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Protein timeless

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Required for the production of circadian rhythms. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition (By similarity).

Below are the list of possible Protein timeless products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Protein timeless

 Protein timeless ELISA Kit
 Protein timeless Recombinant
 Protein timeless Antibody
Required for the production of circadian rhythms. The biological cycle depends on the rhythmic formation and nuclear localization of the TIM-PER complex. Light induces the degradation of TIM, which promotes elimination of PER. Nuclear activity of the heterodimer coordinatively regulates PER and TIM transcription through a negative feedback loop. Behaves as a negative element in circadian transcrip
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tional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition ().
 tim ELISA Kit
 tim Recombinant
 tim Antibody
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Protein timeless homolog

 Protein timeless homolog ELISA Kit
 Protein timeless homolog Recombinant
 Protein timeless homolog Antibody
Plays an important role in chromosome cohesion during both mitosis and meiosis (PubMed:12827206). In prophase of meiosis, it is involved in the formation of the synaptonemal complex (SC) and specifically, in the diplotene and diakinesis phases of prophase, it stabilizes the association of homologous chromosomes during synapsis and sister chromatid cohesion (PubMed:12827206). It regulates cohesin s
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ubunits to promote meiotic chromosome cohesion and localizes non-SMC (structural maintenance of chromosome) cohesin subunits to chromatin prior to or during pre-meiotic S phase (PubMed:12827206). Implicated in influencing either the stability or loading of meiotic-specific cohesin subunit, rec8 (PubMed:12827206). Controls cell cycle exit and cell fusion to prevent the premature differentiation into adult cells (PubMed:15691769). Specifically, regulates hypodermal seam cell identity (PubMed:15691769).
 tim-1 ELISA Kit
 tim-1 Recombinant
 tim-1 Antibody
 Y75B8A.22 ELISA Kit
 Y75B8A.22 Recombinant
 Y75B8A.22 Antibody
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