducing the phosphatase-1 inhibitory activity of DARPP32. Two alternatively-spliced isoforms have been described.

Protein type: Inhibitor; Motility/polarity/chemotaxis; Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: protein phosphatase type 1 complex

Molecular Function: protein binding; type 1 serine/threonine specific protein phosphatase inhibitor activity

Biological Process: generation of precursor metabolites and energy; regulation of phosphoprotein phosphatase activity
 PPP1R2 Recombinant
 PPP1R2 Antibody
 IPP2 Recombinant
 IPP2 Antibody
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