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Rab-3A-interacting protein

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Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).

Below are the list of possible Rab-3A-interacting protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Rab-3A-interacting protein

 Rab-3A-interacting protein ELISA Kit
 Rab-3A-interacting protein Recombinant
 Rab-3A-interacting protein Antibody
Also known as Rab-3A-interacting protein (Rab3A-interacting protein) (Rabin-3) (SSX2-interacting protein).
RAB3IP: Guanine nucleotide exchange factor for RAB8A. Mediates the release of GDP from RAB8A but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PR
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KCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. Belongs to the SEC2 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: GEFs; GEFs, Rab

Cellular Component: cytoplasm; cytosol; Golgi apparatus; nucleus; perinuclear region of cytoplasm

Molecular Function: GTPase binding; Rab guanyl-nucleotide exchange factor activity

Biological Process: negative regulation of filopodium formation; protein targeting to membrane
 Rab3ip ELISA Kit
 Rab3ip Recombinant
 Rab3ip Antibody
 Rabin8 ELISA Kit
 Rabin8 Recombinant
 Rabin8 Antibody
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