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Protein wntless

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A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserved protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip (By similarity).

Below are the list of possible Protein wntless products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Protein wntless

 Protein wntless ELISA Kit
 Protein wntless Recombinant
 Protein wntless Antibody
A segment polarity gene required for wingless (wg)-dependent patterning processes, acting in both wg-sending cells and wg-target cells. In non-neuronal cells wls directs wg secretion. The wls traffic loop encompasses the Golgi, the cell surface, an endocytic compartment and a retrograde route leading back to the Golgi, and involves clathrin-mediated endocytosis and the retromer complex (a conserve
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d protein complex consisting of Vps35 and Vps26). In neuronal cells (the larval motorneuron NMJ), the wg signal moves across the synapse via the release of wls-containing exosome-like vesicles. Postsynaptic wls is required for the trafficking of fz2 through the fz2-interacting protein Grip ().
 wls ELISA Kit
 wls Recombinant
 wls Antibody
 GF24563 ELISA Kit
 GF24563 Recombinant
 GF24563 Antibody
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Protein wntless homolog

 Protein wntless homolog ELISA Kit
 Protein wntless homolog Recombinant
 Protein wntless homolog Antibody
Also known as Protein wntless homolog (Abnormal cell migration protein 14).
Probable sorting receptor which regulates endocytosis and secretion of the wnt ligand egl-20 (PubMed:18160346, PubMed:18160347, PubMed:21076391). Recycling of mig-14 from the plasma membrane to the Golgi apparatus by the retromer complex is essential for its function (PubMed:18160346, PubMed:18160347, PubMed:21076391). Its endosomal trafficking is regulated by its association with sorting nexin snx-3 on early endosomes and the mtm-6/mtm-9 myotubularin complex (PubMed:21076391). Required in embryonic development for
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endoderm specification and the correct positioning and orientation of the mitotic spindles and division planes in blastomere cells (PubMed:9288749, PubMed:16678095). Functions during vulval development, playing a role in vulval precursor cell fate specification (PubMed:11063687, PubMed:18077322). During development, specifically regulates the migration of HSN neurons, the left Q neuroblast (QL) and its descendants and the distal tip cells of the gonads (PubMed:8898225, PubMed:10388818, PubMed:11063687, PubMed:18160346, PubMed:18160347). Positioning of Q neuroblasts may be both dependent and independent of hox gene mab-5 (PubMed:8898225). Involved in establishing ALM and PLM neuronal cell polarity (PubMed:18160346).
 mig-14 ELISA Kit
 mig-14 Recombinant
 mig-14 Antibody
 mom-3 ELISA Kit
 mom-3 Recombinant
 mom-3 Antibody
 R06B9.6 ELISA Kit
 R06B9.6 Recombinant
 R06B9.6 Antibody
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Protein wntless homolog A

 Protein wntless homolog A ELISA Kit
 Protein wntless homolog A Recombinant
 Protein wntless homolog A Antibody
Also known as Protein wntless homolog A (Integral membrane protein GPR177-A).
Required for a subset of Wnt-dependent developmental processes, in particular, eye and pronephros development. Regulates the secretion of wnt4, which is required for eye development ().
 wls-a ELISA Kit
 wls-a Recombinant
 wls-a Antibody
 gpr177-a ELISA Kit
 gpr177-a Recombinant
 gpr177-a Antibody
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Protein wntless homolog B

 Protein wntless homolog B ELISA Kit
 Protein wntless homolog B Recombinant
 Protein wntless homolog B Antibody
Also known as Protein wntless homolog B (XWntless) (Integral membrane protein GPR177-B).
Required for a subset of Wnt-dependent developmental processes, in particular, eye and pronephros development. Regulates the secretion of wnt4, which is required for eye development.
 wls-b ELISA Kit
 wls-b Recombinant
 wls-b Antibody
 gpr177-b ELISA Kit
 gpr177-b Recombinant
 gpr177-b Antibody
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Proteins Root Name Listing
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